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Ensitrelvir

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Data Packages
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Identification

Generic Name
Ensitrelvir
DrugBank Accession Number
DB18834
Background

Ensitrelvir is under investigation in clinical trial NCT05605093 (Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)).

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 531.88
Monoisotopic: 531.114583
Chemical Formula
C22H17ClF3N9O2
Synonyms
Not Available
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

ATC Codes
J05AE16 — Ensitrelvir
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
PX665RAA3H
CAS number
2647530-73-0
InChI Key
QMPBBNUOBOFBFS-UHFFFAOYSA-N
InChI
InChI=1S/C22H17ClF3N9O2/c1-32-7-12-4-18(13(23)5-17(12)30-32)28-20-29-21(36)35(9-19-27-10-33(2)31-19)22(37)34(20)8-11-3-15(25)16(26)6-14(11)24/h3-7,10H,8-9H2,1-2H3,(H,28,29,36)
IUPAC Name
SMILES
CN1C=NC(CN2C(=O)NC(=NC3=CC4=CN(C)N=C4C=C3Cl)N(CC3=CC(F)=C(F)C=C3F)C2=O)=N1

References

General References
Not Available
ChemSpider
115007411
BindingDB
513874
ChEMBL
CHEMBL5183847
PDBe Ligand
7YY
Wikipedia
Ensitrelvir

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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3RecruitingTreatmentCoronavirus Disease 2019 (COVID‑19)1somestatusstop reasonjust information to hide
2RecruitingTreatmentCoronavirus Disease 2019 (COVID‑19)1somestatusstop reasonjust information to hide
2RecruitingTreatmentPost Acute Sequelae of COVID-19 / Post-Acute COVID-19 / Post-acute COVID-19 (PACS), or "Long COVID" Syndrome1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 26, 2024 16:47 / Updated at June 27, 2024 01:28