Dual specificity mitogen-activated protein kinase kinase 6

BE0009461ProteinHumansMAP2K6

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. It is acted on by 1 drug in DrugBank.

Gene name
MAP2K6
UniProtKB entry
P52564Swiss-Prot
Cellular location
Nucleus
Residues / weight
334 residues · 37,492 Da
Also known as
2.7.12.2 · MAP kinase kinase 6 · MAPK/ERK kinase 6 · MAPKK 6 · MEK 6

Resolves to

Protein
UniProtP52564UniProt nameMP2K6_HUMAN
Gene
HGNCHGNC:6846NCBI Gene5608GeneCardsMAP2K6
Pharmacology
IUPHAR/GtoPdb2067KEGGhsa:5608
Structure
PDB2Y8OPDB3ENMPDB3FME
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
12GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
31+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Dual specificity mitogen-activated protein kinase kinase 6, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In