Mannose
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Mannose
- DrugBank Accession Number
- DB12907
- Background
Mannose is under investigation for the basic science of IUGR and Pregnancy.
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 180.1559
Monoisotopic: 180.063388116 - Chemical Formula
- C6H12O6
- Synonyms
- D-mannose
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity.
- Kingdom
- Organic compounds
- Super Class
- Organic oxygen compounds
- Class
- Organooxygen compounds
- Sub Class
- Carbohydrates and carbohydrate conjugates
- Direct Parent
- Hexoses
- Alternative Parents
- Medium-chain aldehydes / Beta-hydroxy aldehydes / Alpha-hydroxyaldehydes / Secondary alcohols / Polyols / Primary alcohols / Organic oxides / Hydrocarbon derivatives
- Substituents
- Alcohol / Aldehyde / Aliphatic acyclic compound / Alpha-hydroxyaldehyde / Beta-hydroxy aldehyde / Carbonyl group / Hexose monosaccharide / Hydrocarbon derivative / Medium-chain aldehyde / Organic oxide
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- D-mannose, aldehydo-mannose (CHEBI:37675)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- PHA4727WTP
- CAS number
- 3458-28-4
- InChI Key
- GZCGUPFRVQAUEE-KVTDHHQDSA-N
- InChI
- InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4-,5-,6-/m1/s1
- IUPAC Name
- (2S,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal
- SMILES
- [H][C@@](O)(CO)[C@@]([H])(O)[C@]([H])(O)[C@]([H])(O)C=O
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0062473
- PubChem Compound
- 161658
- PubChem Substance
- 347829059
- ChemSpider
- 141983
- 6633
- ChEBI
- 37675
- ZINC
- ZINC000002556396
- PDBe Ligand
- DNO
- Wikipedia
- Mannose
- PDB Entries
- 2wku / 2wl5 / 3bdk / 7z6t / 8wbv
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Recruiting Basic Science Health 1 somestatus stop reason just information to hide Not Available Terminated Basic Science IUGR / Pregnancy 1 somestatus stop reason just information to hide 4 Terminated Treatment Urinary Tract Infection 1 somestatus stop reason just information to hide 2, 3 Terminated Prevention Urinary Tract Infection 1 somestatus stop reason just information to hide 1 Withdrawn Treatment Cancer / Fever / Hematologic Disease and Disorders / Neutropenia 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 261.0 mg/mL ALOGPS logP -2.4 ALOGPS logP -3.6 Chemaxon logS 0.16 ALOGPS pKa (Strongest Acidic) 12.26 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 5 Chemaxon Polar Surface Area 118.22 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 37.35 m3·mol-1 Chemaxon Polarizability 16.24 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 141.8518761 predictedDarkChem Lite v0.1.0 [M-H]- 139.6551761 predictedDarkChem Lite v0.1.0 [M-H]- 141.3379761 predictedDarkChem Lite v0.1.0 [M-H]- 136.24312 predictedDeepCCS 1.0 (2019) [M+H]+ 145.2427761 predictedDarkChem Lite v0.1.0 [M+H]+ 142.8902761 predictedDarkChem Lite v0.1.0 [M+H]+ 142.5863761 predictedDarkChem Lite v0.1.0 [M+H]+ 138.63869 predictedDeepCCS 1.0 (2019) [M+Na]+ 141.0624761 predictedDarkChem Lite v0.1.0 [M+Na]+ 139.1495761 predictedDarkChem Lite v0.1.0 [M+Na]+ 141.4952761 predictedDarkChem Lite v0.1.0 [M+Na]+ 145.1082 predictedDeepCCS 1.0 (2019)
Drug created at October 21, 2016 01:10 / Updated at May 04, 2023 00:49