Drugs Used in Benign Prostatic Hypertrophy

Name
Drugs Used in Benign Prostatic Hypertrophy
Accession Number
DBCAT002330
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
AlfuzosinAn alpha-1 adrenergic antagonist used in the symptomatic management of benign prostatic hypertrophy (BPH).
TamsulosinAn alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
DutasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
TerazosinAn alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension.
FinasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
SolifenacinA muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.
SilodosinAn alpha-1 adrenergic receptor antagonist used to treat symptoms associated with benign prostatic hyperplasia (BPH).
MepartricinA medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis.
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
Drugs & Drug Targets
DrugTargetType
AlfuzosinAlpha-1A adrenergic receptortarget
AlfuzosinAlpha-1B adrenergic receptortarget
AlfuzosinAlpha-1D adrenergic receptortarget
AlfuzosinCytochrome P450 3A4enzyme
AlfuzosinP-glycoprotein 1transporter
AlfuzosinAlpha-1 adrenergic receptorstarget
AlfuzosinSerum albumincarrier
AlfuzosinAlpha-1-acid glycoprotein 1carrier
TamsulosinAlpha-1A adrenergic receptortarget
TamsulosinAlpha-1D adrenergic receptortarget
TamsulosinAlpha-1B adrenergic receptortarget
TamsulosinAlpha-1-acid glycoprotein 1carrier
TamsulosinCytochrome P450 2D6enzyme
TamsulosinCytochrome P450 3A4enzyme
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
Dutasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DutasterideSodium-dependent dopamine transportertransporter
DutasterideSynaptic vesicular amine transportertransporter
DutasterideSerum albumincarrier
DutasterideAlpha-1-acid glycoprotein 1carrier
DutasterideCytochrome P450 3A5enzyme
TerazosinAlpha-1A adrenergic receptortarget
TerazosinAlpha-1B adrenergic receptortarget
TerazosinAlpha-1D adrenergic receptortarget
TerazosinPotassium voltage-gated channel subfamily H member 2target
TerazosinPotassium voltage-gated channel subfamily H member 6target
TerazosinPotassium voltage-gated channel subfamily H member 7target
TerazosinP-glycoprotein 1transporter
TerazosinTransforming growth factor beta-1target
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
FinasterideCytochrome P450 3A4enzyme
Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
Finasteride3-oxo-5-beta-steroid 4-dehydrogenasetarget
FinasterideCytochrome P450 3A5enzyme
FinasterideCytochrome P450 3A7enzyme
FinasterideSolute carrier family 12 member 5transporter
SolifenacinMuscarinic acetylcholine receptor M3target
SolifenacinMuscarinic acetylcholine receptor M1target
SolifenacinCytochrome P450 3A4enzyme
SolifenacinMuscarinic acetylcholine receptor M2target
SolifenacinMuscarinic acetylcholine receptor M4target
SolifenacinMuscarinic acetylcholine receptor M5target
Solifenacinalpha1-acid glycoproteincarrier
SolifenacinCytochrome P450 1A1enzyme
SolifenacinCytochrome P450 2D6enzyme
SilodosinAlpha-1D adrenergic receptortarget
SilodosinCytochrome P450 3A4enzyme
SilodosinP-glycoprotein 1transporter
SilodosinMultidrug resistance protein 3transporter
SilodosinAlpha-1A adrenergic receptortarget
SilodosinAlpha-1B adrenergic receptortarget
SilodosinUDP-glucuronosyltransferase 2B7enzyme
SilodosinAldehyde dehydrogenase, mitochondrialenzyme
SilodosinAlcohol dehydrogenase [NADP(+)]enzyme
SilodosinHERG human cardiac K+ channeltarget
TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
TadalafilCytochrome P450 3A4enzyme
TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
TadalafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget