OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index
- Name
- OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index
- Accession Number
- DBCAT003983
- Description
Not Available
- Drugs
Drug Drug Description Valproic acid An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. Clofarabine A purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old. Methotrexate An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis. Mercaptopurine An antineoplastic agent used to treat acute lymphocytic leukemia. Baricitinib A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. Pemetrexed A folate analog used to treat mesothelioma and non-small cell lung cancer. - Drugs & Drug Targets