Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension. Forasartan competes with angiotensin II for binding at the AT1 receptor subtype. As... As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance.
- Mechanism
- Curator reviewed
Forasartan competes with angiotensin II for binding at the AT1 receptor subtype. As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance. Also, since angiotensin causes vasoconstriction, the inhibition of this receptor decreases vasoconstriction, which consequently also decreases vascular resistnace.
- Primary indication
- For the treatment of hypertension.Curator reviewed
- Formula / weight
- C23H28N8 · 416.522 g/mol (avg)
- Code names
- SC-52458
Resolves to
YONOBYIBNBCDSJ-UHFFFAOYSA-NSMILESCCCCC1=NN(CC2=CN=C(C=C2)C2=CC=CC=C2C2=NNN=N2)C(CCCC)=N1What you can answer from here — as of September 20, 2026
Which drugs share a target with Forasartan, and which of those have an active Phase 3 trial?
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