- Hydroxy Acids
- Accession Number
Organic compounds containing both the hydroxyl and carboxyl radicals.
Drug Drug Description Ascorbic acid A vitamin used to correct vitamin C deficiency and to increase the intestinal absorption of iron. Bacitracin A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Proparacaine A topical anesthetic used for ophthalmic practice. Oxybutynin An antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void. Trimetrexate A folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin. Bismuth subsalicylate An antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract. Phosphoenolpyruvate Not Available Iron sucrose An compound used as a source of iron in patients with iron deficiency anemia associated with chronic kidney disease (CKD). Mevalonic acid Not Available Salicylic acid An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Olsalazine An anti-inflammatory aminosalicylate used in the treatment of inflammatory bowel disease and ulcerative colitis. Magnesium salicylate An NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain. Salsalate A nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders. Choline magnesium trisalicylate Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. 2,4-Dihydroxybenzoic Acid Not Available 3,4-Dihydroxybenzoic Acid Not Available Balanol Not Available Dersalazine Investigated for use/treatment in inflammatory bowel disease. Phenyl aminosalicylate Not Annotated Triflusal A medication related to acetylsalicylic acid with antithrombotic effects used in the treatment of thromboembolic diseases. Methyl salicylate A topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons. Octisalate Ingredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer. Homosalate As ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer. Phenyl salicylate Pain and fever . Trolamine salicylate A medication used to relieve minor aches and pains of the muscles and joints. Glycol salicylate A salicylate used to treat mild to moderate muscle pain. Lifibrol Lifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia. Salirasib Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung. Benorilate Not Annotated Nifuroxazide An antibiotic indicated in the treatment of susceptible gastrointestinal infections. Imidazole salicylate Not Annotated Choline salicylate The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due... Thiosalicylic acid Not Annotated Ethyl salicylate A salicylate indicated in the treatment of sports related pain. Citrulline Used for nutritional supplementation, also for treating dietary shortage or imbalance. Trospium An antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). Aminosalicylic acid An aminosalicylate drug used to induce remission in ulcerative colitis. Calcium glucoheptonate A calcium supplement combined with calcium gluconate to treat hypocalcemia and maintain calcium levels. Acetohydroxamic acid A synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract. Zanamivir A neuraminidase inhibitor used to treat influenza A and B. Deferoxamine A chelating agent used to treat iron or aluminum toxicity and some blood transfusion dependent anemias. Clidinium A synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS. Marimastat For the treatment of various cancers Etacrynic acid A diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease. Balsalazide An aminosalicylate used to treat ulcerative colitis. Rabeprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. gamma-Hydroxybutyric acid Used as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance. Dimenoxadol Dimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. In the United... SC-74020 Not Available p-Hydroxymercuribenzoic acid Not Available Coprogen Not Available Benzhydroxamic Acid Not Available WAY-151693 Not Available 6-phospho-D-gluconic acid Not Available Vanillic acid A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13). Ilomastat Not Available Benzoylformic Acid Not Available Glutamine hydroxamate Not Available Vorinostat A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Not Available P-Anisic Acid Not Available D-Lactic acid A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Glycolic acid Not Available 4-phospho-D-erythronic acid Not Available 3-deoxy-D-arabino-hexonic acid Not Available Gallichrome Not Available 2-Keto-3-Deoxygluconate Not Available Glucaric acid Not Available 3-hydroxyanthranilic acid An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen. Hydracrylic acid Not Available Xylarohydroxamate Not Available 3-Dehydroquinic Acid Not Available 2-deoxy-2,3-dehydro-N-acetylneuraminic acid Not Available 4-hydroxybenzoic acid Not Available 3-Isopropylmalic Acid Not Available Trichostatin A Not Available Shikimate-3-Phosphate Not Available 3-Dehydroshikimate Not Available Bb-3497 Not Available Lactic acid An emollient and keratolytic used agent in various cosmetic products and used as an additive in various pharmaceutical products for its antibacterial properties. 4-Phospho-D-erythronohydroxamic acid Not Available 3-phospho-D-glyceric acid Not Available Gluconolactone A polyhydroxy acid used in the dissolution of calculi and used as an additive in various drug products to maintain consistency and other characteristics. Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Tienilic acid For the treatment of hypertension. Cyclandelate A vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis. Mepenzolate A postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued. Belinostat A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). PG-530742 Investigated for use/treatment in osteoarthritis. Sodium stibogluconate For the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment... Squalamine Investigated for use/treatment in ovarian cancer, lung cancer, and macular degeneration. Panobinostat A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents. Ammonium lactate An inorganic compound used for the symptomatic treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris and for temporary relief of itching associated with these conditions. Methenamine A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy. CGS-27023 Not Available 1-Naphthoxyacetic acid Not Available CTS-1027 CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection. Methyl vanillate Not Available Dehydroascorbic acid There is no approved indication for dehydroascorbic acid, but it has potential therapeutic use in patients with certain viruses and ischemic stroke. Teriflunomide A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. Adrafinil Used to relieve excessive sleepiness and inattention in elderly patients. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Clinofibrate Clinofibrate is a fibrate drug sold and marketed in Japan. Bromopride A substituted benzamide, closely related to metoclopramide, used as an antiemetic. Benactyzine Benactyzine is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety. Benactyzine is no longer widely used in medicine, although it is still a... Sodium oxybate A central nervous system depressant used to treat cataplexy and excessive daytime sleepiness (EDS) associated with narcolepsy. Trimebutine A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. Iproclozide For the treatment of depression. Propoxycaine Propoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures . It has been combined with procaine to accelerate its onset of action and... L-tartaric acid Tartaric Acid is primarily indicated in conditions like Antiscorbutic, Antiseptic. Calcium citrate An ingredient found in a variety of supplements and vitamins. Calcium gluconate An ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning. Manganese gluconate An ingredient found in a variety of supplements and vitamins. Copper gluconate An ingredient found in a variety of supplements and vitamins. Zinc gluconate An ingredient found in a variety of supplements and vitamins. Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Ascorbyl glucoside Not Annotated Ascorbyl phosphate Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in... Gleptoferron Colloid solution of ferric hydroxide, dextran & glucoheptonic acid. Tosedostat Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. Tosedostat is an inhibitor of the... Laninamivir octanoate Laninamivir octanoate has been used in trials studying the treatment of Asthma. Lanopepden Lanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases, Infectious, and Skin Infections, Bacterial. CUDC-101 CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others. CG-200745 Cg200745 has been used in trials studying the treatment of Solid Tumour. Propiverine An antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency. Ricolinostat Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer. R-306465 R306465 has been used in trials studying the treatment of Neoplasms. Resminostat Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others. Propyl Gallate Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects). Abexinostat Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase... Malic acid Malic acid has been used in trials studying the treatment of Xerostomia, Depression, and Hypertension. Laninamivir Laninamivir has been used in trials studying the treatment of Influenza. Pyroxamide Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others. Didox Didox has been used in trials studying the supportive care of Gastric Cancer. Quisinostat Quisinostat has been used in trials studying the treatment of Lymphoma, Neoplasms, Myelodysplastic Syndromes, and Advanced or Refractory Leukemia. Gluconic Acid An electrolyte supplement used in total parenteral nutrition. Mandelic acid Mandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically. Calcium lactate An ingredient found in a variety of nutritional products. Hexobendine Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has... Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Difemerine Not Annotated Mazaticol Not Annotated Poldine Not Annotated Alginic acid Indicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress . Bevonium Not Annotated Calcium pangamate Not Annotated Ethyl hydroxybenzoate Not Annotated Sodium tartrate It acts as an emulsifier and pH control agent in food products , . In the laboratory, it is used while performing the Karl Fischer equation, which is used to... Magnesium gluconate A mineral supplement used to treat or prevent hypomagnesemia. Meclofenoxate Not Annotated Reposal Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia. Bismuth subgallate A medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery. Calcium saccharate Pharmaceutic Aid (Stabilizer) Butylparaben Not Annotated Benzylparaben Benzylparaben is used in allergenic testing. Propylparaben Propylparaben is used in allergenic testing. Methylparaben Methylparaben is used in allergenic testing. L-Lactic acid Not Annotated Sodium ascorbate Not Available Calcium ascorbate Not Available Magnesium ascorbate Not Available Ferrous ascorbate A medication used to treat iron-deficiency anemia. Coleneuramide Coleneuramide is under investigation in clinical trial NCT00307749 (Safety and Efficacy of MCC-257 in the Treatment of Diabetic Polyneuropathy). Martinostat Martinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer). Salvianolic acid A Salvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet). Tefinostat Tefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)). GSK2256098 GSK2256098 is under investigation in clinical trial NCT02523014 (Vismodegib and FAK Inhibitor GSK2256098 in Treating Patients With Progressive Meningiomas). Caprylhydroxamic acid Not Annotated Lavendustin b Not Annotated WZB-117 Not Annotated Rosmarinic acid Not Annotated Dacinostat Dacinostat is a novel histone deacetylase inhibitor.
- Drugs & Drug Targets