Coumaphos

DB11390ExperimentalVet approvedSmall molecule

This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a... Coumaphos is widely used for both farm and domestic animals to control ticks, mites, flies and fleas.

Mechanism: Pharmacologically active on Acetylcholinesterase
Curator reviewed
Formula / weight: C₁₄H₁₆ClO₅PS · 362.766 g/mol (avg)
Also known as: Coumafos
Code names: BAYER-21199

Resolves to

Compound

UNIIL08SZ5Z5JCCAS56-72-4ChEMBLCHEMBL251680ChEBI3903KEGGD07750

Clinical / RWD

RxNorm2745582

Structure

InChIKeyBXNANOICGRISHX-UHFFFAOYSA-NSMILESCCOP(=S)(OCC)OC1=CC2=C(C=C1)C(C)=C(Cl)C(=O)O2

Targets

P22303ACHE

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

637Drug interactionsStructured to mechanism, not free text

13+ReferencesStructured and connected to the statements they support

Which drugs share a target with Coumaphos, and which of those have an active Phase 3 trial?

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