Tryptophan Hydroxylase Inhibitor

Name
Tryptophan Hydroxylase Inhibitor
Accession Number
DBCAT003820
Description

Not Available

Drugs
DrugDrug Description
TelotristatA tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
Telotristat ethylA tryptophan hydroxylase inhibitor that is used to treat carcinoid syndrome diarrhea.
Drugs & Drug Targets
DrugTargetType
Telotristat ethylTryptophan 5-hydroxylase 2target
Telotristat ethylTryptophan 5-hydroxylase 1target
Telotristat ethylP-glycoprotein 1transporter
Telotristat ethylCytochrome P450 3A4enzyme
Telotristat ethylCytochrome P450 2B6enzyme
Telotristat ethylLiver carboxylesterase 1enzyme
Telotristat ethylATP-binding cassette sub-family G member 2carrier
Telotristat ethylCocaine esteraseenzyme
Telotristat ethylUDP-glucuronosyltransferase 2B4enzyme
Telotristat ethylUDP-glucuronosyltransferase 2B7enzyme
Telotristat ethylCytochrome P450 2C9enzyme
Telotristat ethylCytochrome P450 2C19enzyme
Telotristat ethylCytochrome P450 2D6enzyme
Telotristat ethylCytochrome P450 2C8enzyme