Mast Cell Stabilizers

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Name: Mast Cell Stabilizers
Accession Number: DBCAT002745
Description: Substances that reduce or suppress INFLAMMATION.
Drugs: Drug Drug Description
Bepotastine An ophthalmic H1 antagonist used to treat itchiness associated with allergic conjunctivitis.
Cromoglicic acid A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions.
Lodoxamide An ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
Nedocromil A pyrano quinoline used to treat allergic conjunctivitis.
Olopatadine A histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis.
Pemirolast A medication used to treat allergies such as hay fever and allergic conjunctivitis.
Spaglumic acid The β-aspartyl isoform of N-Acetyl-l-aspartylglutamate, a naturally occurring neurotransmitter, used in allergic eye conditions due to its ability to stabilize mast cells.
Drugs & Drug Targets: Drug Target Type
Bepotastine Histamine H1 receptor target
Cromoglicic acid Protein S100-P target
Cromoglicic acid Heat shock protein HSP 90-alpha target
Lodoxamide G protein-coupled receptor 35 target
Lodoxamide Xanthine dehydrogenase/oxidase target
Nedocromil Cysteinyl leukotriene receptor 1 target
Nedocromil Cysteinyl leukotriene receptor 2 target
Nedocromil Prostaglandin D2 receptor target
Nedocromil N-formyl peptide receptor 1 target
Olopatadine Histamine H1 receptor target
Olopatadine Protein S100-A1 target
Olopatadine Protein S100-A12 target
Olopatadine Protein S100-B target
Olopatadine Protein S100-A13 target
Olopatadine Protein S100-A2 target
Olopatadine Cytochrome P450 3A4 enzyme
Olopatadine Albumin carrier
Olopatadine Flavin-containing monooxygenase 1 enzyme
Olopatadine Flavin-containing monooxygenase 3 enzyme
Olopatadine ATP-dependent translocase ABCB1 transporter
Olopatadine Histamine H2 receptor target
Olopatadine Histamine H3 receptor target
Pemirolast Histamine H1 receptor target
Spaglumic acid Proton-coupled amino acid transporter 1 transporter
Spaglumic acid Glutamate carboxypeptidase 2 target

Drug	Drug Description
Bepotastine	An ophthalmic H1 antagonist used to treat itchiness associated with allergic conjunctivitis.
Cromoglicic acid	A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions.
Lodoxamide	An ophthalmic agent used for the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
Nedocromil	A pyrano quinoline used to treat allergic conjunctivitis.
Olopatadine	A histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis.
Pemirolast	A medication used to treat allergies such as hay fever and allergic conjunctivitis.
Spaglumic acid	The β-aspartyl isoform of N-Acetyl-l-aspartylglutamate, a naturally occurring neurotransmitter, used in allergic eye conditions due to its ability to stabilize mast cells.

Mast Cell Stabilizers

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