Angiotensin II receptor antagonists

Name
Angiotensin II receptor antagonists
Accession Number
DBCAT005393
Description

Not Available

Drugs
DrugDrug Description
ValsartanAn angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.
OlmesartanAn angiotensin receptor blocker (ARB) used in the treatment of hypertension.
LosartanAn angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
Candesartan cilexetilAn angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy.
EprosartanAn ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
TelmisartanAn ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
IrbesartanAn angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure.
Azilsartan medoxomilAn angiotensin II receptor blocker used to treat hypertension alone or in combination with other antihypertensive agents, such as chlorthalidone.
ForasartanFor the treatment of hypertension.
SaprisartanSaprisartan is used in the treatment of hypertension and heart failure.
CandesartanAn angiotensin-receptor blocker indicated in the treatment of hypertension.
Drugs & Drug Targets
DrugTargetType
ValsartanType-1 angiotensin II receptortarget
ValsartanCytochrome P450 2C9enzyme
ValsartanSolute carrier organic anion transporter family member 1B3transporter
ValsartanSolute carrier organic anion transporter family member 1B1transporter
ValsartanCanalicular multispecific organic anion transporter 1transporter
OlmesartanType-1 angiotensin II receptortarget
OlmesartanCanalicular multispecific organic anion transporter 1transporter
OlmesartanSolute carrier organic anion transporter family member 1B3transporter
OlmesartanSolute carrier organic anion transporter family member 1B1transporter
OlmesartanBile salt export pumptransporter
LosartanType-1 angiotensin II receptortarget
LosartanCytochrome P450 3A4enzyme
LosartanCytochrome P450 2C9enzyme
LosartanP-glycoprotein 1transporter
LosartanSolute carrier family 22 member 6transporter
LosartanUDP-glucuronosyltransferase 1-1enzyme
LosartanUDP-glucuronosyltransferase 1-3enzyme
LosartanUDP-glucuronosyltransferase 1-10enzyme
LosartanUDP-glucuronosyltransferase 2B7enzyme
LosartanUDP-glucuronosyltransferase 2B17enzyme
LosartanCytochrome P450 2C19enzyme
LosartanSerum albumincarrier
LosartanSolute carrier family 22 member 12transporter
LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
LosartanBile salt export pumptransporter
LosartanCytochrome P450 2C8enzyme
Candesartan cilexetilType-1 angiotensin II receptortarget
Candesartan cilexetilCytochrome P450 2C8enzyme
Candesartan cilexetilCytochrome P450 2C9enzyme
Candesartan cilexetilP-glycoprotein 1transporter
Candesartan cilexetilUDP-glucuronosyltransferase 1-3enzyme
Candesartan cilexetilProstaglandin G/H synthase 1enzyme
EprosartanType-1 angiotensin II receptortarget
EprosartanCanalicular multispecific organic anion transporter 1transporter
TelmisartanType-1 angiotensin II receptortarget
TelmisartanPeroxisome proliferator-activated receptor gammatarget
TelmisartanP-glycoprotein 1transporter
TelmisartanCanalicular multispecific organic anion transporter 1transporter
TelmisartanATP-binding cassette sub-family G member 2transporter
TelmisartanCytochrome P450 2C19enzyme
TelmisartanBile salt export pumptransporter
TelmisartanUDP-glucuronosyltransferase 1-3enzyme
IrbesartanType-1 angiotensin II receptortarget
IrbesartanTranscription factor AP-1target
IrbesartanCytochrome P450 2C9enzyme
IrbesartanCytochrome P450 2C8enzyme
IrbesartanUDP-glucuronosyltransferase 1-3enzyme
IrbesartanProstaglandin G/H synthase 1enzyme
IrbesartanCytochrome P450 3A4enzyme
IrbesartanSerum albumincarrier
Irbesartanalpha1-acid glycoproteincarrier
Azilsartan medoxomilType-1 angiotensin II receptortarget
Azilsartan medoxomilSerum albumincarrier
Azilsartan medoxomilCytochrome P450 2C9enzyme
Azilsartan medoxomilCytochrome P450 2C8enzyme
Azilsartan medoxomilCytochrome P450 2B6enzyme
Azilsartan medoxomilP-glycoprotein 1transporter
ForasartanType-1 angiotensin II receptortarget
SaprisartanType-1 angiotensin II receptortarget
CandesartanType-1 angiotensin II receptortarget
CandesartanCytochrome P450 2C8enzyme
CandesartanCytochrome P450 2C9enzyme
CandesartanP-glycoprotein 1transporter
CandesartanUDP-glucuronosyltransferase 1-3enzyme
CandesartanProstaglandin G/H synthase 1enzyme
CandesartanSolute carrier organic anion transporter family member 1B1transporter