Hypoparathyroidism (DBCOND0009079)

Identifiers

Synonyms
Parathyroid; Deficiency / Parathyroid deficiency / Hypoparathyroidism, unspecified / Hypoparathyroidism (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Calcitriol
An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
Calcium gluconate
An ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning.
No drug targets
Cholecalciferol
A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease.
Dihydrotachysterol
A synthetic analog of vitamin D that does not require renal activation like vitamin D2 or Vitamin D3.
Ergocalciferol
A vitamin found in many supplement products.
Palopegteriparatide
A parathyroid hormone analog used to treat hyperparathyroidism in adults.
Parathyroid hormone
An analog of human parathyroid hormone (PTH) used to treat hypocalcemia caused by hypoparathyroidism.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03910049
Does Indocyanine Imaging Scoring Predicts Postoperative Parathormone Levels at 24 Hours After Total ThyroidectomyNot AvailableNot Availablecompleted
NCT03309384
Intraoperative Monitoring to Predict Postoperative Complications After ThyroidectomyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05965167
Assess Safety and Compare PK of New Oral HPTH(1-34) Tablet Formulations Vs. EBP05 Tablets and Subcutaneous Forteotreatment1 / 2active_not_recruiting
NCT06419270
Cardiovascular, Renal, and Skeletal Complications in Patients With Post-Surgical HypoparathyroidismNo drug interventionsNot AvailableNot Availablerecruiting
NCT06531941
Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With Hypoparathyroidismtreatment2not_yet_recruiting
NCT06579430
Diagnostic Accuracy Study of Indocyanine Green for Perfusion Assessmentdiagnostic0completed
NCT04701203
A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidismtreatment3active_not_recruiting
NCT06288490
A Single Arm Study Comparing ACC Supplement to CCS in Management of HypoparathyroidismNo drug interventionstreatmentNot Availableterminated
NCT01815021
A Study Comparing Amorphous Calcium Carbonate (ACC) Versus Crystalline Calcium CCS) in Hypoparathyroidism PatientsNo drug interventionstreatment1 / 2completed
NCT05043584
Near-infrared Autofluorescence (NIRAF)-Guided Total Thyroidectomy: Impact in Low-volume, Non-parathyroid InstitutionsNo drug interventionspreventionNot Availablecompleted
NCT04053647
Quality of Life Evaluation (SF-36) in Patients With Permanent Hypoparathyroidism After Total Thyroidectomy (Qol-Hypopara)No drug interventionsNot AvailableNot Availablecompleted
NCT01268098
Study of Safety and Efficacy of a rhPTH[1-84] of Fixed Doses of 25 and 50 mcg in Adults With Hypoparathyroidism (RELAY)treatment3completed
NCT04126941
Monocentric Study on the Use of Teriparatide in Children With hypoparathyroïdismNo drug interventionsNot AvailableNot Availableunknown_status
NCT00824226
Magnesium Treatment in HypoparathyroidismNo drug interventionstreatmentNot Availablecompleted
NCT03516773
Oral PTH(1-34) PK and PD Study in Patients With Hypoparathyroidismtreatment2completed
NCT04009291
A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidismtreatment2active_not_recruiting
NCT05114980
Parathyroid Allotransplantation in Medically Refractory HypoparathyroidismNo drug interventionstreatmentNot Availablerecruiting
NCT00793689
Perioperative Parathormone Measurement and Sodium Bicarbonate Infusion Test After Total ThyroidectomyNo drug interventionsNot AvailableNot Availablecompleted
NCT02781844
Study to Assess the Blood Concentrations and Actions of Recombinant Human Parathyroid Hormone (rhPTH [1-84]) When Given Once and Twice Daily to Participants With Hypoparathyroidismtreatment1completed
NCT01922440
A Registry for Participants With Chronic HypoparathyroidismNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00856401
ADD-ON Study to Existing Hypoparathyroidism Studiesdiagnostic3unknown_status
NCT00001304
Treatment of Hypoparathyroidism With Synthetic Human Parathyroid Hormone 1-34treatment2completed
NCT04569604
QoL and Cognitive Function in Patients With HypoparathyroidismNo drug interventionsNot AvailableNot Availablecompleted
NCT00356512
Physiologic Regulation of FGF-23No drug interventionsNot AvailableNot Availablecompleted
NCT01039714
Vitamin D Levels and Postoperative Hypocalcemia After Total ThyroidectomyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01199614
HEXT (Hypo EXTended): Effect of PTH on Skeleton in Hypoparathyroidismtreatment3completed
NCT03150108
Study of rhPTH(1-84) in Japanese Healthy Subjects Compared With Matched Caucasian Healthy Adult Subjectstreatment1completed
NCT00395538
Effects of PTH Replacement on Bone in Hypoparathyroidismtreatment3terminated
NCT03364738
Safety and Efficacy Study of rhPTH(1-84) in Subjects With Hypoparathyroidismtreatment3terminated
NCT04209179
A Clinical Study Investigating the Safety, Tolerability, PK and PD of PCO371 in Patients With Hypoparathyroidismtreatment1terminated
NCT06547151
Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in Adultstreatment2not_yet_recruiting
NCT03514251
Study on Application of Suturing Parathyroid Markers in Thyroid Cancer SurgeryNo drug interventionspreventionNot Availableunknown_status
NCT05793853
Hypoparathyroidism Natural HistoryNo drug interventionsNot AvailableNot Availablerecruiting
NCT00004361
Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac DefectsNot AvailableNot Availablecompleted
NCT02152228
A Pilot Study to Assess the Safety and Efficacy of Oral PTH (1-34) in the Treatment of Hypoparathyroidismtreatment2completed
NCT00581828
Does Treatment of Hypovitaminosis D Increase Calcium Absorption?treatment4completed
NCT00566488
Parathyroid and Thymus Transplantation in DiGeorge #931No drug interventionstreatment1completed
NCT02986607
Corticosteroid Rhythms in Hypoparathyroid PatientsNo drug interventionsbasic_science0unknown_status
NCT01297309
A Open-label Study Investigating the Safety and Tolerability of NPSP558, a Recombinant Human Parathyroid Hormone (rhPTH [1-84]), for the Treatment of Adults With Hypoparathyroidism - A Clinical Extension Study (RACE)treatment3completed
NCT00732615
Use of NPSP558 in the Treatment of Hypoparathyroidismtreatment3completed
NCT02924532
Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total ThyroidectomyNot AvailableNot Availablecompleted
NCT03728959
Effects of a Liquid Meal and Gut Hormones (GIP and GLP-2) on Bone Remodeling in Participants With Hypoparathyroidism.No drug interventionsbasic_scienceNot Availablecompleted
NCT05387070
PaTHway CHINA TRIAL: A Trial to Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidismtreatment3recruiting
NCT06445036
Tunisian Clinical Registry on Hypoparathyroidism and Pseudo-hypoparathyroidismNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04671719
Determination of Circulating Autotaxin in Patients With GNAS or PTH AbnormalitiesNo drug interventionsNot AvailableNot Availablecompleted
NCT01498341
Hypoparathyroidism in DenmarkNo drug interventionsNot AvailableNot Availablecompleted
NCT04372225
Predicting Risk Factors of Postoperative Hypocalcemia After Total ThyroidectomyNo drug interventionsNot AvailableNot Availablecompleted
NCT02910466
A Study of Extended Use of Recombinant Human Parathyroid Hormone (rhPTH(1-84)) in Hypoparathyroidismtreatment4completed
NCT00473265
Bone Properties in Hypoparathyroidism: Effects of PTHtreatment2 / 3completed
NCT03437174
Burden of Illness in HypoparathyroidismNo drug interventionsNot AvailableNot Availablecompleted
NCT00743782
Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic Hypoparathyroidismtreatment0completed
NCT02838927
Survey on Epidemiology of Hypoparathyroidism in FranceNo drug interventionsNot AvailableNot Availablerecruiting
NCT05328076
Parathyroid Vascularization During Total Thyroidectomy Using Indocyanine Green AngiographyNot AvailableNot Availableterminated
NCT04750460
Injection of Teriparatide to Prevent Hypocalcemia After Parathyroidectomy in Dialysis Patients (TeriCa).treatment3completed
NCT04059380
Evaluation of iMmune Function in Post-surgical and AuToimmune HYpoparathyroidism (EMPATHY)No drug interventionsNot AvailableNot Availablecompleted
NCT03324880
A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE)treatment4completed
NCT06449729
Endocrine Determinants of Renal Function in Patients With HypoparathyroidismNo drug interventionsNot AvailableNot Availablecompleted
NCT03747029
Serum Calcium to Phosphorous (Ca/P) Ratio in the Diagnosis of Ca-P Metabolism Disorders: a Multicentre StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT05556629
A Survey to Assess Participants' and Physicians' Knowledge, Attitudes and Behavior When Using NATPARANo drug interventionsNot AvailableNot Availablerecruiting
NCT05684029
Near-Infrared Autofluorescence With PTH Test Strip as an SOP of Parathyroid in Thyroid SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT05022667
Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Total ThyroidectomyNo drug interventionspreventionNot Availablerecruiting
NCT05654701
Expanded Access Program of Palopegteriparatide in Patients With HypoparathyroidismNot AvailableNot Availableavailable
NCT00730210
Treatment of Hypoparathyroidism With Subcutaneous PTH (1-84) Injections: Effects on Muscle Function and Quality of Lifetreatment2completed
NCT01455181
A Study to Investigate the Safety and Tolerability of NPSP558, for the Treatment of Adults With Hypoparathyroidism - A Clinical Extension Study in Hungarytreatment3completed
NCT06465108
Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidismtreatment2recruiting
NCT04465227
Safety, Tolerability, Pharmacodynamics and Pharmacokinetics, and Efficacy of CLTX-305 in Autosomal Dominant Hypocalcemia Type 1 (ADH1)No drug interventionstreatment2not_yet_recruiting