- Lipoxygenase Inhibitors
- Accession Number
Compounds that bind to and inhibit that enzymatic activity of LIPOXYGENASES. Included under this category are inhibitors that are specific for lipoxygenase subtypes and act to reduce the production of LEUKOTRIENES.
Drug Drug Description Zileuton A leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma. Masoprocol Used for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated). Diethylcarbamazine An anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa. Benoxaprofen The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets... Atreleuton Atreleuton has been used in trials studying the treatment of Atherosclerosis and Coronary Artery Disease. Licofelone For the management of osteoarthritis. Veliflapon Veliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina). MK-886 MK-886 is an experimental inhibitor of leukotriene synthesis.
- Drugs & Drug Targets