DPP-IV Inhibitors
- Name
- DPP-IV Inhibitors
- Accession Number
- DBCAT002653 (DBCAT001315, DBCAT002433, DBCAT003757)
- Description
Compounds that suppress the degradation of INCRETINS by blocking the action of DIPEPTIDYL-PEPTIDASE IV. This helps to correct the defective INSULIN and GLUCAGON secretion characteristic of TYPE 2 DIABETES MELLITUS by stimulating insulin secretion and suppressing glucagon release.
- ATC Classification
- Drugs
Drug Drug Description Alogliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. AMG-222 Investigated for use/treatment in diabetes mellitus type 2. Anagliptin Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors. Bisegliptin Investigated for use/treatment in diabetes mellitus type 2. Carmegliptin Carmegliptin has been used in trials studying the treatment of Diabetes Mellitus Type 2. Dutogliptin Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II. Evogliptin Evogliptin has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2. Gemigliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Gosogliptin Gosogliptin has been used in trials studying the treatment of Renal Insufficiency, Chronic. Linagliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Omarigliptin Omarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency. Saxagliptin An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. Sitagliptin An oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. Teneligliptin Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus. Vildagliptin A once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus.