1,3-beta-glucan synthase component GSC2

BE0010066ProteinBaker's yeastGSC2

Alternate catalytic subunit of the 1,3-beta-glucan synthase (GS) complex. It is acted on by 6 drugs in DrugBank.

Gene name
GSC2
UniProtKB entry
P40989Swiss-Prot
Cellular location
Membrane
Residues / weight
1,895 residues · 216,988 Da
Also known as
1,3-beta-D-glucan-UDP glucosyltransferase · 2.4.1.34 · FK506 sensitivity protein 2 · FKS2 · GLS2

Resolves to

Protein
UniProtP40989UniProt nameFKS2_YEAST
Gene
NCBI Gene852920
Pharmacology
KEGGsce:YGR032W
Drugs

What you can answer from here — as of June 03, 2021

6DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 1,3-beta-glucan synthase component GSC2, how selective are they, and which programs against it are still in active trials?

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