5-hydroxytryptamine receptor 3B

BE0009583ProteinHumansHTR3B

Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. It is acted on by 7 drugs in DrugBank.

Gene name
HTR3B
UniProtKB entry
O95264Swiss-Prot
Cellular location
Postsynaptic cell membrane
Residues / weight
441 residues · 50,291 Da
Also known as
5-HT3-B · 5-HT3B · Serotonin receptor 3B

Resolves to

Protein
UniProtO95264UniProt name5HT3B_HUMAN
Gene
HGNCHGNC:5298NCBI Gene9177GeneCardsHTR3B
Pharmacology
IUPHAR/GtoPdb374KEGGhsa:9177
Drugs

What you can answer from here — as of August 08, 2024

7DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 5-hydroxytryptamine receptor 3B, how selective are they, and which programs against it are still in active trials?

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