Pesticides

Name
Pesticides
Accession Number
DBCAT000639
Description

Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.

Drugs
DrugDrug Description
CrotamitonA topical scabicidal and antipruritic agent used for scabies eradication and for the relief of pruritus.
LindaneAn ectoparasiticide and ovicide used in the treatment of Pediculosis humanis capitis (head lice) and Phthirus pubis (crab lice).
IvermectinAn anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
Benzyl benzoateA topical treatment for scabies and lice.
WarfarinA vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.
MalathionA parasympathomimetic organophosphate used to treat head lice.
Malachite GreenNot Available
GlyphosateNot Available
AllosamidinAllosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
CarboxinA systemic agricultural fungicide and seed treatment agent.
PermethrinAn insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
NiclosamideAn anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.
SpinosadA pediculicide used topically to treat head lice.
Piperonyl butoxideA pesticide used as a potentiator ingredient in the treatment of pediculosis (head lice, body lice or crabs) to boost efficacy of treatment.
Pyrethrum extractA chrysanthemum flower extract used to treat head, pubic, and body lice.
DiethyltoluamideAn insect repellant, also known as DEET.
Boric acidNo FDA- or EMA-approved therapeutic indications on its own.
AmitrazAmitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as...
CoumaphosThis drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a...
CythioateCythioate is a member of the organothiophosphate compounds that is used as an insecticide and anthelmintic. It is mainly used in veterinary as a treatment for fleas.
DichlorvosDichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products...
DoramectinDoramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in...
EprinomectinNot Annotated
FamphurNot Annotated
FenthionFenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is...
ImidaclopridImidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and...
LufenuronLufenuron is used in veterinary for the control of flea.
MoxidectinMoxidectin is indicated for the treatment of river blindness, also called onchocerciasis, in patients aged 12 years and older. River blindness is caused by a parasitic worm Onchocerca volvulus and...
PhosmetPhosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals,...
RotenoneRotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also...
MetrifonateMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
TemefosDiphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.
NeosaxitoxinNeosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local Anesthetic).
CarbendazimCarbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
ThiramThiram may be used in dermatology as a scabicide . Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for...
DimethylphthalateNot Annotated
ParaoxonNot Annotated
DeltamethrinNot Annotated
PhenothrinA pyrethroid indicated in the treatment of head lice.
CypermethrinA medication used to treat parasitic skin diseases.
BioallethrinBioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
TetramethrinNot Annotated
CyfluthrinNot Annotated
1,2-dichlorobenzene1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound...
Chloric acidNot Annotated
AcifluorfenAcifluorfen is a protoporphyrinogen oxidase inhibitor.
Cacodylic acidNot Available
DiethyltryptamineDiethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.
MethamidophosMethamidophos is under investigation in clinical trial NCT03223753 (Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia in First Remission).
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
ImazaquinNot Available
Fenoxaprop-ethylChronic angina and Coronary Artery Disease
NitenpyramNitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly...
FenpropidinFenpropidin has been investigated for the treatment of Hernia.
TransfluthrinTransfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).
TerbutrynNot Available
AtrazineAtrazine is a selective triazine herbicide. Inhalation hazard is low and there are no apparent skin manifestations or other toxicity in humans. Acutely poisoned sheep and cattle may show muscular...
ThiaclopridNot Available
CarbarylA medication used in shampoo to remove lice.
Drugs & Drug Targets
DrugTargetType
LindaneGamma-aminobutyric acid receptor subunit beta-1target
LindaneGlycine receptor subunit alpha-1target
LindaneGlycine receptor subunit alpha-2target
LindaneGlycine receptor subunit alpha-3target
LindaneGlycine receptor subunit betatarget
LindaneGamma-aminobutyric acid receptor subunit beta-3target
LindaneGamma-aminobutyric acid receptor subunit rho-1target
LindaneProgesterone receptortarget
LindaneEstrogen receptor alphatarget
LindaneNuclear receptor subfamily 1 group I member 2target
IvermectinP-glycoprotein 1transporter
IvermectinMultidrug resistance-associated protein 1transporter
IvermectinCanalicular multispecific organic anion transporter 1transporter
IvermectinATP-binding cassette sub-family G member 2transporter
IvermectinCytochrome P450 3A4enzyme
IvermectinSolute carrier organic anion transporter family member 1B1transporter
IvermectinSolute carrier organic anion transporter family member 1B3transporter
IvermectinCytochrome P450 2D6enzyme
IvermectinCytochrome P450 2E1enzyme
WarfarinVitamin K epoxide reductase complex subunit 1target
WarfarinCytochrome P450 2C8enzyme
WarfarinCytochrome P450 1A2enzyme
WarfarinCytochrome P450 2C9enzyme
WarfarinAlpha-1-acid glycoprotein 1carrier
WarfarinSerum albumincarrier
WarfarinCytochrome P450 2C19enzyme
WarfarinCytochrome P450 3A4enzyme
WarfarinCytochrome P450 2C18enzyme
WarfarinNuclear receptor subfamily 1 group I member 2target
MalathionCholinesterasetarget
MalathionCytochrome P450 1A2enzyme
MalathionCytochrome P450 2B6enzyme
Malachite GreenHTH-type transcriptional regulator QacRtarget
Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
GlyphosateCytochrome P450 19A1target
GlyphosateSerum albumincarrier
AllosamidinChitinase Btarget
AllosamidinChitinase Atarget
CarboxinSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
PermethrinCytochrome P450 2B6enzyme
PermethrinSodium channel protein type 1 subunit alphatarget
PermethrinEstrogen receptor alphatarget
PermethrinNuclear receptor subfamily 1 group I member 2target
NiclosamideDNAtarget
NiclosamideCytochrome P450 2C9enzyme
NiclosamideCytochrome P450 1A2enzyme
Pyrethrum extractNuclear receptor subfamily 1 group I member 2target
DichlorvosSerum albumincarrier
DichlorvosSerotransferrintarget
DichlorvosCholinesterasetarget
DoramectinCytochrome P450 3A4enzyme
EprinomectinCytochrome P450 3A4enzyme
ImidaclopridCHRNA7-FAM7A fusion proteintarget
MoxidectinCYP2B proteinenzyme
MoxidectinGlutamate-gated chloride channeltarget
MoxidectinGABA-A gated chloride channeltarget
MoxidectinABC transporterstarget
BioallethrinVoltage-gated sodium channel alpha subunittarget
BioallethrinSodium channel proteintarget
BioallethrinVoltage-dependent calcium channeltarget
BioallethrinVoltage-dependent T-type calcium channeltarget
BioallethrinVoltage-dependent P/Q-type calcium channeltarget
BioallethrinVoltage-dependent L-type calcium channeltarget
BioallethrinCytochrome P450 2C8enzyme
BioallethrinCytochrome P450 2C9enzyme
BioallethrinCytochrome P450 2C19enzyme
BioallethrinCytochrome P450 3A4enzyme
BioallethrinCytochrome P450 2A1enzyme
BioallethrinCytochrome P450 1A1enzyme
BioallethrinCytochrome P450 2C6enzyme
BioallethrinCytochrome P450 2C11enzyme
BioallethrinCytochrome P450 3A1enzyme
BioallethrinCytochrome P450 3A2enzyme
1,2-dichlorobenzeneCytochrome P450 2E1enzyme
AcifluorfenProtoporphyrinogen oxidasetarget
AcifluorfenProtoporphyrinogen oxidasetarget
Cacodylic acidGag-Pol polyproteintarget
Cacodylic acidNitric oxide synthase, endothelialtarget
Cacodylic acidAldose reductasetarget
Cacodylic acidGuanine nucleotide-binding protein G(t) subunit alpha-1target
Fenoxaprop-ethylNitric oxide synthase, inducibletarget
TerbutrynPhotosynthetic reaction center cytochrome c subunittarget
TerbutrynReaction center protein H chaintarget
TerbutrynReaction center protein L chaintarget
TerbutrynReaction center protein M chaintarget
TerbutrynReaction center protein L chaintarget
TerbutrynReaction center protein M chaintarget
TerbutrynReaction center protein H chaintarget
AtrazinePhotosynthetic reaction center cytochrome c subunittarget
AtrazineReaction center protein H chaintarget
AtrazineReaction center protein L chaintarget
AtrazineReaction center protein M chaintarget
ThiaclopridCHRNA7-FAM7A fusion proteintarget