Acids, Carbocyclic

Name
Acids, Carbocyclic
Accession Number
DBCAT000583
Description

Carboxylic acids that have a homocyclic ring structure in which all the ring atoms are carbon.

Drugs
DrugDrug Description
Tranexamic acidAn antifibrinolytic used to reduce or prevent hemorrhagic episodes, especially in the context of hyperfibrinolytic disorders.
SulpirideA selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia.
RemoxiprideAn discontinued atypical antipsychotic selective for dopamine D2 receptors.
MethylphenidateA stimulant used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
BacitracinA cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections.
FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
ProcaineA local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.
Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
DicyclomineAn antimuscarinic agent used to treat IBS.
ProparacaineA topical anesthetic used for ophthalmic practice.
SuprofenAn NSAID used to prevent pupil constriction in ocular surgery.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
CyclopentolateAn anticholinergic used to cause mydriasis and cycloplegia for diagnostic testing.
GabapentinAn anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures.
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
OxybutyninAn antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void.
BenzocaineA topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations.
MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
Bismuth subsalicylateAn antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
IohexolA contrast agent for intrathecal administration used in myelography and contrast enhancement for computerized tomography.
AmisulprideA dopamine D2 receptor antagonist used in the treatment of acute and chronic schizophrenia, and in the prevention and treatment of postoperative nausea and vomiting in adults.
NepafenacAn ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery.
Benzoyl peroxideAn antibacterial and anti-inflammatory agent used for the symptomatic treatment of mild to moderate acne vulgaris and rosacea.
AcalabrutinibA Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma.
CapmatinibA kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping.
BentiromideIndicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
TrimethobenzamideAn antiemetic used to treat postoperative nausea and vomiting and nausea associated with gastroenteritis.
Benzyl benzoateA topical treatment for scabies and lice.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
OlsalazineAn anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis.
Magnesium salicylateAn NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain.
SalsalateA nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
RoflumilastA selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis.
Benzene Hexacarboxylic AcidNot Available
PiclamilastPiclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as...
3-(5-amino-7-hydroxy-(1,2,3)triazolo(4,5-d)pyrimidin-2-yl)benzoic acidNot Available
GabaculineNot Available
4-guanidinobenzoic acidNot Available
Pyromellitic AcidNot Available
2,4-Dihydroxybenzoic AcidNot Available
Arotinoid acidArotinoid acid is a retinoic acid analog which acts as a selective RAR agonist.
3-MethoxybenzamideNot Available
4-FluorobenzylamineNot Available
GW-3965GW-3965 is a liver X receptor ligand.
CilomilastInvestigated for use/treatment in chronic obstructive pulmonary disease (COPD).
3,4-Dihydroxybenzoic AcidNot Available
BalanolNot Available
1-(4-Amidinophenyl)-3-(4-Chlorophenyl)UreaNot Available
AcedobenNot Available
RenzaprideFor the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
ItoprideAn acetylcholine esterase inhibitor and dopamine D2 receptor antagonist used to treat symptoms of functional dyspepsia such as nausea and vomiting.
TamibaroteneInvestigated for use/treatment in leukemia (unspecified).
ApadenosonInvestigated for use/treatment in cardiovascular disorders and inflammatory disorders (unspecified).
ADL5859Investigated for use/treatment in pain (acute or chronic).
INCB3284Investigated for use/treatment in inflammatory disorders (unspecified).
Atl146eInvestigated for use/treatment in inflammatory disorders (unspecified).
APD791For the treatment and prophylaxis of arterial thrombosis.
VX-765Investigated for use/treatment in inflammatory disorders (unspecified) and psoriasis and psoriatic disorders.
NaronaprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
SB-743921Investigated for use/treatment in cancer/tumors (unspecified) and lymphoma (non-hodgkin's).
SLx-4090Investigated for use/treatment in hyperlipidemia.
SNX-5422Investigated for use/treatment in cancer/tumors (unspecified).
IspinesibInvestigated for use/treatment in breast cancer, lung cancer, solid tumors, renal cell carcinoma, pediatric indications, ovarian cancer, and head and neck cancer.
SolabegronInvestigated for use/treatment in diabetes mellitus type 2, irritable bowel syndrome (IBS), and urinary incontinence.
EltrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
DersalazineInvestigated for use/treatment in inflammatory bowel disease.
OnalespibInvestigated for use/treatment in cancer/tumors (unspecified).
TucidinostatInvestigated for use/treatment in cancer/tumors (unspecified).
FK-960Investigated for use/treatment in dementia, alzheimer's disease, schizophrenia and schizoaffective disorders, and memory loss.
AplavirocInvestigated for use/treatment in HIV infection.
TonabersatInvestigated for use/treatment in migraine and cluster headaches.
SaredutantInvestigated for use/treatment in depression and anxiety disorders.
LixivaptanInvestigated for use/treatment in hyponatremia and congestive heart failure.
Phenyl aminosalicylateNot Annotated
PD-0325901PD-0325901 has been used in trials studying the treatment and basic science of Melanoma, Solid Tumour, Solid Tumors, Advanced Cancer, and Breast Neoplasms, among others.
PH-797804PH-797804 has been investigated for the treatment of Osteoarthritis.
PlatensimycinNot Available
Prephenic acidNot Available
4-(Dimethylamino)benzoic acidNot Available
SalicylamideSalicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin....
CinitaprideA benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying.
TriflusalA medication related to acetylsalicylic acid with antithrombotic effects used in the treatment of thromboembolic diseases.
EnzalutamideAn androgen receptor inhibitor used to treat castration-resistant prostate cancer and metastatic castration-sensitive prostate cancer.
EtamivanEtamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States.
AmylocaineA local and topical anaesthetic agent.
Methyl salicylateA topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
OctisalateIngredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer.
HomosalateAs ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer.
Phenyl salicylatePain and fever .
Trolamine salicylateA medication used to relieve minor aches and pains of the muscles and joints.
ButambenAnesthesia of mucus membranes other than the eyes.
Padimate APadimate A is an ester derivative of PABA and an ingredient in some sunscreens. It absorbs ultraviolet rays thereby preventing sunburn, however, its chemical structure and behaviour is similar to...
Glycol salicylateA salicylate used to treat mild to moderate muscle pain.
LufenuronLufenuron is used in veterinary for the control of flea.
ButacaineNot Annotated
MasitinibMasitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the...
TricaineTricaine (as tricaine methanesulfonate) is white powder used for anesthesia, sedation, or euthanasia of fish. It is also the only anesthetic licensed in the United States for use in fin...
Padimate OAn ingredient used in sunscreens to absorb UV radiation.
CandoxatrilatA dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. A potent inhibitor of neutral endopeptidase (NEP,...
AZD-4877AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others.
MosaprideA prokinetic 5-HT4 receptor agonist used to stimulate gastric motility.
NavarixinNavarixin has been investigated for the treatment of Asthma.
MomelotinibMomelotinib has been used in trials studying the treatment of Polycythemia Vera, Primary Myelofibrosis, Post-Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis (PMF), among others.
DanusertibDanusertib has been used in trials studying the treatment of Leukemia.
DanegaptideDanegaptide has been investigated for the treatment of Focus of Study is STEMI.
MocetinostatMocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.
EntinostatEntinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic...
FlumatinibFlumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic.
VistusertibVistusertib is under investigation for the treatment of Advanced Gastric Adenocarcinoma.
TasisulamTasisulam has been used in trials studying the treatment and basic science of Melanoma, Lymphoma, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.
AxelopranAxelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation.
TecovirimatAn antiviral medication used to treat smallpox.
CE-224535CE-224535 has been used in trials studying the treatment of Osteoarthritis.
N-6022N6022 has been used in trials studying the treatment of Asthma and Cystic Fibrosis.
BalicatibBalicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis.
DefactinibDefactinib has been investigated for the treatment of Malignant Pleural Mesothelioma.
DarexabanDarexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.
TacedinalineTacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer.
BavisantBavisant has been used in trials studying the basic science and treatment of Alcoholism, Pharmacokinetics, Drug Interactions, Attention Deficit Hyperactivity Disorder, and Attention Deficit Disorders With Hyperactivity.
RadotinibRadotinib is indicated for the treatment of different types of cancer, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other Bcr-Abl tyrosine-kinase inhibitors, such...
IdasanutlinIdasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.
LY-2456302Ly2456302 has been used in trials studying the health services research and basic science of Anxiety Disorders and Alcohol Dependence.
BetrixabanA Factor Xa inhibitor used for prophylaxis of venous thromboembolism in hospitalized patients.
CI-1040CI-1040 has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Breast Neoplasms, Pancreatic Cancer, and Colorectal Cancer, among others.
LifibrolLifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia.
AcotiamideAcotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.
BI-671800Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial.
MK-5108MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors.
MK-0686MK0686 has been used in trials studying the treatment of Osteoarthritis, Pain, Postoperative, and Neuralgia, Postherpetic.
AZD-9056AZD9056 has been used in trials studying the basic science and treatment of Rheumatoid Arthritis.
EtripamilEtripamil has been used in trials studying the treatment of Paroxysmal Supraventricular Tachycardia (PSVT).
JNJ-41443532JNJ-41443532 has been used in trials studying the basic science and treatment of Diabetes Mellitus, Type 2.
SalirasibSalirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
RelenoprideRelenopride has been used in trials studying the treatment of Chronic Idiopathic Constipation.
CHF-6001CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease.
TecarfarinTecarfarin has been used in trials studying the prevention of Thrombosis and Thromboembolism.
EtalocibEtalocib has been used in trials studying the treatment of Pancreatic Cancer, Carcinoma, Non-Small-Cell Lung, and Unspecified Adult Solid Tumor, Protocol Specific.
DA-6886DA-6886 has been used in trials studying the treatment of Irritable Bowel Syndrome.
RO-4987655RO4987655 has been used in trials studying the treatment of Neoplasms.
GranotapideGranotapide has been used in trials studying the treatment of Type II Diabetes Mellitus.
LY-2300559Ly2300559 has been used in trials studying the prevention of Migraine Headache.
TucaresolTucaresol has been used in trials studying the treatment of HIV Infections.
AminaphthoneA medication that inhibits erythrocyte aggregation in capillaries, improving venous return for the treatment of capillary fragility.
CEP-37440CEP-37440 has been used in trials studying the treatment of Solid Tumors.
SCYX-7158SCYX-7158 has been used in trials studying the treatment of Trypanosomiasis, Parasitic Diseases, Protozoan Infections, and Trypanosomiasis, African.
4SC-2024SC-202 has been used in trials studying the treatment of Advanced Hematologic Malignancies.
Iobenzamic acidNot Annotated
CleboprideA dopamine antagonist used to treat symptoms associated with functional gastrointestinal disorders. Clebopride may also be used to treat nausea and vomiting associated with chemotherapy.
RociverineAn antispasmodic indicated in the treatment of urinary, gastrointestinal, and biliary tract spasms.
BenorilateNot Annotated
NifuroxazideAn antibiotic indicated in the treatment of susceptible gastrointestinal infections.
Imidazole salicylateNot Annotated
IniparibNot Annotated
NetarsudilA rho kinase inhibitor used to reduce intraocular pressure in patients with open angle glaucoma or ocular hypertension.
Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
Thiosalicylic acidNot Annotated
BrovanexineNot Annotated
LGD-6972LGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus).
TAS-116TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors).
GalicaftorGalicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without...
SelonsertibSelonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).
GTX-758GTX-758 is under investigation in clinical trial NCT01420861 (GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer).
DifamilastDifamilast is under investigation in clinical trial NCT01702181 (A Safety Study to Evaluate the Use and Effectiveness of a Topical Ointment to Treat Adults With Atopic Dermatitis).
FallyprideFallypride is under investigation in clinical trial NCT02310360 (Striatal and Extra-striatal Dopamine Release in Response to Food in Healthy Humans).
ONO-8539ONO-8539 is under investigation in clinical trial NCT01707901 (A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease).
AcebilustatAcebilustat is under investigation in clinical trial NCT01748838 (Phase 1 Study Assessing the Safety and Tolerability of CTX-4430).
AZD-9977AZD-9977 is under investigation in clinical trial NCT03843060 (A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers).
GiripladibGiripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee).
AcumapimodAcumapimod is under investigation in clinical trial NCT02926326 (The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers).
Octyl triazoneNot Annotated
Ethyl salicylateA salicylate indicated in the treatment of sports related pain.
TAK-715TAK-715 is under investigation in clinical trial NCT00760864 (Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis).
CinaciguatCinaciguat is under investigation in clinical trial NCT01067859 (A Phase Iib Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 ΜG/h, 10 ΜG/h) Given Intravenously to Patients...
AcetyldinalineAcetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).
FenpyroximateFenpyroximate is under investigation in clinical trial NCT02533336 (The Effectiveness of Non-pyrethroid Insecticide-treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania).
TrospiumAn antimuscarinic agent used to treat the symptoms of overactive bladder (OAB).
Aminosalicylic acidAn aminosalicylate drug used to induce remission in ulcerative colitis.
DiatrizoateAn injected contrast agent used in radiology.
Aminohippuric acidA hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system.
NitisinoneA hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods.
FenoprofenAn anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
CisaprideA medication used to treat heartburn associated with GERD.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
ClidiniumA synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS.
BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
OxybuprocaineA local anesthetic used in ophthalmology.
Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
ProcainamideA medication used to treat life threatening ventricular arrhythmias.
ThalidomideA medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.
ChloroprocaineA local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, or spinal anesthesia.
ProcarbazineAn antineoplastic agent indicated for the treatment of stage III and stage IV Hodgkin's disease in combination with other chemotherapeutic agents.
MoclobemideA monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder.
IodixanolA contrast agent used during coronary angiography, particularly in patients with renal dysfunction.
LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
BezafibrateA lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder.
DiethyltryptamineDiethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.
DimenoxadolDimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. In the United...
EmbutramideNot Available
MetrizamideMetrizamide is used for lumbar, thoracic, cervical, and total columnar myelography to determine the presence of abnormalities in the spinal column, spinal canal, and central nervous system (CNS) as well...
DeferasiroxAn iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin.
p-Hydroxymercuribenzoic acidNot Available
3,4-Dihydroxycinnamic AcidNot Available
3-phenylpropionic acidNot Available
Vanillic acidA flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).
O-SuccinylbenzoateNot Available
Flufenamic acidAn analgesic drug used to relieve pain associated with rheumatoid diseases.
Benzoylformic AcidNot Available
Aminobenzoic acidA drug used to reduce the progression of penile deviation in Peyronie's Disease in adults.
JE-2147Not Available
Compound 18Not Available
Phthalic AcidNot Available
Isochorismic AcidNot Available
P-Anisic AcidNot Available
Mant-AdpNot Available
KB-141An anticholesteremic agent.
Diphenylacetic acidNot Available
3-hydroxyanthranilic acidAn oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
p-Chlorobenzoic acidNot Available
Benzoic acidAn antimicrobial food additive.
3-Dehydroquinic AcidNot Available
Phenylpyruvic acidNot Available
Phloretic acidNot Available
p-Coumaric acidNot Available
Anthranilic acidNot Available
4-hydroxybenzoic acidNot Available
Shikimate-3-PhosphateNot Available
3-DehydroshikimateNot Available
Niflumic acidA cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.
IodipamideA contrast agent used in cholangiography and cholecystography.
OxeladinWithdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity.
CyclandelateA vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis.
MepenzolateA postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued.
DarusentanFor the treatment of congestive heart failure and hypertension.
RonacaleretPost-menopausal women with osteoporosis
OMS-103HPInvestigated for use/treatment in inflammatory disorders (unspecified), knee replacement, orthopedic surgery, and pain (acute or chronic).
PX-478Investigated for use/treatment in cancer/tumors (unspecified).
TanomastatInvestigated for use/treatment in pancreatic cancer, lung cancer, ovarian cancer, and osteoarthritis.
AmbrisentanA selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications.
DeclopramideInvestigated for use/treatment in colorectal cancer and inflammatory bowel disease.
TicaloprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
ErtiprotafibInvestigated for use/treatment in diabetes mellitus type 2.
RagaglitazarInvestigated for use/treatment in diabetes mellitus type 2.
TesaglitazarInvestigated for use/treatment in diabetes mellitus type 2.
AxitinibAn oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
MethenamineA urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy.
Phenylbutyric acidAn agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy.
m-Hydroxyhippuric acidNot Available
Isoferulic acidNot Available
p-Nitrophenylacetic acidNot Available
AcifluorfenAcifluorfen is a protoporphyrinogen oxidase inhibitor.
FelbinacNot Available
TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acidNot Available
4-Hydroxyphenylpyruvic acidNot Available
Ferulic acidNot Available
Homogentisic acidNot Available
PuromycinPuromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...
4-(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACIDNot Available
Sinapic acidSinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. It is also a constituent of propolis.
2-HydroxybenzalpyruvateNot Available
Methyl vanillateNot Available
N-CaffeoyltyramineNot Available
Glycerol phenylbutyrateA nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions.
PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
Iotroxic acidIotroxic acid is a contrast medium molecule.
IopamidolA diagnostic imaging agent used for angiography throughout the cardiovascular system.
IodamideIodamide is a contrast medium molecule that is no longer marketed in the United States.
IndoraminIndoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
IndoprofenA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
GlafenineAn anthranilic acid derivative with analgesic properties used for the relief of all types of pain. Glafenine is withdrawn from the American market.
FloctafenineAn anti-inflammatory analgesic used to manage mild to moderate acute pain.
FenbufenFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
EtofenamateAn NSAID used to treat muscle and joint pain.
BromoprideA substituted benzamide, closely related to metoclopramide, used as an antiemetic.
BenactyzineBenactyzine is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety. Benactyzine is no longer widely used in medicine, although it is still a...
TetracaineA local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures.
EugenolA phenol used for the temporary relief of toothaches.
TrimebutineA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
Iothalamic acidA diagnostic contrast agent used in various medical imaging procedures, such as angiography, arthrography, and computed tomographic scans.
IoversolA diagnostic contrast agent used in various medical imaging procedures, such as angiography, urography, and computed tomographic scans.
IoxilanA diagnostic contrast agent used in various medical imaging procedures, such as angiography, urography, and computed tomographic scans.
IopromideAn X-ray contrast agent used during various types of imaging tests such as angiography and contrast computed tomography (CT) imaging tests.
LoxoprofenAn NSAID used to treat pain and inflammation in musculoskeletal conditions.
DexibuprofenA pharmacologically active enantiomer of racemic ibuprofen (NSAID) used to treat pain and inflammation.
DexketoprofenAn NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain.
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
Phenylacetic acidAn agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle.
MorniflumateAn NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems.
Ioxaglic acidA tri-iodinated benzoate contrast agent used in various radiological procedures including angiography, phlebography, urography, computed tomography (CT), and hysterosalpingography.
Procaine benzylpenicillinA local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection.
PropoxycainePropoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures . It has been combined with procaine to accelerate its onset of action and...
Metrizoic acidFor use as a contrast medium .
Acetrizoic acidAcetrizoic acid indication was to be used as a contrast agent for X-ray. Some information indicates its nephrotropic property as one of the characteristics for the utilization of acetrizoic acid....
MeglumineAn amino sugar found in iodinated contrast media.
IotrolanNonionic, isotonic contrast medium designed for intrathecal use.
OctinoxateA sunscreen agent found in sunscreens that absorbs UV rays.
MeradimateAn ingredient used in sunscreens to absorb UV radiation.
AmiloxateIndicated as an active sunscreen agent.
DiethyltoluamideAn insect repellant, also known as DEET.
Ethyl ferulateNot Annotated
NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
RobenacoxibRobenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs.
ZoaleneDinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.
IferanserinIferanserin has been investigated for the treatment of Hemorrhoids.
IomeprolAn iodine-based X-ray contrast agent.
ArhalofenateArhalofenate has been investigated for the treatment of Gout and Hyperuricemia.
Chlorogenic AcidChlorogenic Acid has been used in trials studying the treatment of Advanced Cancer and Impaired Glucose Tolerance.
CC-220CC-220 has been used in trials studying the treatment of Systemic Lupus Erythematosus.
PelubiprofenPelubiprofen has been investigated for the treatment of Chronic Back Pain.
GDC-0810ARN-810 has been used in trials studying the basic science and treatment of Breast Cancer.
VidupiprantVidupiprant has been used in trials studying the treatment and basic science of Asthma.
PropiverineAn antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency.
IobitridolAn iodine-based contrast agent used with X-ray or CT imaging.
PF-03635659Pf03635659 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
IoforminolIoforminol has been used in trials studying the diagnostic of Cardio Renal Safety in High-risk Elderly Subjects Undergoing a Coronary CATH With or Without PCI.
Propyl GallatePropyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).
RacloprideRaclopride has been used in trials studying Parkinson Disease.
IndobufenA reversible platelet aggregation inhibitor used to prevent coronary and peripheral artery occlusion.
AZD-3043AZD3043 has been used in trials studying the treatment and basic science of Safety, Sedation, Tolerability, and Pharmacokinetics.
NaveglitazarNaveglitazar has been used in trials studying the treatment of Diabetes Mellitus, Non-Insulin-Dependent.
BeloranibBeloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others.
E-6005E6005 has been used in trials studying the treatment of Atopic Dermatitis.
AtaciguatAtaciguat has been investigated for the basic science of Aortic Valve Stenosis.
XL-888XL888 has been used in trials studying the treatment of Cancer and Melanoma.
TiaprideA dopamine D2 and D3 receptor antagonist indicated in the treatment of chorea in Huntington's disease, as well as agitation and anxiety in the elderly or with acute or chronic alcoholism.
SaroglitazarSaroglitazar has been investigated for the treatment of Fatty Liver.
LusutrombopagA medication used to treat thrombocytopenia in patients with chronic liver disease scheduled to have a procedure.
AlclofenacAlclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies.
Mandelic acidMandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically.
PropanididAn intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)
HexobendineHexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has...
SultoprideSultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics .
PicotamideA platelet aggregation inhibitor indicated in the treatment of myocardial infarction, thrombosis, cerebrovascular disorders, pulmonary emboli, and atherosclerosis.
DimethylphthalateNot Annotated
PiperidolateNot Annotated
DifemerineNot Annotated
Ioxitalamic acidA contrast agent used for CT scans of the abdomen and pelvis.
PoldineNot Annotated
VeraliprideNot Annotated
Iodoxamic acidRadiopaque medium used in the diagnosis of gall bladder & bile duct diseases, usually as meglumine salt.
BevoniumNot Annotated
Ethyl hydroxybenzoateNot Annotated
Ioglicic acidNot Annotated
DibutylphthalateNot Annotated
PirprofenNot Annotated
ButamirateA cough suppressant.
Ioglycamic acidNot Annotated
Iocarmic acidNot Annotated
TilidineA synthetic opioid indicated in the treatment of severe pain.
IopentolIopentol is used as a contrast medium.
Bismuth subgallateA medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
ButylparabenNot Annotated
BenzylparabenBenzylparaben is used in allergenic testing.
PropylparabenPropylparaben is used in allergenic testing.
IsoeugenolIsoeugenol is approved by the FDA for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in...
MethylparabenMethylparaben is used in allergenic testing.
AZD-8848AZD-8848 is under investigation in clinical trial NCT01818869 (To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses AZD8848 in Healthy Subjects).
CEP-9722CEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).
AZD-6482AZD-6482 is under investigation in clinical trial NCT00688714 (Study to Investigate Safety and Tolerability of a Single Dose of AZD6482).
AZD-9496AZD-9496 is under investigation in clinical trial NCT02248090 (AZD9496 First Time in Patients Ascending Dose Study).
Salvianolic acid ASalvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet).
Iodohippuric acidIodohippuric acid is under investigation in clinical trial NCT02599844 (Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults).
CinoxateNot Annotated
AdiphenineNot Annotated
AmfenacNot Annotated
Levosulpirideindicated to treat dyspepsia, symptoms of Meniere's syndrome, and second line in the treatment of drug-induced nausea and vomiting.
GED-0507-34-LevoGED-0507-34-Levo is under investigation in clinical trial NCT02808390 (Efficacy and Safety Study of Ged-0507-34-levo for Treatment of UC).
VicagrelVicagrel is under investigation in clinical trial NCT03599284 (The Efficacy, Safety and Pharmacokinetic of Antiplatelet Therapy for Vicagrel).
Lavendustin bNot Annotated
WZB-117Not Annotated
Methyl 2,5-dihydroxycinnamateNot Annotated
Drugs & Drug Targets
DrugTargetType
Tranexamic acidPlasminogentarget
SulpirideDopamine D2 receptortarget
SulpirideDopamine D3 receptortarget
SulpirideCholinesteraseenzyme
SulpirideCarbonic anhydrase 2target
SulpirideCarbonic anhydrase 3target
SulpirideSerum albumincarrier
SulpirideSolute carrier family 22 member 1transporter
SulpirideSolute carrier family 22 member 2transporter
SulpirideMultidrug and toxin extrusion protein 1transporter
SulpirideMultidrug and toxin extrusion protein 2transporter
SulpirideDopamine D4 receptortarget
SulpirideSolute carrier family 22 member 3transporter
SulpirideP-glycoprotein 1transporter
SulpirideATP-binding cassette sub-family G member 2transporter
RemoxiprideDopamine D2 receptortarget
RemoxiprideDopamine D4 receptortarget
Remoxipride5-hydroxytryptamine receptor 2Atarget
RemoxiprideSigma non-opioid intracellular receptor 1target
RemoxiprideDopamine D3 receptortarget
RemoxiprideCytochrome P450 2D6enzyme
Remoxipridealpha1-acid glycoproteincarrier
RemoxiprideCytochrome P450 1A2enzyme
RemoxiprideCytochrome P450 2B1enzyme
RemoxiprideCytochrome P450 3A Subfamilyenzyme
MethylphenidateSodium-dependent dopamine transportertarget
MethylphenidateSodium-dependent noradrenaline transportertarget
MethylphenidateCarboxylesteraseenzyme
Methylphenidate5-hydroxytryptamine receptor 1Atarget
LenalidomideProstaglandin G/H synthase 2target
LenalidomideTumor necrosis factor ligand superfamily member 11target
LenalidomideCadherin-5target
LenalidomideProtein cereblontarget
LenalidomideP-glycoprotein 1transporter
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
BacitracinAlpha-2-macroglobulintarget
BacitracinInsulin-degrading enzymetarget
BacitracinC55-isoprenyl pyrophosphatetarget
BacitracinBacitracin transport ATP-binding protein BcrAtransporter
BacitracinBacitracin transport permease protein BCRBtransporter
BacitracinBacitracin transport permease protein BcrCtransporter
FurosemideSolute carrier family 12 member 1target
FurosemideSerum albumincarrier
FurosemideSolute carrier family 22 member 6transporter
FurosemideSolute carrier family 22 member 5transporter
FurosemideSolute carrier family 22 member 8transporter
FurosemideCanalicular multispecific organic anion transporter 1transporter
FurosemideSolute carrier organic anion transporter family member 2A1transporter
FurosemideSolute carrier family 22 member 11transporter
Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
FurosemideCarbonic anhydrase 2target
FurosemideUDP-glucuronosyltransferase 1-1enzyme
FurosemideThyroxine-binding globulincarrier
FurosemideG-protein coupled receptor 35target
ProcaineSodium channel protein type 10 subunit alphatarget
ProcaineGlutamate receptor ionotropic, NMDA 3Atarget
Procaine5-hydroxytryptamine receptor 3Atarget
ProcaineSodium-dependent dopamine transportertarget
ProcaineNeuronal acetylcholine receptor subunit alpha-2target
ProcaineCholinesteraseenzyme
ProcaineDNA (cytosine-5)-methyltransferase 1target
ProcaineCalcium-activated potassium channeltarget
ProcaineCytosolic phospholipase A2target
Procaine60 kDa lysophospholipasetarget
ProcaineMonoamine oxidasetarget
ProcaineSodium-dependent dopamine transportertransporter
ProcaineSodium-dependent noradrenaline transportertransporter
ProcaineSodium-dependent serotonin transportertransporter
ProcaineDNA (cytosine-5)-methyltransferase 3Atarget
Mefenamic acidProstaglandin G/H synthase 2target
Mefenamic acidProstaglandin G/H synthase 1target
Mefenamic acidCytochrome P450 2C9enzyme
Mefenamic acidCytochrome P450 2C8enzyme
Mefenamic acidSerum albumincarrier
Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
Mefenamic acidCytochrome P450 1A2enzyme
Mefenamic acidUDP-glucuronosyltransferase 2B7enzyme
DicyclomineMuscarinic acetylcholine receptor M1target
DicyclomineMuscarinic acetylcholine receptor M2target
DicyclomineMuscarinic acetylcholine receptor M3target
ProparacaineSodium channel protein type 10 subunit alphatarget
SuprofenProstaglandin G/H synthase 1target
SuprofenProstaglandin G/H synthase 2target
SuprofenCytochrome P450 2C9enzyme
SuprofenUDP-glucuronosyltransferase 1-1enzyme
SuprofenSolute carrier family 22 member 12transporter
SuprofenUDP-glucuronosyltransferase 2B7enzyme
SuprofenSerum albumincarrier
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidP-glycoprotein 1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acid78 kDa glucose-regulated proteintarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidSolute carrier family 22 member 8transporter
Acetylsalicylic acidSialidase-1target
CyclopentolateMuscarinic acetylcholine receptor M1target
CyclopentolateCholinesteraseenzyme
GabapentinAdenosine receptor A1target
GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-1target
GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-2target
GabapentinBranched-chain-amino-acid aminotransferase, cytosolicenzyme
GabapentinLarge neutral amino acids transporter small subunit 1transporter
GabapentinVoltage-dependent N-type calcium channeltarget
GabapentinPotassium voltage-gated channel subfamily KQT member 3target
GabapentinPotassium voltage-gated channel subfamily KQT member 5target
IbuprofenProstaglandin G/H synthase 1target
IbuprofenProstaglandin G/H synthase 2target
IbuprofenCytochrome P450 2C9enzyme
IbuprofenSerum albumincarrier
IbuprofenMultidrug resistance-associated protein 4transporter
IbuprofenMultidrug resistance-associated protein 1transporter
IbuprofenSolute carrier organic anion transporter family member 1A2transporter
IbuprofenSolute carrier family 22 member 6transporter
IbuprofenSolute carrier family 22 member 8transporter
IbuprofenSolute carrier family 22 member 11transporter
IbuprofenSolute carrier organic anion transporter family member 2B1transporter
IbuprofenP-glycoprotein 1transporter
IbuprofenUDP-glucuronosyltransferase 1-3enzyme
IbuprofenUDP-glucuronosyltransferase 1-9enzyme
IbuprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenUDP-glucuronosyltransferase 2B7enzyme
IbuprofenCytochrome P450 2C8enzyme
IbuprofenCytochrome P450 2C19enzyme
IbuprofenApoptosis regulator Bcl-2target
IbuprofenThrombomodulintarget
IbuprofenFatty acid-binding protein, intestinaltarget
IbuprofenPeroxisome proliferator-activated receptor gammatarget
IbuprofenCystic fibrosis transmembrane conductance regulatortarget
IbuprofenPeroxisome proliferator-activated receptor alphatarget
IbuprofenPlatelet glycoprotein Ib alpha chaintarget
IbuprofenProtein S100-A7target
IbuprofenAlpha-methylacyl-CoA racemaseenzyme
IbuprofenCytochrome P450 3A4enzyme
OxybutyninMuscarinic acetylcholine receptor M1target
OxybutyninMuscarinic acetylcholine receptor M2target
OxybutyninMuscarinic acetylcholine receptor M3target
OxybutyninCytochrome P450 3A4enzyme
OxybutyninCytochrome P450 2C8enzyme
OxybutyninCytochrome P450 2D6enzyme
OxybutyninCytochrome P450 3A5enzyme
OxybutyninAlpha-1-acid glycoprotein 1carrier
OxybutyninSerum albumincarrier
BenzocaineSodium channel protein type 10 subunit alphatarget
BenzocaineP-glycoprotein 1transporter
BenzocaineLiver carboxylesterase 1enzyme
BenzocaineCytochrome P450 1A2enzyme
BenzocaineCytochrome P450 2B6enzyme
BenzocaineCytochrome P450 2C19enzyme
BenzocaineCytochrome P450 2D6enzyme
BenzocaineCytochrome P450 2E1enzyme
BenzocaineSerum albumincarrier
Benzocainealpha1-acid glycoproteincarrier
MetoclopramideMuscarinic acetylcholine receptor M1target
MetoclopramideDopamine D2 receptortarget
MetoclopramideCytochrome P450 2D6enzyme
Metoclopramide5-hydroxytryptamine receptor 4target
Metoclopramide5-hydroxytryptamine receptor 3Atarget
MetoclopramideCytochrome P450 3A4enzyme
MetoclopramideCytochrome P450 1A2enzyme
MetoclopramideP-glycoprotein 1transporter
MetoclopramideAlpha-1-acid glycoprotein 1carrier
Bismuth subsalicylateSerum albumincarrier
Bismuth subsalicylateSerotransferrincarrier
AmisulprideDopamine D2 receptortarget
AmisulprideDopamine D3 receptortarget
Amisulpride5-hydroxytryptamine receptor 7target
Amisulpride5-hydroxytryptamine receptor 2Atarget
AmisulprideErythrocytecarrier
AmisulprideMultidrug and toxin extrusion protein 1transporter
AmisulprideMultidrug and toxin extrusion protein 2transporter
AmisulprideP-glycoprotein 1transporter
AmisulprideATP-binding cassette sub-family G member 2transporter
AmisulprideSolute carrier family 22 member 1transporter
AmisulprideMu-type opioid receptortarget
AmisulprideDelta-type opioid receptortarget
AmisulprideKappa-type opioid receptortarget
NepafenacProstaglandin G/H synthase 1target
NepafenacProstaglandin G/H synthase 2target
Benzoyl peroxideCatalaseenzyme
Benzoyl peroxideCatalasetarget
Benzoyl peroxideArginine decarboxylasetarget
Benzoyl peroxideProtein kinase Ctarget
Benzoyl peroxideGlutathione peroxidasetarget
Benzoyl peroxideSuperoxide Dismutasestarget
AcalabrutinibTyrosine-protein kinase BTKtarget
AcalabrutinibCytochrome P450 3A4enzyme
AcalabrutinibCytochrome P450 3A5enzyme
AcalabrutinibCytochrome P450 3A Subfamilyenzyme
AcalabrutinibSerum albumincarrier
Acalabrutinibalpha1-acid glycoproteincarrier
CapmatinibCytochrome P450 3A4enzyme
CapmatinibAldehyde oxidaseenzyme
CapmatinibHepatocyte growth factor receptortarget
CapmatinibP-glycoprotein 1transporter
CapmatinibMultidrug and toxin extrusion protein 1transporter
CapmatinibMultidrug and toxin extrusion protein 2transporter
CapmatinibCytochrome P450 1A2enzyme
CapmatinibATP-binding cassette sub-family G member 2transporter
BentiromideSerine protease hepsintarget
Salicylic acidSerum albumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidSolute carrier family 22 member 8transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
OlsalazineInterferon gammatarget
OlsalazineThiopurine S-methyltransferasetarget
Magnesium salicylateSerum albumincarrier
Magnesium salicylateProstaglandin G/H synthase 1target
Magnesium salicylateProstaglandin G/H synthase 2target
SalsalateProstaglandin G/H synthase 1target
SalsalateProstaglandin G/H synthase 2target
Choline magnesium trisalicylateProstaglandin G/H synthase 1target
Choline magnesium trisalicylateProstaglandin G/H synthase 2target
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
RoflumilastCytochrome P450 3A4enzyme
Benzene Hexacarboxylic AcidPhosphoglycerate mutase 2target
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
3-(5-amino-7-hydroxy-(1,2,3)triazolo(4,5-d)pyrimidin-2-yl)benzoic acidDihydroneopterin aldolasetarget
GabaculineOrnithine aminotransferase, mitochondrialtarget
GabaculineGlutamate-1-semialdehyde 2,1-aminomutasetarget
4-guanidinobenzoic acidComplement factor Btarget
Pyromellitic AcidFumarate hydratase class IItarget
2,4-Dihydroxybenzoic Acidp-hydroxybenzoate hydroxylasetarget
2,4-Dihydroxybenzoic Acidp-hydroxybenzoate hydroxylasetarget
Arotinoid acidRetinoic acid receptor betatarget
3-MethoxybenzamidePoly [ADP-ribose] polymerase 1target
4-FluorobenzylamineTrypsin-1target
GW-3965Oxysterols receptor LXR-betatarget
CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
BalanolcAMP-dependent protein kinase catalytic subunit alphatarget
1-(4-Amidinophenyl)-3-(4-Chlorophenyl)UreaTrypsin-1target
Renzapride5-hydroxytryptamine receptor 3Atarget
Renzapride5-hydroxytryptamine receptor 4target
ItoprideDopamine D2 receptortarget
ItoprideAcetylcholinesterasetarget
TamibaroteneRetinoic acid receptor alphatarget
TamibaroteneRetinoic acid receptor betatarget
TamibaroteneCellular retinoic acid-binding protein 1carrier
ApadenosonAdenosine receptor A2atarget
ADL5859Delta-type opioid receptortarget
INCB3284C-C chemokine receptor type 2target
Atl146eAdenosine receptor A2atarget
APD7915-hydroxytryptamine receptor 2Atarget
VX-765Caspase-1target
VX-765Interleukin-1 betatarget
Naronapride5-hydroxytryptamine receptor 4target
SLx-4090Microsomal triglyceride transfer protein large subunittarget
SNX-5422Heat shock protein HSP 90-alphatarget
SNX-5422Heat shock protein HSP 90-betatarget
SolabegronBeta-3 adrenergic receptortarget
EltrombopagThrombopoietin receptortarget
EltrombopagCytochrome P450 2C8enzyme
EltrombopagCytochrome P450 1A2enzyme
EltrombopagUDP-glucuronosyltransferase 1-1enzyme
EltrombopagUDP-glucuronosyltransferase 1-3enzyme
EltrombopagSolute carrier organic anion transporter family member 1B1transporter
EltrombopagATP-binding cassette sub-family G member 2transporter
EltrombopagUDP-glucuronosyltransferase 1-9enzyme
AplavirocC-C chemokine receptor type 5target
SaredutantSubstance-K receptortarget
PD-0325901Dual specificity mitogen-activated protein kinase kinase 1target
PH-797804Mitogen-activated protein kinase 14target
Platensimycin3-oxoacyl-[acyl-carrier-protein] synthase 2target
Prephenic acidChorismate mutase AroHtarget
4-(Dimethylamino)benzoic acidReplicase polyprotein 1abtarget
4-(Dimethylamino)benzoic acidOrf1a polyproteintarget
Cinitapride5-hydroxytryptamine receptor 1Atarget
Cinitapride5-hydroxytryptamine receptor 4target
Cinitapride5-hydroxytryptamine receptor 2Atarget
TriflusalProstaglandin G/H synthase 1target
TriflusalNuclear factor NF-kappa-B p105 subunittarget
TriflusalNitric oxide synthase, inducibletarget
TriflusalcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
TriflusalSerum albumincarrier
EnzalutamideSerum albumincarrier
EnzalutamideCytochrome P450 2C8enzyme
EnzalutamideCytochrome P450 3A4enzyme
EnzalutamideAndrogen receptortarget
EnzalutamideCytochrome P450 2C9enzyme
EnzalutamideCytochrome P450 2C19enzyme
EnzalutamideCytochrome P450 2B6enzyme
EnzalutamideCytochrome P450 3A5enzyme
EnzalutamideP-glycoprotein 1transporter
EnzalutamideThyroxine-binding globulincarrier
AmylocaineVoltage-gated sodium channel alpha subunittarget
HomosalateProgesterone receptortarget
HomosalateAndrogen receptortarget
HomosalateEstrogen receptor alphatarget
Phenyl salicylateProstaglandin G/H synthase 1target
Phenyl salicylateProstaglandin G/H synthase 2target
Trolamine salicylateProstaglandin G/H synthase 1target
Trolamine salicylateProstaglandin G/H synthase 2target
ButambenVoltage-dependent calcium channeltarget
ButambenCholinesteraseenzyme
ButambenAlpha-1-acid glycoprotein 1carrier
ButambenSerum albumincarrier
ButambenATP-sensitive potassium channeltarget
ButambenTransient receptor potential cation channel subfamily A member 1target
ButambenTransient receptor potential cation channel subfamily V member 4target
Glycol salicylateProstaglandin G/H synthase 1target
Glycol salicylateProstaglandin G/H synthase 2target
CandoxatrilatNeprilysintarget
MocetinostatHistone deacetylase 1target
MocetinostatHistone deacetylase 3target
MocetinostatHistone deacetylase 2target
EntinostatHistone deacetylasetarget
TecovirimatEnvelope protein F13target
TecovirimatUDP-glucuronosyltransferase 1-1enzyme
TecovirimatUDP-glucuronosyltransferase 1-4enzyme
RadotinibTyrosine-protein kinase ABL1target
BetrixabanP-glycoprotein 1transporter
BetrixabanCoagulation factor Xtarget
BetrixabanPotassium voltage-gated channel subfamily H member 2transporter
RociverineMuscarinic acetylcholine receptor M1target
RociverineMuscarinic acetylcholine receptor M2target
RociverineMuscarinic acetylcholine receptor M3target
RociverineMuscarinic acetylcholine receptor M4target
RociverineMuscarinic acetylcholine receptor M5target
IniparibPoly [ADP-ribose] polymerase 1target
NetarsudilRho-associated protein kinase 1target
NetarsudilRho-associated protein kinase 2target
NetarsudilSodium-dependent noradrenaline transportertarget
Choline salicylateCholine-phosphate cytidylyltransferase Btarget
Choline salicylateAcetylcholinesterasetarget
Choline salicylateCholine-phosphate cytidylyltransferase Atarget
Choline salicylatePhospholipase D2target
Choline salicylateCholinesterasetarget
Choline salicylatePhospholipase D1target
Choline salicylateSolute carrier family 22 member 2transporter
Choline salicylateSolute carrier family 22 member 1transporter
Choline salicylateSolute carrier family 22 member 3transporter
Choline salicylateSolute carrier family 22 member 5transporter
Choline salicylateSolute carrier family 22 member 4transporter
Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
Choline salicylateCholine transporter-like protein 1transporter
Choline salicylateCholine transporter-like protein 4transporter
Choline salicylateCholine transporter-like protein 3transporter
Choline salicylateCholine/ethanolamine kinaseenzyme
Choline salicylateCholine O-acetyltransferaseenzyme
Choline salicylateCholine kinase alphaenzyme
Choline salicylateCholine dehydrogenase, mitochondrialenzyme
Choline salicylateHigh affinity choline transporter 1transporter
Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
TrospiumMuscarinic acetylcholine receptor M1target
TrospiumCytochrome P450 2D6enzyme
TrospiumMuscarinic acetylcholine receptor M3target
Aminosalicylic acidGroup IIE secretory phospholipase A2target
Aminosalicylic acidProstaglandin G/H synthase 2target
Aminosalicylic acidArachidonate 5-lipoxygenasetarget
Aminosalicylic acidInhibitor of nuclear factor kappa-B kinase subunit alphatarget
Aminosalicylic acidMyeloperoxidaseenzyme
Aminohippuric acidSolute carrier family 22 member 2transporter
Aminohippuric acidSolute carrier family 22 member 5transporter
Aminohippuric acidSolute carrier family 22 member 6transporter
Aminohippuric acidSolute carrier family 22 member 8transporter
Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 4transporter
Aminohippuric acidSolute carrier family 22 member 11transporter
Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
Aminohippuric acidMultidrug resistance-associated protein 1transporter
Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
Aminohippuric acidMonocarboxylate transporter 1transporter
Aminohippuric acidSolute carrier family 22 member 7transporter
Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
FenoprofenProstaglandin G/H synthase 1target
FenoprofenProstaglandin G/H synthase 2target
FenoprofenSerum albumincarrier
FenoprofenPeroxisome proliferator-activated receptor alphatarget
FenoprofenPeroxisome proliferator-activated receptor gammatarget
Cisapride5-hydroxytryptamine receptor 4target
Cisapride5-hydroxytryptamine receptor 3Atarget
CisapridePotassium voltage-gated channel subfamily H member 2target
Cisapride5-hydroxytryptamine receptor 2Atarget
CisaprideCytochrome P450 3A4enzyme
CisaprideCytochrome P450 3A5enzyme
CisaprideCytochrome P450 3A7enzyme
CisaprideCytochrome P450 2A6enzyme
CisaprideCytochrome P450 2B6enzyme
CisaprideCytochrome P450 2C19enzyme
CisaprideCytochrome P450 2C8enzyme
CisaprideCytochrome P450 2C9enzyme
CisaprideCytochrome P450 2D6enzyme
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
ClidiniumMuscarinic acetylcholine receptor M1target
BumetanideSolute carrier family 12 member 1target
BumetanideCystic fibrosis transmembrane conductance regulatortarget
BumetanideSolute carrier family 12 member 2target
BumetanideSolute carrier family 12 member 4target
BumetanideSolute carrier family 12 member 5target
BumetanideSodium/bile acid cotransportertransporter
BumetanideSolute carrier family 22 member 6transporter
BumetanideSolute carrier family 22 member 8transporter
BumetanideSolute carrier family 22 member 11transporter
BumetanideSolute carrier family 22 member 7transporter
BumetanideSolute carrier organic anion transporter family member 1A2transporter
BumetanideProstaglandin G/H synthase 2enzyme
OxybuprocaineSodium channel protein type 10 subunit alphatarget
OxybuprocaineCholinesteraseenzyme
Meclofenamic acidProstaglandin G/H synthase 1target
Meclofenamic acidProstaglandin G/H synthase 2target
Meclofenamic acidArachidonate 5-lipoxygenasetarget
Meclofenamic acidSolute carrier family 22 member 6transporter
Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
Meclofenamic acidThyroxine-binding globulincarrier
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenSerum albumincarrier
KetoprofenMultidrug resistance-associated protein 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenSolute carrier family 22 member 8transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1-1enzyme
BalsalazideProstaglandin G/H synthase 1target
BalsalazideProstaglandin G/H synthase 2target
BalsalazideArachidonate 5-lipoxygenasetarget
BalsalazidePeroxisome proliferator-activated receptor gammatarget
BalsalazideNADPH azoreductaseenzyme
ProcainamideSodium channel protein type 5 subunit alphatarget
ProcainamideDNA (cytosine-5)-methyltransferase 1target
ProcainamideCytochrome P450 2D6enzyme
ProcainamideCholinesteraseenzyme
ProcainamideSolute carrier family 22 member 2transporter
ProcainamideSolute carrier family 22 member 1transporter
ProcainamideSolute carrier family 22 member 3transporter
ProcainamideSolute carrier family 22 member 5transporter
ProcainamideSolute carrier family 22 member 4transporter
ProcainamidePotassium voltage-gated channel subfamily H member 2target
ProcainamideMultidrug and toxin extrusion protein 1transporter
ProcainamideMultidrug and toxin extrusion protein 2transporter
ThalidomideCytochrome P450 2C19enzyme
ThalidomideCytochrome P450 2C9enzyme
ThalidomideProstaglandin G/H synthase 1enzyme
ThalidomideProstaglandin G/H synthase 2enzyme
ThalidomideCytochrome P450 3A5enzyme
ThalidomideDNAtarget
ThalidomideProtein cereblontarget
Thalidomidealpha1-acid glycoproteintarget
ThalidomideCytochrome P450 3A4enzyme
ThalidomideCytochrome P450 1A1enzyme
ThalidomideCytochrome P450 2B6enzyme
ChloroprocaineSodium channel protein type 10 subunit alphatarget
ChloroprocaineSodium-dependent dopamine transportertarget
ChloroprocaineCholinesteraseenzyme
ProcarbazineDNAtarget
ProcarbazineXanthine dehydrogenase/oxidaseenzyme
ProcarbazineMonoamine oxidasetarget
MoclobemideAmine oxidase [flavin-containing] Atarget
MoclobemideCytochrome P450 2C19enzyme
MoclobemideCytochrome P450 2D6enzyme
MoclobemideAmine oxidase [flavin-containing] Aenzyme
MoclobemideAmine oxidase [flavin-containing] Benzyme
MoclobemideCytochrome P450 2C9enzyme
MoclobemideMonoamine oxidasetarget
MoclobemideAmine oxidase [flavin-containing] Btarget
LumiracoxibProstaglandin G/H synthase 2target
LumiracoxibProstaglandin G/H synthase 1target
LumiracoxibCytochrome P450 2C9enzyme
LumiracoxibCytochrome P450 2C19enzyme
LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
LumiracoxibCytochrome P450 1A2enzyme
BezafibratePeroxisome proliferator-activated receptor alphatarget
BezafibrateSolute carrier organic anion transporter family member 1B1transporter
BezafibratePeroxisome proliferator-activated receptor deltatarget
BezafibratePeroxisome proliferator-activated receptor gammatarget
BezafibrateCytochrome P450 1A1enzyme
BezafibrateCytochrome P450 2C8enzyme
BezafibrateCytochrome P450 3A4enzyme
BezafibrateNuclear receptor subfamily 1 group I member 2target
BezafibrateRetinoic acid receptor RXR-alphatarget
BezafibrateRetinoic acid receptor RXR-betatarget
BezafibrateRetinoic acid receptor RXR-gammatarget
DeferasiroxIrontarget
DeferasiroxCytochrome P450 3A4enzyme
DeferasiroxUDP-glucuronosyltransferase 1-1enzyme
DeferasiroxUDP-glucuronosyltransferase 1-3enzyme
DeferasiroxUDP-glucuronosyltransferase 1-9enzyme
DeferasiroxCytochrome P450 2C8enzyme
DeferasiroxCytochrome P450 1A2enzyme
p-Hydroxymercuribenzoic acidCarbonic anhydrase 2target
3,4-Dihydroxycinnamic AcidPhotoactive yellow proteintarget
3,4-Dihydroxycinnamic AcidHistidine ammonia-lyasetarget
3,4-Dihydroxycinnamic AcidMacrophage migration inhibitory factortarget
3-phenylpropionic acidAspartate aminotransferasetarget
3-phenylpropionic acidAromatic-amino-acid aminotransferasetarget
3-phenylpropionic acidAminotransferasetarget
Vanillic acidChorismate--pyruvate lyasetarget
O-SuccinylbenzoateN-acylamino acid racemasetarget
O-Succinylbenzoateo-succinylbenzoate synthasetarget
O-SuccinylbenzoateO-succinylbenzoate-CoA synthasetarget
Flufenamic acidAldo-keto reductase family 1 member C3target
Flufenamic acidTransthyretincarrier
Flufenamic acidProstaglandin G/H synthase 2target
Flufenamic acidProstaglandin G/H synthase 1target
Flufenamic acidSolute carrier family 22 member 6transporter
Flufenamic acidAndrogen receptortarget
Flufenamic acidPeroxisome proliferator-activated receptor alphatarget
Flufenamic acidPeroxisome proliferator-activated receptor gammatarget
Benzoylformic AcidHydroxyacid oxidase 1target
Aminobenzoic acidp-hydroxybenzoate hydroxylasetarget
JE-2147Gag-Pol polyproteintarget
Compound 18Estrogen receptor alphatarget
Phthalic AcidNicotinate-nucleotide pyrophosphorylase [carboxylating]target
Phthalic AcidSolute carrier organic anion transporter family member 2B1transporter
Phthalic AcidEstrogen receptor alphatarget
Phthalic AcidProgesterone receptortarget
Phthalic AcidEstrogen receptor betatarget
Phthalic AcidPeroxisome proliferator-activated receptor alphatarget
Phthalic AcidPeroxisome proliferator-activated receptor deltatarget
Phthalic AcidPeroxisome proliferator-activated receptor gammatarget
Phthalic AcidRetinoic acid receptor RXR-alphatarget
Phthalic AcidRetinoic acid receptor RXR-betatarget
Phthalic AcidRetinoic acid receptor RXR-gammatarget
Isochorismic AcidPhenazine biosynthesis protein PhzDtarget
P-Anisic AcidGroup IIE secretory phospholipase A2target
P-Anisic AcidPhospholipase A2target
Mant-AdpMyosin-14target
KB-141Thyroid hormone receptor betatarget
KB-141Thyroid hormone receptor alphatarget
Diphenylacetic acidCathepsin Btarget
3-hydroxyanthranilic acidTrans-2,3-dihydro-3-hydroxyanthranilate isomerasetarget
p-Chlorobenzoic acid4-chlorobenzoyl CoA ligasetarget
Benzoic acidCocaine esterasetarget
Benzoic acidD-amino-acid oxidasetarget
Benzoic acidChlorocatechol 1,2-dioxygenasetarget
Benzoic acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
Benzoic acidNon-heme chloroperoxidasetarget
Benzoic acidOxygen-insensitive NAD(P)H nitroreductasetarget
Benzoic acidHydroxyquinol 1,2-dioxygenasetarget
Benzoic acidReplication proteintarget
Benzoic acidSolute carrier organic anion transporter family member 2B1transporter
Benzoic acidSolute carrier family 22 member 8transporter
Benzoic acidMonocarboxylate transporter 1transporter
Benzoic acidSolute carrier family 15 member 1target
3-Dehydroquinic Acid3-dehydroquinate dehydratasetarget
Phenylpyruvic acidMonocarboxylate transporter 4transporter
Phenylpyruvic acidL-phenylalanine dehydrogenasetarget
Phenylpyruvic acidHydroxyacid oxidase 1target
Phenylpyruvic acidIndole-3-pyruvate decarboxylasetarget
Phenylpyruvic acidPutative uncharacterized proteintarget
Phenylpyruvic acidBacilysin biosynthesis protein BacBtarget
Phenylpyruvic acidProbable chorismate mutasetarget
Phloretic acidTyrosine phenol-lyasetarget
Phloretic acidTyrosine phenol-lyasetarget
Phloretic acidPrephenate dehydrogenasetarget
p-Coumaric acidPhotoactive yellow proteintarget
p-Coumaric acidPPHtarget
p-Coumaric acidProstaglandin reductase 1target
p-Coumaric acidHistidine ammonia-lyasetarget
Anthranilic acidL-amino-acid oxidasetarget
Anthranilic acidD-amino-acid oxidasetarget
4-hydroxybenzoic acidp-hydroxybenzoate hydroxylasetarget
4-hydroxybenzoic acidChorismate--pyruvate lyasetarget
4-hydroxybenzoic acidp-hydroxybenzoate hydroxylasetarget
4-hydroxybenzoic acid4-hydroxybenzoyl-CoA thioesterasetarget
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
Niflumic acidPhospholipase A2target
Niflumic acidChloride channel protein ClC-Katarget
Niflumic acidMonocarboxylate transporter 2transporter
Niflumic acidMonocarboxylate transporter 1transporter
Niflumic acidProstaglandin G/H synthase 2target
Niflumic acidProstaglandin G/H synthase 1target
Niflumic acidCytosolic phospholipase A2target
Niflumic acidUDP-glucuronosyltransferase 1-9target
Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
IodipamideSerum albumincarrier
CyclandelateVoltage-dependent calcium channel subunit alpha-2/delta-1target
CyclandelateLiver carboxylesterase 1target
CyclandelateCytochrome P450 3A4enzyme
MepenzolateMuscarinic acetylcholine receptor M1target
MepenzolateMuscarinic acetylcholine receptor M3target
DarusentanEndothelin-1 receptortarget
RonacaleretExtracellular calcium-sensing receptortarget
OMS-103HPTumor necrosis factortarget
OMS-103HPInterleukin-1 receptor type 1target
PX-478Hypoxia-inducible factor 1-alphatarget
AmbrisentanEndothelin B receptortarget
AmbrisentanEndothelin-1 receptortarget
AmbrisentanCytochrome P450 2C19enzyme
AmbrisentanCytochrome P450 3A4enzyme
AmbrisentanUDP-glucuronosyltransferase 1-9enzyme
AmbrisentanUDP-glucuronosyltransferase 1-3enzyme
AmbrisentanUDP-glucuronosyltransferase 2B7enzyme
AmbrisentanP-glycoprotein 1transporter
AmbrisentanSolute carrier organic anion transporter family member 1B1transporter
AmbrisentanSolute carrier organic anion transporter family member 1B3transporter
AmbrisentanCytochrome P450 3A5enzyme
DeclopramideDNAtarget
DeclopramideDNA topoisomerase 2-alphatarget
DeclopramideDNA topoisomerase 2-betatarget
Ticalopride5-hydroxytryptamine receptor 4target
Ticalopride5-hydroxytryptamine receptor 3Atarget
ErtiprotafibTyrosine-protein phosphatase non-receptor type 1target
ErtiprotafibInhibitor of nuclear factor kappa-B kinase subunit betatarget
ErtiprotafibPeroxisome proliferator-activated receptor alphatarget
ErtiprotafibPeroxisome proliferator-activated receptor gammatarget
RagaglitazarPeroxisome proliferator-activated receptor alphatarget
RagaglitazarPeroxisome proliferator-activated receptor gammatarget
TesaglitazarPeroxisome proliferator-activated receptor alphatarget
TesaglitazarPeroxisome proliferator-activated receptor gammatarget
AxitinibVascular endothelial growth factor receptor 1target
AxitinibVascular endothelial growth factor receptor 2target
AxitinibVascular endothelial growth factor receptor 3target
AxitinibCytochrome P450 3A4enzyme
AxitinibCytochrome P450 3A5enzyme
AxitinibCytochrome P450 1A2enzyme
AxitinibCytochrome P450 2C19enzyme
AxitinibUDP-glucuronosyltransferase 1-1enzyme
AxitinibP-glycoprotein 1transporter
AxitinibSolute carrier organic anion transporter family member 1B1transporter
AceclofenacCytochrome P450 2C9enzyme
AceclofenacProstaglandin G/H synthase 2target
AceclofenacProstaglandin G/H synthase 1target
Phenylbutyric acidAromatic-amino-acid aminotransferasetarget
Phenylbutyric acidThermolysintarget
Phenylbutyric acidCytochrome P450 2D6enzyme
Phenylbutyric acidHistone deacetylasetarget
m-Hydroxyhippuric acidKynureninasetarget
Isoferulic acidO-methyltransferasetarget
p-Nitrophenylacetic acidPenicillin G acylasetarget
AcifluorfenProtoporphyrinogen oxidasetarget
AcifluorfenProtoporphyrinogen oxidasetarget
FelbinacCathepsin L1target
TranilastHematopoietic prostaglandin D synthasetarget
TranilastCytochrome P450 3A4enzyme
TranilastCytochrome P450 2C9enzyme
alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acidChymotrypsinogen Btarget
4-Hydroxyphenylpyruvic acidProthrombintarget
4-Hydroxyphenylpyruvic acidMacrophage migration inhibitory factortarget
4-Hydroxyphenylpyruvic acidPrephenate dehydrogenasetarget
Ferulic acidEndo-1,4-beta-xylanase Ytarget
Ferulic acidEndo-1,4-beta-xylanase Ztarget
Ferulic acidEst1etarget
Ferulic acidO-methyltransferasetarget
Ferulic acidMonocarboxylate transporter 1transporter
Ferulic acidMonocarboxylate transporter 4transporter
Homogentisic acidPenicillin G acylasetarget
Puromycin60S ribosomal protein L10-liketarget
Puromycin60S ribosomal protein L13atarget
Puromycin60S ribosomal protein L23target
Puromycin60S ribosomal protein L15target
Puromycin60S ribosomal protein L19target
Puromycin60S ribosomal protein L23atarget
PuromycinProbable ribosome biogenesis protein RLP24target
Puromycin60S ribosomal protein L26-like 1target
Puromycin60S ribosomal protein L8target
Puromycin60S ribosomal protein L37target
Puromycin60S ribosomal protein L3target
Puromycin60S ribosomal protein L11target
PuromycinLeucyl/phenylalanyl-tRNA--protein transferasetarget
4-(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACIDNeuraminidasetarget
4-(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACIDNeuraminidasetarget
Sinapic acidEndo-1,4-beta-xylanase Ytarget
2-Hydroxybenzalpyruvate2-hydroxychromene-2-carboxylate isomerasetarget
Methyl vanillateEndo-1,4-beta-xylanase Ytarget
N-CaffeoyltyraminePeptide deformylasetarget
Glycerol phenylbutyratePancreatic triacylglycerol lipaseenzyme
Glycerol phenylbutyrateCytochrome P450 3A4enzyme
Glycerol phenylbutyrateCytochrome P450 2D6enzyme
PomalidomideCytochrome P450 1A2enzyme
PomalidomideCytochrome P450 3A4enzyme
PomalidomideP-glycoprotein 1transporter
PomalidomideProtein cereblontarget
PomalidomideTumor necrosis factortarget
PomalidomideProstaglandin G/H synthase 2target
IndoraminAlpha-1A adrenergic receptortarget
IndoprofenPyruvate kinase PKMtarget
EtofenamateThyroxine-binding globulincarrier
BromoprideDopamine D2 receptortarget
TetracaineRyanodine receptor 1target
TetracaineRyanodine receptor 2target
TetracaineVoltage-gated sodium channel alpha subunittarget
EugenolEstrogen receptor alphatarget
EugenolEstrogen receptor betatarget
EugenolAndrogen receptortarget
EugenolTransient receptor potential cation channel subfamily V member 3target
TrimebutineMu-type opioid receptortarget
TrimebutineVoltage-dependent L-type calcium channeltarget
TrimebutineCalcium-activated potassium channeltarget
TrimebutineVoltage-dependent T-type calcium channeltarget
TrimebutineMuscarinic acetylcholine receptor M1target
TrimebutineMuscarinic acetylcholine receptor M2target
TrimebutineMuscarinic acetylcholine receptor M3target
TrimebutineMuscarinic acetylcholine receptor M4target
TrimebutineCytochrome P450 3A4enzyme
LoxoprofenProstaglandin G/H synthase 2target
LoxoprofenProstaglandin G/H synthase 1target
LoxoprofenCarbonyl reductase [NADPH] 1enzyme
LoxoprofenCytochrome P450 3A Subfamilyenzyme
LoxoprofenUDP-glucuronosyltransferase 2B7enzyme
DexibuprofenProstaglandin G/H synthase 1target
DexibuprofenProstaglandin G/H synthase 2target
DexibuprofenApoptosis regulator Bcl-2target
DexibuprofenThrombomodulintarget
DexibuprofenTissue-type plasminogen activatortarget
DexibuprofenFatty acid-binding protein, intestinaltarget
DexibuprofenPeroxisome proliferator-activated receptor gammatarget
DexibuprofenCystic fibrosis transmembrane conductance regulatortarget
DexibuprofenCytochrome P450 2C9enzyme
DexibuprofenSerum albumincarrier
DexibuprofenMultidrug resistance-associated protein 4transporter
DexibuprofenMultidrug resistance-associated protein 1transporter
DexibuprofenSolute carrier organic anion transporter family member 1A2transporter
DexibuprofenSolute carrier family 22 member 6transporter
DexibuprofenSolute carrier family 22 member 8transporter
DexibuprofenSolute carrier family 22 member 11transporter
DexibuprofenSolute carrier organic anion transporter family member 2B1transporter
DexibuprofenP-glycoprotein 1transporter
DexibuprofenUDP-glucuronosyltransferase 1-1enzyme
DexibuprofenUDP-glucuronosyltransferase 1-3enzyme
DexibuprofenUDP-glucuronosyltransferase 1-9enzyme
DexibuprofenUDP-glucuronosyltransferase 2B4enzyme
DexibuprofenUDP-glucuronosyltransferase 2B7enzyme
DexibuprofenCytochrome P450 2C8enzyme
DexibuprofenCytochrome P450 2C19enzyme
DexibuprofenSolute carrier family 15 member 1target
DexibuprofenPeroxisome proliferator-activated receptor alphatarget
DexibuprofenPlatelet glycoprotein Ib alpha chaintarget
DexibuprofenProtein S100-A7target
DexibuprofenAlpha-methylacyl-CoA racemaseenzyme
DexketoprofenProstaglandin G/H synthase 1target
DexketoprofenProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1enzyme
DexketoprofenProstaglandin G/H synthase 2enzyme
Tolfenamic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 2target
Tolfenamic acidCytochrome P450 3A4enzyme
Phenylacetic acidLiver carboxylesterase 1enzyme
MorniflumateArachidonate 5-lipoxygenasetarget
MorniflumateProstaglandin G/H synthase 2target
MorniflumateArachidonate 5-lipoxygenaseenzyme
MorniflumateProstaglandin G/H synthase 2enzyme
MorniflumateLeukotriene B4 receptor 1target
MorniflumateThromboxane A2 receptortarget
MorniflumateUDP-glucuronosyltransferase 1-9enzyme
PropoxycaineLiver carboxylesterase 1enzyme
PropoxycaineVoltage-gated sodium channel alpha subunittarget
Acetrizoic acidSerum albumincarrier
NonivamideTransient receptor potential cation channel subfamily V member 1target
RobenacoxibCyclooxygenase 2target
ArhalofenatePeroxisome proliferator-activated receptor gammatarget
PropiverineMuscarinic acetylcholine receptor M1target
PropiverineMuscarinic acetylcholine receptor M2target
PropiverineMuscarinic acetylcholine receptor M3target
PropiverineMuscarinic acetylcholine receptor M4target
PropiverineMuscarinic acetylcholine receptor M5target
PropiverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
PropiverineAlpha-1A adrenergic receptortarget
PropiverineCytochrome P450 3A4enzyme
PropiverineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
PropiverineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
Propyl GallateEstrogen receptor alphatarget
RacloprideDopamine D2 receptortarget
NaveglitazarPeroxisome proliferator-activated receptor gammatarget
TiaprideDopamine D2 receptortarget
TiaprideDopamine D3 receptortarget
TiaprideSerotonin Receptorstarget
TiaprideAlpha-1 adrenergic receptorstarget
TiaprideAlpha-2 adrenergic receptorstarget
LusutrombopagCytochrome P450 4A11enzyme
LusutrombopagP-glycoprotein 1transporter
LusutrombopagATP-binding cassette sub-family G member 2transporter
LusutrombopagThrombopoietin receptortarget
AlclofenacProstaglandin G/H synthase 2target
Bismuth subgallateSerum albumincarrier
VicagrelLiver carboxylesterase 1enzyme
VicagrelIntestinal-type alkaline phosphataseenzyme
VicagrelCytochrome P450 2C19enzyme
VicagrelCocaine esteraseenzyme
VicagrelP2Y purinoceptor 12target
VicagrelArylacetamide deacetylaseenzyme