Sulfotransferase 1C4

BE0009765ProteinHumansSULT1C4

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic compounds. It is acted on by 3 drugs in DrugBank.

Gene name
SULT1C4
UniProtKB entry
O75897Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
302 residues · 35,520 Da
Also known as
2.8.2.1 · ST1C4 · Sulfotransferase 1C2 · SULT1C#2 · SULT1C2

Resolves to

Protein
UniProtO75897UniProt nameST1C4_HUMAN
Gene
HGNCHGNC:11457NCBI Gene27233GeneCardsSULT1C4
Pharmacology
KEGGhsa:27233
Structure
PDB2AD1PDB2GWH
Drugs

What you can answer from here — as of September 25, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sulfotransferase 1C4, how selective are they, and which programs against it are still in active trials?

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