Sapogenins

Name
Sapogenins
Accession Number
DBCAT001708
Description

The aglucon moiety of a saponin molecule. It may be triterpenoid or steroid, usually spirostan, in nature.

Drugs
DrugDrug Description
SmilageninInvestigated for use/treatment in alzheimer's disease, parkinson's disease and other neurodegenerative diseases.
Bardoxolone methylInvestigated for use/treatment in lymphoma (unspecified), multiple myeloma, and solid tumors.
RuscogeninAn anti-inflammatory steroid used in combination with local anesthetics for the treatment of hemorrhoids and for local anesthesia.
BardoxoloneBardoxolone has been used in trials studying the treatment of LYMPHOMA and Solid Tumors. It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce...
Ursolic acidNot Annotated
Drugs & Drug Targets
DrugTargetType
Bardoxolone methylNF-kappa-B inhibitor alphatarget
BardoxoloneCaspase-8target
Ursolic acidGTPase HRastarget
Ursolic acidNeutrophil elastasetarget