Vitamin E

Name

Vitamin E

Accession Number

DBCAT000373

Description

A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.

Drugs

Drug	Drug Description
Vitamin E	An antioxidant vitamin used in many skin creams and multivitamin preparations.
Tocopherol	Tocopherol can be used as a dietary supplement for patients with a deficit of vitamin E; this is mainly prescribed in the alpha form. Vitamin E deficiency is rare, and...
Tocotrienol	Tocotrienol has been investigated for the treatment of Cholesterol Lowering.
alpha-Tocopherol succinate	A form of vitamin E used to treat and prevent vitamin deficiencies.
D-alpha-Tocopherol acetate	A form of vitamin E used to treat and prevent vitamin deficiencies.
alpha-Tocopherol acetate	A form of vitamin E used to treat and prevent vitamin deficiencies.
Tocofersolan	A derivative of alpha tocopherol used to treat vitamin E deficiencies.
DL-alpha-Tocopherol	Not Annotated
gamma-Tocopherol	gamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics).
DL-alpha tocopheryl acetate	Not Annotated

Drugs & Drug Targets

Drug	Target	Type
Vitamin E	SEC14-like protein 4	target
Vitamin E	SEC14-like protein 3	target
Vitamin E	SEC14-like protein 2	target
Vitamin E	Nuclear receptor subfamily 1 group I member 2	target
Vitamin E	Protein kinase C beta type	target
Vitamin E	Arachidonate 5-lipoxygenase	target
Vitamin E	Protein kinase C alpha type	target
Vitamin E	Diacylglycerol kinase alpha	target
Vitamin E	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	target
Vitamin E	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	target
Vitamin E	Alpha-tocopherol transfer protein	carrier
Vitamin E	Glutathione S-transferase A2	enzyme
Vitamin E	Glutathione S-transferase P	enzyme
Vitamin E	Glutathione S-transferase omega-1	enzyme
Vitamin E	Glutathione S-transferase Mu 3	enzyme
Vitamin E	Glutamate--cysteine ligase catalytic subunit	enzyme
Vitamin E	NAD(P)H dehydrogenase [quinone] 1	enzyme
Vitamin E	Heme oxygenase 1	enzyme
Vitamin E	Superoxide dismutase [Cu-Zn]	enzyme
Vitamin E	Scavenger receptor class B member 1	transporter
Vitamin E	ATP-binding cassette sub-family A member 1	transporter
Vitamin E	Niemann-Pick C1-like protein 1	transporter
Vitamin E	ATP-binding cassette sub-family G member 1	transporter
Vitamin E	SEC14-like protein 2	carrier
Vitamin E	SEC14-like protein 3	carrier
Vitamin E	Phospholipid transfer protein	carrier
Vitamin E	Cytochrome P450 3A4	enzyme
Tocopherol	Free radicals	target
Tocopherol	Leukotriene-B(4) omega-hydroxylase 1	enzyme
Tocopherol	Cytochrome P450 3A4	enzyme
Tocopherol	Very low-density lipoprotein receptor	carrier
Tocopherol	Low-density lipoprotein receptor	carrier
Tocopherol	Alpha-tocopherol transfer protein	transporter
Tocopherol	SEC14-like protein 4	transporter
Tocopherol	SEC14-like protein 2	transporter
Tocopherol	SEC14-like protein 3	transporter
Tocopherol	Apolipoprotein B receptor	transporter
Tocopherol	Scavenger receptor class B member 1	transporter
Tocopherol	P-glycoprotein 1	transporter
alpha-Tocopherol succinate	SEC14-like protein 3	target
alpha-Tocopherol succinate	SEC14-like protein 2	target
alpha-Tocopherol succinate	Nuclear receptor subfamily 1 group I member 2	target
alpha-Tocopherol succinate	Protein kinase C beta type	target
alpha-Tocopherol succinate	Arachidonate 5-lipoxygenase	target
alpha-Tocopherol succinate	Protein kinase C alpha type	target
alpha-Tocopherol succinate	Alpha-tocopherol transfer protein	carrier
alpha-Tocopherol succinate	Glutathione S-transferase A2	enzyme
alpha-Tocopherol succinate	Glutathione S-transferase P	enzyme
alpha-Tocopherol succinate	Glutathione S-transferase omega-1	enzyme
alpha-Tocopherol succinate	Glutathione S-transferase Mu 3	enzyme
alpha-Tocopherol succinate	Glutamate--cysteine ligase catalytic subunit	enzyme
alpha-Tocopherol succinate	NAD(P)H dehydrogenase [quinone] 1	enzyme
alpha-Tocopherol succinate	Heme oxygenase 1	enzyme
alpha-Tocopherol succinate	Superoxide dismutase [Cu-Zn]	enzyme
alpha-Tocopherol succinate	Lung epithelial cells	target
alpha-Tocopherol succinate	Diacylglycerol kinase	target
D-alpha-Tocopherol acetate	SEC14-like protein 3	target
D-alpha-Tocopherol acetate	SEC14-like protein 2	target
D-alpha-Tocopherol acetate	Nuclear receptor subfamily 1 group I member 2	target
D-alpha-Tocopherol acetate	Protein kinase C beta type	target
D-alpha-Tocopherol acetate	Arachidonate 5-lipoxygenase	target
D-alpha-Tocopherol acetate	Protein kinase C alpha type	target
D-alpha-Tocopherol acetate	Alpha-tocopherol transfer protein	carrier
D-alpha-Tocopherol acetate	Glutathione S-transferase A2	enzyme
D-alpha-Tocopherol acetate	Glutathione S-transferase P	enzyme
D-alpha-Tocopherol acetate	Glutathione S-transferase omega-1	enzyme
D-alpha-Tocopherol acetate	Glutathione S-transferase Mu 3	enzyme
D-alpha-Tocopherol acetate	Glutamate--cysteine ligase catalytic subunit	enzyme
D-alpha-Tocopherol acetate	NAD(P)H dehydrogenase [quinone] 1	enzyme
D-alpha-Tocopherol acetate	Heme oxygenase 1	enzyme
D-alpha-Tocopherol acetate	Superoxide dismutase [Cu-Zn]	enzyme
alpha-Tocopherol acetate	Leukotriene-B(4) omega-hydroxylase 1	enzyme
alpha-Tocopherol acetate	Cytochrome P450 3A4	enzyme
alpha-Tocopherol acetate	Free radicals	target
alpha-Tocopherol acetate	Alpha-tocopherol transfer protein	transporter
alpha-Tocopherol acetate	SEC14-like protein 4	transporter
alpha-Tocopherol acetate	SEC14-like protein 2	transporter
alpha-Tocopherol acetate	SEC14-like protein 3	transporter
alpha-Tocopherol acetate	Apolipoprotein B receptor	transporter
alpha-Tocopherol acetate	Scavenger receptor class B member 1	transporter
alpha-Tocopherol acetate	P-glycoprotein 1	transporter
alpha-Tocopherol acetate	Very low-density lipoprotein receptor	carrier
alpha-Tocopherol acetate	Low-density lipoprotein receptor	carrier
Tocofersolan	P-glycoprotein 1	target
Tocofersolan	Leukotriene-B(4) omega-hydroxylase 1	enzyme
Tocofersolan	Alpha-tocopherol transfer protein	transporter
Tocofersolan	Scavenger receptor class B member 1	transporter
Tocofersolan	Niemann-Pick C1-like protein 1	transporter
Tocofersolan	ATP-binding cassette sub-family G member 5	transporter
Tocofersolan	ATP-binding cassette sub-family G member 8	transporter
Tocofersolan	ATP-binding cassette sub-family A member 1	transporter
Tocofersolan	SEC14-like protein 4	transporter
Tocofersolan	SEC14-like protein 2	transporter
Tocofersolan	SEC14-like protein 3	transporter
Tocofersolan	Apolipoprotein B receptor	transporter
Tocofersolan	Cytochrome P450 3A4	enzyme