Aluminum hydroxide is an antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions.
- Mechanism
- Curator reviewed
Aluminum hydroxide is a basic inorganic salt that acts by neutralizing hydrochloric acid in gastric secretions. Aluminum hydroxide is slowly solubilized in the stomach and reacts with hydrochloric acid to form aluminum chloride and water. It also inhibits the action of pepsin by increasing the pH and via adsorption. Cytoprotective effects may occur through increases in bicarbonate ion (HCO3-) and prostaglandins.
- Primary indication
- For relief of heartburn and acid indigestion.Curator reviewed · 43 structured indications
- Formula / weight
- AlH3O3 · 78.0036 g/mol (avg)
- First approval
- Canada, 1997 · United States, 2011
- Also known as
- Aluminium hydroxide · Aluminum hydroxide, dried · Dried aluminium hydroxide · Dried aluminum hydroxide gel
- Code names
- NSC-664400
- Brand names
Resolves to
WNROFYMDJYEPJX-UHFFFAOYSA-KSMILES[OH-].[OH-].[OH-].[Al+3]What you can answer from here — as of September 23, 2026
Which drugs share a target with Aluminum hydroxide, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account