Proto-oncogene Mas

BE0012496ProteinHumansMAS1

G protein-coupled receptor that plays key roles in the renin-angiotensin system (RAS) specifically in the protective, counter-regulatory arm of the RAS (PubMed:25967876). It is acted on by 4 drugs in DrugBank.

Gene name
MAS1
UniProtKB entry
P04201Swiss-Prot
Cellular location
Cell membrane
Residues / weight
325 residues · 37,465 Da
Also known as
MAS

Resolves to

Protein
UniProtP04201UniProt nameMAS_HUMAN
Gene
HGNCHGNC:6899NCBI Gene4142GeneCardsMAS1
Pharmacology
IUPHAR/GtoPdb150KEGGhsa:4142
Structure
PDB9JLCPDB9X3YPDB9X3Z
Drugs

What you can answer from here — as of September 03, 2024

4DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proto-oncogene Mas, and which indications are they being tested in?

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