Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme

Name
Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme
Accession Number
DBCAT003275
Description

Not Available

Drugs
DrugDrug Description
LaronidaseA form of recombinant human alpha-L-iduronidase used to treat Hurler and Hurler-Scheie forms of mucopolysaccharidosis, a genetic deficiency of alpha-L-iduronidase.
IdursulfaseA purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients.
GalsulfaseA recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme.
Elosulfase alfaA lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A.
Drugs & Drug Targets
DrugTargetType
LaronidaseIduronic acidtarget
IdursulfasePerilipin-3target
IdursulfaseDermatan sulfatetarget
IdursulfaseHeparan sulfatetarget
GalsulfasePerilipin-3target
GalsulfaseDermatan sulfatetarget