Calmodulin-2

BE0008705ProteinHumansCALM2

Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding (PubMed:16760425, PubMed:26969752, PubMed:27165696). It is acted on by 10 drugs in DrugBank.

Gene name
CALM2
UniProtKB entry
P0DP24Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton, spindle
Residues / weight
149 residues · 16,837 Da
Also known as
CAM2 · CAMB

Resolves to

Protein
UniProtP0DP24UniProt nameCALM2_HUMAN
Gene
HGNCHGNC:1445NCBI Gene808GeneCardsCALM2
Pharmacology
KEGGhsa:808
Structure
PDB3O77PDB3O78PDB5COC
Drugs

What you can answer from here — as of September 03, 2024

10DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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44+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calmodulin-2, how selective are they, and which programs against it are still in active trials?

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