Clebopride
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Name
- Clebopride
- Accession Number
- DB13511
- Description
- Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 373.88
Monoisotopic: 373.1557047 - Chemical Formula
- C20H24ClN3O2
- Synonyms
- Cleboprida
- Clebopride
- External IDs
- LAS 9273
Pharmacology
- Accelerate your drug discovery research with the industry’s only fully connected ADMET dataset, ideal for:Accelerate your drug discovery research with our fully connected ADMET dataset
- Indication
- Not Available
- Associated Conditions
- Contraindications & Blackbox Warnings
- Contraindications & Blackbox WarningsWith our commercial data, access important information on dangerous risks, contraindications, and adverse effects.Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects
- Pharmacodynamics
- Not Available
- Mechanism of action
- Not Available
- Absorption
- Not Available
- Volume of distribution
- Not Available
- Protein binding
- Not Available
- Metabolism
- Not Available
- Route of elimination
- Not Available
- Half-life
- Not Available
- Clearance
- Not Available
- Adverse Effects
- Reduce medical errorsand improve treatment outcomes with our comprehensive & structured data on drug adverse effects.Reduce medical errors & improve treatment outcomes with our adverse effects data
- Toxicity
- Not Available
- Affected organisms
- Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareApomorphine The therapeutic efficacy of Apomorphine can be decreased when used in combination with Clebopride. Aripiprazole The therapeutic efficacy of Aripiprazole can be decreased when used in combination with Clebopride. Benzatropine The risk or severity of adverse effects can be increased when Clebopride is combined with Benzatropine. Brexpiprazole The therapeutic efficacy of Brexpiprazole can be decreased when used in combination with Clebopride. Bromocriptine The therapeutic efficacy of Bromocriptine can be decreased when used in combination with Clebopride. Cabergoline The therapeutic efficacy of Cabergoline can be decreased when used in combination with Clebopride. Deutetrabenazine The risk or severity of adverse effects can be increased when Clebopride is combined with Deutetrabenazine. Dihydroergocornine The therapeutic efficacy of Dihydroergocornine can be decreased when used in combination with Clebopride. Dihydroergotamine The therapeutic efficacy of Dihydroergotamine can be decreased when used in combination with Clebopride. Dopexamine The therapeutic efficacy of Dopexamine can be decreased when used in combination with Clebopride. Improve patient outcomesBuild effective decision support tools with the industry’s most comprehensive drug-drug interaction checker.Learn more - Food Interactions
- Not Available
Products
- Comprehensive & structured drug product infoFrom application numbers to product codes, connect different identifiers through our commercial datasets.Easily connect various identifiers back to our datasets
Categories
- ATC Codes
- A03FA06 — Clebopride
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as n-benzylpiperidines. These are heterocyclic Compounds containing a piperidine ring conjugated to a benzyl group through one nitrogen ring atom.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Piperidines
- Sub Class
- Benzylpiperidines
- Direct Parent
- N-benzylpiperidines
- Alternative Parents
- Aminophenyl ethers / Methoxyanilines / Phenylmethylamines / Phenoxy compounds / Anisoles / Methoxybenzenes / Benzylamines / Alkyl aryl ethers / Aralkylamines / Chlorobenzenes show 9 more
- Substituents
- Alkyl aryl ether / Amine / Aminophenyl ether / Aniline or substituted anilines / Anisole / Aralkylamine / Aromatic heteromonocyclic compound / Aryl chloride / Aryl halide / Azacycle show 27 more
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- Not Available
Chemical Identifiers
- UNII
- I0A84520Y9
- CAS number
- 55905-53-8
- InChI Key
- BVPWJMCABCPUQY-UHFFFAOYSA-N
- InChI
- InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25)
- IUPAC Name
- 4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide
- SMILES
- COC1=CC(N)=C(Cl)C=C1C(=O)NC1CCN(CC2=CC=CC=C2)CC1
References
- General References
- External Links
- ChemSpider
- 2678
- BindingDB
- 50132693
- 21224
- ChEBI
- 92309
- ChEMBL
- CHEMBL325109
- ZINC
- ZINC000000608261
- Wikipedia
- Clebopride
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet, film coated Oral Tablet Oral Injection, solution Intramuscular; Intravenous 1 MG/2ML Syrup Oral 0.5 MG/5ML Tablet Oral 0.5 MG - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0198 mg/mL ALOGPS logP 2.69 ALOGPS logP 2.42 ChemAxon logS -4.3 ALOGPS pKa (Strongest Acidic) 14.61 ChemAxon pKa (Strongest Basic) 8.52 ChemAxon Physiological Charge 1 ChemAxon Hydrogen Acceptor Count 4 ChemAxon Hydrogen Donor Count 2 ChemAxon Polar Surface Area 67.59 Å2 ChemAxon Rotatable Bond Count 5 ChemAxon Refractivity 106.07 m3·mol-1 ChemAxon Polarizability 39.81 Å3 ChemAxon Number of Rings 3 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter Yes ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created on June 23, 2017 20:43 / Updated on February 21, 2021 18:54