Oxidoreductases

Name
Oxidoreductases
Accession Number
DBCAT000142
Description

The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)

Drugs
DrugDrug Description
RasburicaseA recombinant form of urate-oxidase enzyme used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma.
LawsoneNot Available
BrequinarNot Available
TyrosinaseTyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states.[A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.[A231829, A231834, A231839] Within mammals, tyrosinase is...
PEG-uricaseInvestigated for use/treatment in hyperuricemia.
PegloticaseA recombinant uricase used for the treatment of chronic gout in adult patients refractory to conventional therapy.
Glucose oxidaseGlucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections.
Glyceraldehyde-3-Phosphate DehydrogenaseNot Annotated
Drugs & Drug Targets
DrugTargetType
RasburicaseUric acidtarget
BrequinarDihydroorotate dehydrogenase (quinone), mitochondrialtarget
PEG-uricaseUric acid degradation bifunctional proteintarget
PegloticaseUric acidtarget