Malignant Hyperthermia (DBCOND0004999)
Identifiers
- Synonyms
- Hyperthermia, Malignant / Hyperthermia malignant / Malignant hyperthermia / Malignant hyperthermia due to anesthesia / Malignant hyperpyrexia caused by anesthetic (disorder) / Malignant hyperpyrexia / Fever malignant / Hyperpyrexia malignant / Malignant hyperthermia (disorder)
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Dantrolene A direct-acting skeletal muscle relaxant used for the treatment of management of the fulminant hypermetabolism of skeletal muscle leading to malignant hyperthermia crisis.- Ryanodine receptor 1target
- Thyroxine-binding globulincarrier
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT03964870 Spanish Registry of RYR1 and CACNA1S Polymorphisms No drug interventions Not Available Not Available unknown_status NCT04610619 Multisystem Features of Malignant Hyperthermia or Rhabdomyolysis Related to RYR1 Variants No drug interventions Not Available Not Available unknown_status NCT01624558 Effectiveness of Carbon Filters to Reduce the Anesthetic Gas Concentration in an Anesthetized Patient No drug interventions treatment Not Available withdrawn NCT05036148 Malignant Hyperthermia in Czech Republic: Description of the Biggest Slavonic Group of Patients Investigated for Risk of Malignant Hyperthermia No drug interventions Not Available Not Available completed NCT02561598 A Case Control Study of Patients With Diagnosis of Malignant Hyperthermia No drug interventions Not Available Not Available withdrawn NCT05402839 Screening of Malignant Hyperthermia Susceptible Individuals No drug interventions Not Available Not Available recruiting NCT04474860 Gene Mutation Spectrum of Malignant Hyperthermia in China No drug interventions Not Available Not Available unknown_status NCT02964481 Malignant Hyperthermia Registry and Genetic Testing No drug interventions Not Available Not Available terminated NCT04287556 Population at Risk of Malignant Hyperthermia: Ambispective Cohort. No drug interventions Not Available Not Available recruiting