Antiadrenergic Agents, Peripherally Acting

Name
Antiadrenergic Agents, Peripherally Acting
Accession Number
DBCAT002227
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
BethanidineFor the treatment of hypertension.
PrazosinAn alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
DoxazosinAn alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia.
DebrisoquineFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
IndoraminIndoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
TrimazosinTrimazosin is a sympatholytic alpha blocker.
UrapidilA combination adrenergic antagonist and serotonin agonist given orally for the treatment of essential hypertension and intravenously in hypertensive emergencies.
GuanoxanGuanoxan is an antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage. Guanoxan was approved in the UK but was withdrawn from the market due...
GuanoxabenzNot Annotated
GuanazodineNot Annotated
GuanoclorNot Annotated
GuanethidineAn antihypertensive agent used in the management of moderate and severe hypertension, either alone or as an adjunct, and for the management of renal hypertension.
Drugs & Drug Targets
DrugTargetType
BethanidineAlpha-2 adrenergic receptorstarget
BethanidineATP-sensitive inward rectifier potassium channel 1target
BethanidineBeta adrenergic receptortarget
PrazosinAlpha-1A adrenergic receptortarget
PrazosinAlpha-1B adrenergic receptortarget
PrazosinAlpha-1D adrenergic receptortarget
PrazosinPotassium voltage-gated channel subfamily H member 2target
PrazosinAlpha-1-acid glycoprotein 1carrier
PrazosinSolute carrier family 22 member 1transporter
PrazosinSolute carrier family 22 member 3transporter
PrazosinP-glycoprotein 1transporter
PrazosinATP-binding cassette sub-family G member 2transporter
PrazosinAlpha-2A adrenergic receptortarget
PrazosinAlpha-2B adrenergic receptortarget
PrazosinAlpha-1 adrenergic receptorstarget
DoxazosinAlpha-1A adrenergic receptortarget
DoxazosinAlpha-1D adrenergic receptortarget
DoxazosinHERG human cardiac K+ channeltarget
DoxazosinP-glycoprotein 1transporter
DoxazosinCytochrome P450 2C19enzyme
DoxazosinCytochrome P450 2D6enzyme
DoxazosinSolute carrier family 22 member 1transporter
DoxazosinCytochrome P450 3A4enzyme
DoxazosinAlpha-1B adrenergic receptortarget
DoxazosinCytochrome P450 2C9enzyme
DebrisoquineSodium-dependent noradrenaline transportertarget
DebrisoquineCytochrome P450 2D6enzyme
DebrisoquineP-glycoprotein 1transporter
DebrisoquineCytochrome P450 1A1enzyme
IndoraminAlpha-1A adrenergic receptortarget
GuanethidineSodium-dependent noradrenaline transportertarget