Macrophage mannose receptor 1

BE0009334ProteinHumansMRC1

Mediates the endocytosis of glycoproteins by macrophages. It is acted on by 5 drugs in DrugBank.

Gene name
MRC1
UniProtKB entry
P22897Swiss-Prot
Cellular location
Endosome membrane
Residues / weight
1,456 residues · 166,010 Da
Also known as
C-type lectin domain family 13 member D · C-type lectin domain family 13 member D-like · CLEC13D · CLEC13DL · hMR

Resolves to

Protein
UniProtP22897UniProt nameMRC1_HUMAN
Gene
HGNCHGNC:7228NCBI Gene4360GeneCardsMRC1
Pharmacology
KEGGhsa:4360
Structure
PDB1EGGPDB1EGIPDB5XTS
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Macrophage mannose receptor 1, how selective are they, and which programs against it are still in active trials?

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