Dopamine Agonists
- Name
- Dopamine Agonists
- Accession Number
- DBCAT000607
- Description
Drugs that bind to and activate dopamine receptors.
- ATC Classification
- Drugs
Drug Drug Description Ropinirole A non-ergoline dopamine agonist used to treat the symptoms of Parkinson's disease and Restless Legs Syndrome. Pramipexole A non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS). Apomorphine A morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease. Pergolide A long-acting dopamine agonist that is uncommonly used for the management of Parkinson's disease, due to the risk for cardiac valvulopathy. Bromocriptine A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. Rotigotine A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome. Piribedil A dopamine agonist used with or without levodopa in the treatment of Parkinson's disease. Dihydroergocryptine A dopamine agonist indicated in the treatment of cerebrovascular diseases and atherosclerosis. Fenoldopam A dopamine D1 receptor agonist used for the short term management of hypertension. Cabergoline A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes. Dihydroergotamine An ergot alkaloid used in the acute treatment of migraine headache and cluster headache. Ergoloid mesylate A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. Dihydroergocornine A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. Dopexamine Dopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer. Dihydrexidine Dihydrexidine has been used in trials studying the treatment of SPD, Cocaine-Related Disorders, and Schizotypal Personality Disorder. Ibopamine A sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia. Metergoline An ergot-derivative that acts as an antagonist at certain 5-HT receptor subtypes and as an agonist at dopamine receptors. It is often used in situations where inhibition of prolactin is desirable. Lisuride For the management of Parkinson's Disease Quinagolide A dopamine D2 receptor agonist used for the treatment of hyperprolactinemia. Brexpiprazole A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct, schizophrenia, and agitation associated with dementia due to Alzheimer’s disease. Aripiprazole An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. Dexpramipexole Dexpramipexole is under investigation in clinical trial NCT01511029 (Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of... Lumateperone A novel 2nd generation antipsychotic used to manage both positive and negative symptoms in patients with schizophrenia. DAR-0100A DAR-0100A is under investigation in clinical trial NCT01466205 (Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder). Dihydroergotoxine Not Annotated Epicriptine A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. Cariprazine An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder. GBR-12783 A selective inhibitor of dopamine uptake. - Drugs & Drug Targets