Pharmaceutical Vehicles

Name
Pharmaceutical Vehicles
Accession Number
DBCAT001429
Description

A carrier or inert medium used as a solvent (or diluent) in which the medicinally active agent is formulated and or administered. (Dictionary of Pharmacy, 1986)

Drugs
DrugDrug Description
2-Hydroxylpropyl-beta-cyclodextrinAdrabetadex is under investigation in clinical trial NCT03887533 (Combined Intrathecal and Intravenous VTS-270 Therapy for Liver and Neurological Disease Associated With Niemann-Pick Disease, Type C1).
BetadexNot Available
Hard fatNot Annotated
Microcrystalline celluloseA polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material,...
Octylphenoxy polyethoxyethanolNot Available
Poloxamer 188A medication used to clean wounds.
Poloxamer 407Poloxamer 407 is a polyoxyethylene polymer and hydrophilic non-ionic surfactant. It consists of a central hydrophobic block of polypropylene glycol that is flanked on each side by polyethylene glycol blocks,...
Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
Polysorbate 20Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is...
Polysorbate 80It is used as a solubilizer, antimicrobial preservative and disinfectant .
Propylene glycolA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Sulfobutylether-beta-cyclodextrinNot Annotated
TragacanthAn extract from Tragacanth used in allergy testing.
TricaprylinTricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease.
TriethylhexanoinTriethylhexanoin is an ingredient of cosmetic products as a fragrant solvent.
TromethamineA proton acceptor used for the prevention and correction of metabolic acidosis associated with various clinical conditions, such as cardiac bypass surgery.
Drugs & Drug Targets
DrugTargetType
2-Hydroxylpropyl-beta-cyclodextrinInsulintarget
2-Hydroxylpropyl-beta-cyclodextrinTranscription factor EBtarget
BetadexMaltogenic amylasetarget
BetadexMaltose/maltodextrin-binding periplasmic proteintarget
BetadexNeopullulanase 2target
Microcrystalline cellulosePancreatic alpha-amylasetarget
Microcrystalline celluloseCellulose 1,4-beta-cellobiosidase (reducing end) CelSenzyme
Microcrystalline celluloseEndoglucanaseenzyme
Microcrystalline cellulosecellulaseenzyme
Octylphenoxy polyethoxyethanolTroponin C, skeletal muscletarget
Poloxamer 188Albumincarrier
Poloxamer 188Fibrinogentarget
Poloxamer 188Cytochrome c oxidase subunit 8A, mitochondrialtarget
Poloxamer 188NADH-ubiquinone oxidoreductase chain 1target
Poloxamer 188Multidrug resistance-associated protein 1transporter
Poloxamer 188Cytochrome P450 3A Subfamilyenzyme
Poloxamer 188Cytochrome P450 3A4enzyme
Poloxamer 188ATP-dependent translocase ABCB1transporter
Poloxamer 407Lipoprotein lipasetarget
Poloxamer 407Pancreatic triacylglycerol lipasetarget
Poloxamer 407ATP-dependent translocase ABCB1transporter
Poloxamer 407Plasminogentarget
Polyethylene glycolATP-dependent translocase ABCB1transporter
Polysorbate 20Interferon alpha-2target
Polysorbate 20Lipoprotein lipaseenzyme
Polysorbate 20Sialate O-acetylesteraseenzyme
Polysorbate 20ATP-dependent translocase ABCB1transporter
Polysorbate 80Multidrug resistance-associated protein 1target
Polysorbate 80ATP-dependent translocase ABCB1target
Polysorbate 80Human Carboxylesterasesenzyme
Polysorbate 80Cytosolic phospholipase A2enzyme
Polysorbate 80Lysosomal acid lipase/cholesteryl ester hydrolaseenzyme
Polysorbate 80Cytochrome P450 3A Subfamilyenzyme
Polysorbate 80Cytochrome P450 3A4enzyme
Polysorbate 80Multidrug resistance-associated protein 1transporter
Polysorbate 80ATP-dependent translocase ABCB1transporter
Propylene glycolGlycerol dehydratasetarget
TromethamineS-adenosylmethionine decarboxylase proenzymetarget
TromethamineAmyloid-beta precursor proteintarget