Cysteine Endopeptidases
- Name
- Cysteine Endopeptidases
- Accession Number
- DBCAT001855
- Description
ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.
- Drugs
Drug Drug Description Chymopapain Chymopapain is indicated for the development of chemonucleolysis which is used for the digestion of the nucleus pulposus in patients with disc herniation confirmed by myelography. A disc herniation occurs... Papain A proteolytic enzyme derived from papaya used for its anti-inflammatory properties. Bromelains A protease indicated in the treatment of inflammation and for eschar removal. Stem bromelain The primary medical purpose for which stem bromelain (SB) is currently indicated for is the removal of eschar in adults with deep partial- and full-thickness thermal burns [FDA Label]. Besides... Anacaulase A mix of proteolytic enzymes indicated for eschar removal in adults with deep partial thickness and/or full-thickness thermal burns. - Drugs & Drug Targets
Drug Target Type Chymopapain Bone marrow proteoglycan target Papain Toll-like receptor 4 target Anacaulase Cytochrome P450 2C8 enzyme Anacaulase Cytochrome P450 2C9 enzyme Anacaulase Alpha-1-antichymotrypsin target Anacaulase Alpha-2-macroglobulin target