Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme
- Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme
- Accession Number
Drug Drug Description Laronidase A form of recombinant human alpha-L-iduronidase used to treat Hurler and Hurler-Scheie forms of mucopolysaccharidosis, a genetic deficiency of alpha-L-iduronidase. Idursulfase A purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients. Galsulfase A recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme. Elosulfase alfa A lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A.
- Drugs & Drug Targets
Drug Target Type Laronidase Iduronic acid target Idursulfase Perilipin-3 target Idursulfase Dermatan sulfate target Idursulfase Heparan sulfate target Galsulfase Perilipin-3 target Galsulfase Dermatan sulfate target