Flatulence (DBCOND0004513)

Identifiers

Synonyms

Gas / Gases / Gas (state of matter) / Gaseous substance (substance) / Abdominal wind / Gaseousness / Flatulence symptom (context-dependent category) / Flatus / Flatus (function) / Passing flatus (finding) / Wind / Excessive upper gastrointestinal gas (finding) / Gas (basic dose form) / Beta-hemolytic Streptococcus, group A (organism) / Excessive flatulence

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Activated charcoal	A gastric decontamination agent used in emergency clinical settings as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons.	No drug targets
Alginic acid	Indicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress .	No drug targets
Aluminium glycinate	A medication indicated to treat heartburn, indigestion, acid reflux, ulcers, and gas.	No drug targets
Aluminum hydroxide	An antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.	No drug targets
Alverine	A smooth muscle relaxant used to relieve abdominal pain associated with gastrointestinal conditions like heartburn, flatulence, and Irritable Bowel Syndrome.	5-hydroxytryptamine receptor 1Atarget
Anise oil	Not Annotated	No drug targets
Bacillus clausii	A probiotic used to restore normal gastrointestinal flora.	No drug targets
Bismuth subsalicylate	An antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.	Albumincarrier Serotransferrincarrier
Bromopride	A substituted benzamide, closely related to metoclopramide, used as an antiemetic.	D(2) dopamine receptortarget
Cinitapride	A benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying.	5-hydroxytryptamine receptor 1Atarget 5-hydroxytryptamine receptor 4target 5-hydroxytryptamine receptor 2Atarget
Dimethicone	An ingredient used to treat dry and irritated eyes.	No drug targets
Gentiana lutea extract	A medication used to treat bloating and gas.	No drug targets
Magnesium hydroxide	An inorganic compound used as a laxative and antacid.	No drug targets
Magnesium trisilicate	An antacid used for the symptomatic treatment of peptic ulcers.	No drug targets
Metoclopramide	An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.	Muscarinic acetylcholine receptor M1target D(2) dopamine receptortarget Cytochrome P450 2D6enzyme 5-hydroxytryptamine receptor 4target 5-hydroxytryptamine receptor 3Atarget Cytochrome P450 3A4enzyme Cytochrome P450 1A2enzyme ATP-dependent translocase ABCB1transporter Alpha-1-acid glycoprotein 1carrier
Pancrelipase	A purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis.	Dietary fattarget Dietary proteintarget Dietary starchtarget
Peppermint oil	An ingredient used in a variety of natural health products and is not an approved medication.	Cytochrome P450 1A2enzyme Cytochrome P450 3A4enzyme
Pinaverium	A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract.	Voltage-dependent L-type calcium channel subunit alpha-1Starget Cytochrome P450 3A4enzyme
Silodrate	Not Annotated	No drug targets
Simethicone	An anti-flatulence agent used to relieve pressure, bloating, and symptoms referred to as gas.	No drug targets

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04684849	Assessment and Validation of Electronic Gas and Bloating Diary	No drug interventions	Not Available	Not Available	unknown_status
NCT02277431	Probiotic Supplementation Among Adults With Recurrent Gastrointestinal Symptoms	No drug interventions	other	2 / 3	completed
NCT04243187	Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption	No drug interventions	other	Not Available	unknown_status
NCT05247333	Implementation of a Minor Ailment Service in Community Pharmacy Practice	No drug interventions	health_services_research	Not Available	completed
NCT01677715	Study of Yili Mei Yi Tian Active Lactobacillus Drink to Improve Immunity and Digestive System	No drug interventions	prevention	Not Available	completed
NCT00881322	A Study on Intestinal Gas Symptoms to Evaluate the Effects of Gas Defense in Otherwise Healthy Adult	No drug interventions	Not Available	Not Available	completed
NCT02693782	Fabulous Fibre Study - Effect of Wheat Bran Extract on Gut and General Health in Healthy Aging Subjects (FFS)	No drug interventions	basic_science	Not Available	completed
NCT03134469	Efficacy of Probiotics on Excessive Gas Accumulation	No drug interventions	prevention	Not Available	completed
NCT01682798	Study of Yili "Changqing" Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System	No drug interventions	prevention	Not Available	completed
NCT03076411	Pepsin in Patients With Functional Dyspepsia	Amino acids Pepsin	Not Available	Not Available	completed
NCT01291446	Effect of Diet on Intestinal Gas Production and Evacuation in Healthy Subjects and Flatulent Patients	No drug interventions	screening	Not Available	completed