Abequolixron

DB17146InvestigationalSmall molecule

Abequolixron: Overview.

Mechanism: Pharmacologically active on Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha
Curator reviewed
Formula / weight: C₃₄H₃₃ClF₃NO₃ · 596.09 g/mol (avg)
Also known as: 2-{3-[(3R)-3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)butoxy]phenyl}acetic acid
Code names: RGX-104 · SB-742881

Resolves to

Compound

Structure

InChIKeyZLJZDYOBXVOTSA-XMMPIXPASA-NSMILESC[C@H](CCOC1=CC(CC(O)=O)=CC=C1)N(CC(C1=CC=CC=C1)C1=CC=CC=C1)CC1=C(Cl)C(=CC=C1)C(F)(F)F

Targets

What you can answer from here — as of July 08, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

15+ReferencesStructured and connected to the statements they support

Which drugs share a target with Abequolixron, and which of those have an active Phase 3 trial?

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