Potassium channel subfamily K member 18

BE0016097ProteinHumansKCNK18

K(+) channel that conducts outward and inward rectifying currents at depolarized and hyperpolarized membrane potentials, respectively. It is acted on by 9 drugs in DrugBank.

Gene name
KCNK18
UniProtKB entry
Q7Z418Swiss-Prot
Cellular location
Cell membrane
Residues / weight
384 residues · 43,671 Da
Also known as
TRESK · TRIK · TWIK-related individual potassium channel · TWIK-related spinal cord potassium channel

Resolves to

Protein
UniProtQ7Z418UniProt nameKCNKI_HUMAN
Gene
HGNCHGNC:19439NCBI Gene338567GeneCardsKCNK18
Pharmacology
KEGGhsa:338567
Drugs

What you can answer from here — as of September 03, 2024

9DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium channel subfamily K member 18, how selective are they, and which programs against it are still in active trials?

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