Miscellaneous Anxiolytics Sedatives and Hypnotics

Name
Miscellaneous Anxiolytics Sedatives and Hypnotics
Accession Number
DBCAT003678
Description

Not Available

Drugs
DrugDrug Description
BuspironeAn anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression.
Chloral hydrateA mild hypnotic used for experimental purposes that was previously used for the treatment of insomnia.
DexmedetomidineAn alpha-2 agonist used for sedation during various procedures.
DroperidolA butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting.
EszopicloneA sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep.
HydroxyzineAn antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria.
PromethazineA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
SuvorexantA orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance.
ValerianA plant used in some non-prescription natural health products.
ZaleplonA sedative used for short term treatment of insomnia in adults.
ZolpidemA sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency.
ZopicloneA nonbenzodiazepine hypnotic used for the short-term management of insomnia.
Drugs & Drug Targets
DrugTargetType
BuspironeAlpha-1 adrenergic receptorstarget
BuspironeDopamine receptor D4target
BuspironeDopamine receptor D3target
BuspironeAlpha-1-acid glycoprotein 1carrier
Buspirone5-hydroxytryptamine receptor 1Atarget
BuspironeDopamine receptor D2target
BuspironeCytochrome P450 3A4enzyme
BuspironeCytochrome P450 3A5enzyme
BuspironeCytochrome P450 3A7enzyme
BuspironeATP-dependent translocase ABCB1transporter
BuspironeCytochrome P450 2D6enzyme
BuspironeAlbumincarrier
Chloral hydrateAldehyde dehydrogenase, mitochondrialenzyme
Chloral hydrateAlcohol dehydrogenaseenzyme
Chloral hydrateNADP-dependent fatty aldehyde dehydrogenasetarget
Chloral hydrateAldehyde dehydrogenase, mitochondrialtarget
Chloral hydrateAlcohol dehydrogenase 1Aenzyme
Chloral hydrateAldo-keto reductase family 1 member B1enzyme
Chloral hydrateAldehyde dehydrogenase 1A1enzyme
Chloral hydrateCytochrome P450 2F1enzyme
Chloral hydrateCytochrome P450 2B1enzyme
Chloral hydrateCytochrome P450 2E1enzyme
Chloral hydrateAldo-keto reductase family 1 member A1enzyme
DexmedetomidineAlpha-2A adrenergic receptortarget
DexmedetomidineCytochrome P450 2E1enzyme
DexmedetomidineCytochrome P450 1A2enzyme
DexmedetomidineCytochrome P450 1A1enzyme
DexmedetomidineCytochrome P450 2D6enzyme
DexmedetomidineAlpha-2 adrenergic receptorstarget
Droperidol5-hydroxytryptamine receptor 2Atarget
DroperidolAlpha-1A adrenergic receptortarget
DroperidolDopamine receptor D2target
EszopicloneTranslocator proteintarget
EszopicloneGABA(A) Receptortarget
EszopicloneCytochrome P450 2C8enzyme
EszopicloneGamma-aminobutyric acid receptor subunit alpha-5target
EszopicloneGamma-aminobutyric acid receptor subunit alpha-3target
EszopicloneGamma-aminobutyric acid receptor subunit alpha-2target
EszopicloneGamma-aminobutyric acid receptor subunit alpha-1target
EszopicloneCytochrome P450 3A4enzyme
HydroxyzineAlbumincarrier
HydroxyzineATP-dependent translocase ABCB1transporter
HydroxyzineVoltage-gated inwardly rectifying potassium channel KCNH2target
HydroxyzineCytochrome P450 3A5enzyme
HydroxyzineCytochrome P450 3A4enzyme
HydroxyzineCytochrome P450 2D6enzyme
HydroxyzineHistamine H1 receptortarget
PromethazineNMDA receptortarget
PromethazineCalmodulintarget
PromethazineAlbumincarrier
PromethazineATP-binding cassette sub-family C member 4transporter
PromethazineDopamine receptor D2target
PromethazineHistamine H1 receptortarget
PromethazineMuscarinic acetylcholine receptor M4target
PromethazineMuscarinic acetylcholine receptor M1target
PromethazineMuscarinic acetylcholine receptor M5target
PromethazineMuscarinic acetylcholine receptor M2target
PromethazineMuscarinic acetylcholine receptor M3target
PromethazineCytochrome P450 2D6enzyme
PromethazineCytochrome P450 2B6enzyme
PromethazineATP-dependent translocase ABCB1transporter
PromethazineCytochrome P450 2C9enzyme
PromethazineHistamine H2 receptortarget
PromethazineAlpha adrenergic receptortarget
PromethazineP2 Purinoceptorstarget
PromethazineVoltage-gated sodium channel alpha subunittarget
PromethazineVoltage-gated Potassium Channelstarget
PromethazineATP-binding cassette sub-family C member 3transporter
SuvorexantATP-dependent translocase ABCB1transporter
SuvorexantOrexin/Hypocretin receptor type 1target
SuvorexantOrexin receptor type 2target
SuvorexantCytochrome P450 3A4enzyme
ZaleplonCytochrome P450 3A5enzyme
ZaleplonCytochrome P450 3A7enzyme
ZaleplonCytochrome P450 3A4enzyme
ZaleplonGamma-aminobutyric acid receptor subunit alpha-1target
ZaleplonAldehyde oxidaseenzyme
ZolpidemGamma-aminobutyric acid receptor subunit gamma-3target
ZolpidemGamma-aminobutyric acid receptor subunit gamma-2target
ZolpidemCytochrome P450 2D6enzyme
ZolpidemCytochrome P450 2C19enzyme
ZolpidemCytochrome P450 2C9enzyme
ZolpidemGamma-aminobutyric acid receptor subunit alpha-3target
ZolpidemGamma-aminobutyric acid receptor subunit alpha-2target
ZolpidemCytochrome P450 1A2enzyme
ZolpidemCytochrome P450 3A4enzyme
ZolpidemGamma-aminobutyric acid receptor subunit alpha-1target
ZopicloneTranslocator proteintarget
ZopicloneCytochrome P450 2C8enzyme
ZopicloneCytochrome P450 2C9enzyme
ZopicloneCytochrome P450 3A4enzyme
ZopicloneProstaglandin G/H synthase 1enzyme
ZopicloneGamma-aminobutyric acid receptor subunit alpha-1target
ZopicloneGamma-aminobutyric acid receptor subunit alpha-2target
ZopicloneGamma-aminobutyric acid receptor subunit alpha-3target
ZopicloneGamma-aminobutyric acid receptor subunit alpha-5target