Oxidoreductases
- Name
- Oxidoreductases
- Accession Number
- DBCAT000142
- Description
The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)
- Drugs
Drug Drug Description Rasburicase A recombinant form of urate-oxidase enzyme used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma. Lawsone Not Available Brequinar Not Available Tyrosinase Tyrosinase is a multi-copper-containing multifunctional metalloenzyme with 4 possible oxidation states.[A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.[A231829, A231834, A231839] Within mammals, tyrosinase is... PEG-uricase Investigated for use/treatment in hyperuricemia. Pegloticase A recombinant uricase used for the treatment of chronic gout in adult patients refractory to conventional therapy. Glucose oxidase Glucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections. Glyceraldehyde-3-Phosphate Dehydrogenase Not Annotated - Drugs & Drug Targets
Drug Target Type Rasburicase Uric acid target Brequinar Dihydroorotate dehydrogenase (quinone), mitochondrial target PEG-uricase Uric acid degradation bifunctional protein target Pegloticase Uric acid target