Nonergot-derivative Dopamine Receptor Agonists

Nonergot-derivative Dopamine Receptor Agonists
Accession Number
DBCAT003649  (DBCAT003313)

Not Available

DrugDrug Description
ApomorphineA morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
RotigotineA non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome.
RopiniroleA non-ergoline dopamine agonist used to treat the symptoms of Parkinson's disease and Restless Legs Syndrome.
PramipexoleA non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS).
DihydrexidineDihydrexidine has been used in trials studying the treatment of SPD, Cocaine-Related Disorders, and Schizotypal Personality Disorder.
PiribedilA dopamine agonist used with or without levodopa in the treatment of Parkinson's disease.
DopexamineDopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
Drugs & Drug Targets
ApomorphineDopamine D2 receptortarget
ApomorphineDopamine D1 receptortarget
ApomorphineDopamine D4 receptortarget
ApomorphineDopamine D3 receptortarget
ApomorphineDopamine D5 receptortarget
ApomorphineAlpha-2C adrenergic receptortarget
ApomorphineAlpha-2B adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 2Ctarget
Apomorphine5-hydroxytryptamine receptor 1Atarget
Apomorphine5-hydroxytryptamine receptor 2Atarget
Apomorphine5-hydroxytryptamine receptor 2Btarget
ApomorphineAlpha-2A adrenergic receptortarget
Apomorphine5-hydroxytryptamine receptor 1Dtarget
Apomorphine5-hydroxytryptamine receptor 1Btarget
ApomorphineCatechol O-methyltransferaseenzyme
ApomorphineSulfotransferase 1A1enzyme
ApomorphineSulfotransferase 1A2enzyme
ApomorphineSulfotransferase 1A3/1A4enzyme
ApomorphineEstrogen sulfotransferaseenzyme
ApomorphineSulfotransferase family cytosolic 1B member 1enzyme
ApomorphineCytochrome P450 2B6enzyme
ApomorphineCytochrome P450 2C8enzyme
ApomorphineCytochrome P450 3A4enzyme
ApomorphineCytochrome P450 3A5enzyme
ApomorphineUDP-glucuronosyltransferases (UGTs)enzyme
ApomorphineSerum albumincarrier
ApomorphineSynaptic vesicular amine transportertransporter
RotigotineDopamine D3 receptortarget
RotigotineDopamine D5 receptortarget
RotigotineDopamine D4 receptortarget
RotigotineDopamine D2 receptortarget
Rotigotine5-hydroxytryptamine receptor 1Atarget
RotigotineDopamine D1 receptortarget
RotigotineCytochrome P450 2D6enzyme
RotigotineCytochrome P450 3A4enzyme
RotigotineAlpha-2B adrenergic receptortarget
RotigotineCytochrome P450 2C19enzyme
RopiniroleDopamine D2 receptortarget
RopiniroleDopamine D3 receptortarget
RopiniroleDopamine D4 receptortarget
RopiniroleCytochrome P450 1A2enzyme
RopiniroleAlpha adrenergic receptortarget
PramipexoleDopamine D3 receptortarget
PramipexoleDopamine D4 receptortarget
PramipexoleDopamine D2 receptortarget
Pramipexole5-hydroxytryptamine receptor 1Atarget
PramipexoleAlpha-2A adrenergic receptortarget
PramipexoleSolute carrier family 22 member 2transporter
PramipexoleSolute carrier family 22 member 1transporter
PramipexoleSolute carrier family 22 member 3transporter
DihydrexidineDopamine D1 receptortarget
PiribedilDopamine D2 receptortarget
PiribedilDopamine D3 receptortarget