20-Hydroxyecdysone

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DB16935InvestigationalSmall molecule

20-Hydroxyecdysone: Overview.

Mechanism: Pharmacologically active on Proto-oncogene Mas
Curator reviewed
Formula / weight: C₂₇H₄₄O₇ · 480.642 g/mol (avg)
Also known as: 20-hydroxy-.alpha.-ecdysone · Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2.beta.,3.beta.,5.beta.,22r)- · Commisterone · Crustecdyson · Crustecdysone
Code names: NSC-629484 · THE-7

Resolves to

Compound

UNII779A7KPL0YCAS5289-74-7ChEMBLCHEMBL224128ChEBI16587

Structure

InChIKeyNKDFYOWSKOHCCO-YPVLXUMRSA-NSMILES[H][C@@]1(CC[C@@]2(O)C3=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]4(C)[C@@]3([H])CC[C@]12C)[C@@](C)(O)[C@H](O)CCC(C)(C)O

Targets

P04201MAS1

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with 20-Hydroxyecdysone, and which of those have an active Phase 3 trial?

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