Amino Acids and Derivatives

Name
Amino Acids and Derivatives
Accession Number
DBCAT002151
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
AdemetionineS-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as...
L-GlutamineAn amino acid commonly found as a component in total parenteral nutrition.
LevocarnitineA quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia.
CysteamineA cystine depleting agent used to treat the effects of cystinosis.
BetaineA methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels.
Carglumic acidAn analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency.
MetreleptinA leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy.
Drugs & Drug Targets
DrugTargetType
AdemetionineGlycine N-methyltransferasetarget
AdemetionineS-adenosylmethionine decarboxylase proenzymetarget
AdemetionineS-adenosylmethionine synthase isoform type-2target
AdemetionineCystathionine beta-synthasetarget
AdemetionineS-adenosylmethionine synthase isoform type-1target
AdemetionineCytochrome P450 2E1enzyme
AdemetionineCatechol O-methyltransferasetarget
AdemetionineSpermidine synthaseenzyme
AdemetionineCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1target
AdemetionineArsenite methyltransferasetarget
L-GlutamineCTP synthase 1target
L-GlutamineAmidophosphoribosyltransferasetarget
L-GlutamineGlutamine synthetasetarget
L-GlutamineMonocarboxylate transporter 10transporter
L-GlutamineCoagulation factor XIII A chainenzyme
L-GlutamineGlutaminase kidney isoform, mitochondrialenzyme
L-GlutamineGlutaminase liver isoform, mitochondrialenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 2enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 5enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 6enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Kenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 4enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Eenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Zenzyme
L-GlutamineSodium-coupled neutral amino acid transporter 3transporter
L-GlutamineNeutral amino acid transporter B(0)transporter
L-GlutamineGMP synthase [glutamine-hydrolyzing]enzyme
L-GlutamineAsparagine synthetase [glutamine-hydrolyzing]enzyme
L-GlutamineKynurenine--oxoglutarate transaminase 1enzyme
L-GlutaminePhosphoribosylformylglycinamidine synthaseenzyme
L-GlutamineGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrialenzyme
L-GlutamineGlutamine--fructose-6-phosphate aminotransferase [isomerizing] 2enzyme
L-GlutamineCAD proteinenzyme
L-GlutamineGlutamine--tRNA ligaseenzyme
L-GlutamineGlutamine-dependent NAD(+) synthetaseenzyme
L-GlutamineLarge neutral amino acids transporter small subunit 2transporter
L-GlutamineSodium-coupled neutral amino acid transporter 1transporter
L-GlutamineSodium-coupled neutral amino acid transporter 2transporter
L-GlutamineSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
L-GlutamineY+L amino acid transporter 1transporter
L-GlutamineY+L amino acid transporter 2transporter
L-GlutamineLarge neutral amino acids transporter small subunit 1transporter
L-GlutamineB(0,+)-type amino acid transporter 1transporter
LevocarnitineCarnitine O-palmitoyltransferase 1, liver isoformtarget
LevocarnitineSolute carrier family 22 member 4target
LevocarnitineSolute carrier family 22 member 5target
LevocarnitineCarnitine O-acetyltransferasetarget
LevocarnitineMitochondrial carnitine/acylcarnitine carrier protein CACLtarget
LevocarnitineMitochondrial carnitine/acylcarnitine carrier proteintarget
LevocarnitinePeroxisomal carnitine O-octanoyltransferasetarget
LevocarnitineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
LevocarnitineSolute carrier family 22 member 4transporter
LevocarnitineSolute carrier organic anion transporter family member 1B1transporter
LevocarnitineSolute carrier family 22 member 5transporter
LevocarnitineSolute carrier family 22 member 16transporter
LevocarnitineSolute carrier family 22 member 8transporter
LevocarnitineXanthine dehydrogenase/oxidasetarget
LevocarnitineLiver carboxylesterase 1target
LevocarnitineMyeloperoxidasetarget
CysteamineNeuropeptide Y receptor type 2target
CysteamineCystinetarget
CysteamineMyeloperoxidaseenzyme
CysteamineSerum albumincarrier
BetaineCholinesteraseenzyme
BetaineProline dehydrogenase 1, mitochondrialenzyme
BetaineApoptosis regulator Bcl-2target
Carglumic acidCarbamoyl-phosphate synthase [ammonia], mitochondrialtarget
MetreleptinLeptin receptortarget