Propulsives

Name
Propulsives
Accession Number
DBCAT002422
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
CisaprideA medication used to treat heartburn associated with GERD.
DomperidoneA dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
AlizaprideA dopamine antagonist used to prevent nausea and vomiting associated with medical procedures, surgeries, and cancer therapies.
ItoprideAn acetylcholine esterase inhibitor and dopamine D2 receptor antagonist used to treat symptoms of functional dyspepsia such as nausea and vomiting.
BromoprideA substituted benzamide, closely related to metoclopramide, used as an antiemetic.
CleboprideA dopamine antagonist used to treat symptoms associated with functional gastrointestinal disorders. Clebopride may also be used to treat nausea and vomiting associated with chemotherapy.
CinitaprideA benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying.
MosaprideA prokinetic 5-HT4 receptor agonist used to stimulate gastric motility.
Drugs & Drug Targets
DrugTargetType
Cisapride5-hydroxytryptamine receptor 4target
Cisapride5-hydroxytryptamine receptor 3Atarget
CisapridePotassium voltage-gated channel subfamily H member 2target
Cisapride5-hydroxytryptamine receptor 2Atarget
CisaprideCytochrome P450 3A4enzyme
CisaprideCytochrome P450 3A5enzyme
CisaprideCytochrome P450 3A7enzyme
CisaprideCytochrome P450 2A6enzyme
CisaprideCytochrome P450 2B6enzyme
CisaprideCytochrome P450 2C19enzyme
CisaprideCytochrome P450 2C8enzyme
CisaprideCytochrome P450 2C9enzyme
CisaprideCytochrome P450 2D6enzyme
DomperidoneDopamine D2 receptortarget
DomperidoneCytochrome P450 3A4enzyme
DomperidoneCytochrome P450 3A5enzyme
DomperidoneCytochrome P450 3A7enzyme
DomperidoneP-glycoprotein 1transporter
DomperidoneCytochrome P450 1A2enzyme
DomperidoneCytochrome P450 2B6enzyme
DomperidoneCytochrome P450 2C8enzyme
DomperidoneCytochrome P450 2D6enzyme
DomperidoneDopamine D3 receptortarget
MetoclopramideMuscarinic acetylcholine receptor M1target
MetoclopramideDopamine D2 receptortarget
MetoclopramideCytochrome P450 2D6enzyme
Metoclopramide5-hydroxytryptamine receptor 4target
Metoclopramide5-hydroxytryptamine receptor 3Atarget
MetoclopramideCytochrome P450 3A4enzyme
MetoclopramideCytochrome P450 1A2enzyme
MetoclopramideP-glycoprotein 1transporter
MetoclopramideAlpha-1-acid glycoprotein 1carrier
AlizaprideDopamine D2 receptortarget
ItoprideDopamine D2 receptortarget
ItoprideAcetylcholinesterasetarget
BromoprideDopamine D2 receptortarget
Cinitapride5-hydroxytryptamine receptor 1Atarget
Cinitapride5-hydroxytryptamine receptor 4target
Cinitapride5-hydroxytryptamine receptor 2Atarget