Guanidine Derivatives

Name
Guanidine Derivatives
Accession Number
DBCAT002226
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
BethanidineFor the treatment of hypertension.
DebrisoquineFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
GuanoxanGuanoxan is an antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage. Guanoxan was approved in the UK but was withdrawn from the market due...
GuanoxabenzNot Annotated
GuanazodineNot Annotated
GuanoclorNot Annotated
GuanethidineAn antihypertensive agent used in the management of moderate and severe hypertension, either alone or as an adjunct, and for the management of renal hypertension.
PinacidilPinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood...
Drugs & Drug Targets
DrugTargetType
BethanidineAlpha-2 adrenergic receptorstarget
BethanidineATP-sensitive inward rectifier potassium channel 1target
BethanidineBeta adrenergic receptortarget
DebrisoquineSodium-dependent noradrenaline transportertarget
DebrisoquineCytochrome P450 2D6enzyme
DebrisoquineP-glycoprotein 1transporter
DebrisoquineCytochrome P450 1A1enzyme
GuanethidineSodium-dependent noradrenaline transportertarget
PinacidilCytochrome P450 3A4enzyme