Name
Triazoles
Accession Number
DBCAT000486
Description

Cyclic compounds that include atoms other than carbon in their ring structure.

Drugs
DrugDrug Description
AlbaconazoleAlbaconazole has been used in trials studying the basic science of Onychomycosis.
FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
VoriconazoleA triazole compound used to treat fungal infections.
SitagliptinAn oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.
LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
AnastrozoleA competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
ItraconazoleA triazole antifungal agent used to treat various fungal infections, such as blastomycosis and onychomycosis.
DeferasiroxAn iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin.
MaravirocA CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
TrapidilUsed in the treatment of chronic stable angina .
Drugs & Drug Targets
DrugTargetType
FluconazoleCytochrome P450 3A4enzyme
FluconazoleCytochrome P450 2C9enzyme
FluconazoleCytochrome P450 2C19enzyme
FluconazoleATP-dependent translocase ABCB1transporter
FluconazoleLanosterol 14-alpha demethylasetarget
FluconazoleCytochrome P450 3A5enzyme
VoriconazoleCytochrome P450 2C19enzyme
VoriconazoleCytochrome P450 3A4enzyme
VoriconazoleCytochrome P450 2C9enzyme
VoriconazoleFlavin-containing monooxygenase 1enzyme
VoriconazoleFlavin-containing monooxygenase 3enzyme
VoriconazoleCytochrome P450 3A5enzyme
VoriconazoleCytochrome P450 3A7enzyme
VoriconazoleProstaglandin G/H synthase 1enzyme
VoriconazoleLanosterol 14-alpha demethylasetarget
VoriconazoleCytochrome P450 2B6enzyme
SitagliptinDipeptidyl peptidase 4target
SitagliptinCytochrome P450 3A4enzyme
SitagliptinCytochrome P450 2C8enzyme
SitagliptinATP-dependent translocase ABCB1transporter
SitagliptinOrganic anion transporter 3transporter
LetrozoleAromatasetarget
LetrozoleCytochrome P450 3A4enzyme
LetrozoleCytochrome P450 2A6enzyme
LetrozoleAromataseenzyme
LetrozoleCytochrome P450 2C19enzyme
LetrozoleUDP-glucuronosyltransferase 2B7enzyme
LetrozoleAlbumincarrier
LetrozoleATP-dependent translocase ABCB1transporter
AnastrozoleAromatasetarget
AnastrozoleATP-dependent translocase ABCB1transporter
AnastrozoleCytochrome P450 3A4enzyme
AnastrozoleCytochrome P450 3A5enzyme
AnastrozoleCytochrome P450 2C8enzyme
AnastrozoleUDP-glucuronosyltransferase 1A4enzyme
AnastrozoleUDP-glucuronosyltransferase 1A3enzyme
AnastrozoleUDP-glucuronosyltransferase 2B7enzyme
AnastrozoleCytochrome P450 1A2enzyme
AnastrozoleCytochrome P450 2C9enzyme
ItraconazoleCytochrome P450 3A4enzyme
ItraconazoleCytochrome P450 3A5enzyme
ItraconazoleCytochrome P450 3A7enzyme
ItraconazoleCytochrome P450 2B6enzyme
ItraconazoleATP-dependent translocase ABCB1transporter
ItraconazoleCytochrome P450 1A1enzyme
ItraconazoleCytochrome P450 2E1enzyme
ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
ItraconazoleCytochrome P450 3A Subfamilyenzyme
ItraconazoleBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
ItraconazoleAlbumincarrier
ItraconazoleLanosterol 14-alpha demethylasetarget
ItraconazoleLanosterol 14-alpha demethylasetarget
DeferasiroxIrontarget
DeferasiroxCytochrome P450 3A4enzyme
DeferasiroxUDP-glucuronosyltransferase 1A1enzyme
DeferasiroxUDP-glucuronosyltransferase 1A3enzyme
DeferasiroxUDP-glucuronosyltransferase 1A9enzyme
DeferasiroxCytochrome P450 2C8enzyme
DeferasiroxCytochrome P450 1A2enzyme
MaravirocC-C chemokine receptor type 5target
MaravirocCytochrome P450 3A4enzyme
TrapidilPlatelet-derived growth factor receptor betatarget
TrapidilCyclic nucleotide phosphodiesterasetarget
TrapidilFibroblast growth factor receptor 3target