Calcium Chelating Agents

Accession Number

DBCAT001213

Description

Substances that bind to and sequester CALCIUM ions.

Drugs

Drug	Drug Description
Edetic acid	A chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias.
Citric acid	An anti-chelation additive used in blood collection tubes and as a flavoring and preservative agent in various cosmetic and pharmaceutical products.
Edetate disodium anhydrous	A polyvalent ion chelator indicated for emergency treatment of hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Edetate calcium disodium anhydrous	A chelating agent used to treat lead poisoning.

Drugs & Drug Targets

Drug	Target	Type
Edetic acid	Lead	target
Edetic acid	Iron	target
Edetic acid	Manganese cation	target
Edetic acid	Adenosine deaminase	enzyme
Edetic acid	Serum paraoxonase/lactonase 3	enzyme
Edetic acid	Aromatase	enzyme
Citric acid	Beta-lactamase 2	target
Citric acid	Aldo-keto reductase family 1 member B1	target
Citric acid	Citrate synthase, mitochondrial	target
Citric acid	Proto-oncogene tyrosine-protein kinase Src	target
Citric acid	Ribonuclease pancreatic	target
Citric acid	Isocitrate dehydrogenase [NADP]	target
Citric acid	Eosinophil cationic protein	target
Citric acid	Beta-lactamase	target
Citric acid	Fumarate hydratase class II	target
Citric acid	6-phosphogluconolactonase	target
Citric acid	L-amino-acid oxidase	target
Citric acid	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	target
Citric acid	Cytochrome c peroxidase	target
Citric acid	Hepatocyte growth factor-regulated tyrosine kinase substrate	target
Citric acid	Invasin	target
Citric acid	Intron-associated endonuclease 1	target
Citric acid	Short tail fiber protein gp12	target
Citric acid	Malate dehydrogenase, mitochondrial	target
Citric acid	N5-carboxyaminoimidazole ribonucleotide mutase	target
Citric acid	50S ribosomal protein L4	target
Citric acid	Carboxypeptidase B	target
Citric acid	Hexon protein	target
Citric acid	Riboflavin biosynthesis protein	target
Citric acid	Beta-fructosidase	target
Citric acid	Putative stringent starvation protein A	target
Citric acid	Citrate synthase	target
Citric acid	RNA 3'-terminal phosphate cyclase	target
Citric acid	U6 snRNA-associated Sm-like protein LSm6	target
Citric acid	Pleckstrin homology domain-containing family A member 1	target
Citric acid	Fe(3+)-binding periplasmic protein	target
Citric acid	Signal recognition particle receptor FtsY	target
Citric acid	Nicotinate-nucleotide adenylyltransferase	target
Citric acid	N utilization substance protein B homolog	target
Citric acid	Complement component C8 gamma chain	target
Citric acid	Ribonucleoside-diphosphate reductase subunit beta	target
Citric acid	Glutamine synthetase 1	target
Citric acid	2-methylcitrate synthase	target
Citric acid	Prostaglandin F synthase	target
Citric acid	Adenine phosphoribosyltransferase	target
Citric acid	Glucose-1-phosphate thymidylyltransferase	target
Citric acid	Glyoxalase family protein	target
Citric acid	Laccase domain protein YfiH	target
Citric acid	Ribose-5-phosphate isomerase A	target
Citric acid	GMP synthase [glutamine-hydrolyzing]	target
Citric acid	Inosine triphosphate pyrophosphatase	target
Citric acid	Lysozyme	target
Citric acid	Glycerol uptake operon antiterminator regulatory protein	target
Citric acid	3-carboxy-cis,cis-muconate cycloisomerase	target
Citric acid	Pyruvate decarboxylase	target
Citric acid	Solute carrier organic anion transporter family member 2B1	transporter
Citric acid	Metallo-beta-lactamase type 2	target
Citric acid	Transient receptor potential cation channel subfamily V member 4	target
Citric acid	Lanosterol 14-alpha demethylase	target
Edetate disodium anhydrous	Lead	target
Edetate disodium anhydrous	Iron	target
Edetate disodium anhydrous	Manganese cation	target
Edetate disodium anhydrous	Adenosine deaminase	enzyme
Edetate disodium anhydrous	Serum paraoxonase/lactonase 3	enzyme
Edetate disodium anhydrous	Aromatase	enzyme
Edetate disodium anhydrous	Cytochrome P450 3A4	enzyme
Edetate disodium anhydrous	Serum paraoxonase/arylesterase 1	enzyme
Edetate calcium disodium anhydrous	Manganese cation	target
Edetate calcium disodium anhydrous	Iron	target
Edetate calcium disodium anhydrous	Lead	target
Edetate calcium disodium anhydrous	Adenosine deaminase	enzyme
Edetate calcium disodium anhydrous	Serum paraoxonase/lactonase 3	enzyme
Edetate calcium disodium anhydrous	Aromatase	enzyme
Edetate calcium disodium anhydrous	Cytochrome P450 3A4	enzyme
Edetate calcium disodium anhydrous	Serum paraoxonase/arylesterase 1	enzyme