Gonorrhea (DBCOND0020780)

Identifiers

Synonyms
Neisseria Gonorrhoeae Infection / Gonorrhoeae / Gonorrhoea / Gonococcal infection, unspecified / Gonococcal infection / Gonorrhoea NOS / Gonorrhea (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Cefotetan
An antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections.
Cefpodoxime
A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis.
Cefuroxime
A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo.
Clavulanic acid
A beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
Gemifloxacin
A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.
Sulfamethizole
A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.
Tetracycline
An antibiotic used to treat a wide variety of susceptible infections.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01329588
Periodical Presumptive Treatment for the Control of Gonococcal Infections Among Sex Workerstreatment4completed
NCT04269434
GonoScreen: Efficacy of Screening STIs in MSMNo drug interventionsscreeningNot Availablecompleted
NCT00978848
Non-Invasive Sexually Transmitted Disease Testing in Women Seeking Emergency Contraception or Urine Pregnancy TestingNo drug interventionsNot AvailableNot Availablecompleted
NCT06369220
A Study of the Cobas® Liat CT/NG/MG Test Versus Current Standard Practice for Managing Participants at Increased Risk of Sexually Transmitted InfectionsNo drug interventionsdiagnosticNot Availablerecruiting
NCT02870101
Performance of Nucleic Acid Amplification Tests for the Detection of NG and CTNo drug interventionsotherNot Availablecompleted
NCT01733069
Clinical Evaluation of the APTIMA® COMBO 2® Assay Using the PANTHER™ SystemNo drug interventionsNot AvailableNot Availablecompleted
NCT05971550
Clearance of Asymptomatic Pharyngeal Carriage of Neisseria Gonorrhoeae With or Without Ceftriaxone Treatment: Randomized Non-inferiority Studyother3not_yet_recruiting
NCT04094883
Study to Assess Gonorrhoeae Immune Responses Induced by a N. Meningitidis Vaccinetreatment4completed
NCT05286931
SpeeDx Ciprofloxacin gyrA Assay for N. Gonorrhoeae Gonococcal InfectionotherNot Availablerecruiting
NCT05581160
Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST)No drug interventionsdiagnosticNot Availablerecruiting
NCT05216744
Comparison of Efficacy of Two Combination Regimens for the Neisseria Gonorrhoeae and Chlamydia Coinfectiontreatment2completed
NCT01439503
Safer Sex Program for Young African-American MenNo drug interventionsprevention2completed
NCT01665690
Washington State Community Expedited Partner Treatment (EPT) TrialNo drug interventionsprevention4completed
NCT06187064
Combination Primary Care and Prevention Services for Women Who Inject Drugs and Exchange Sex in Seattle, WashingtonNo drug interventionshealth_services_researchNot Availablerecruiting
NCT02391233
Multimedia WORTH With Black Drug-Involved Women on ProbationNo drug interventionspreventionNot Availablecompleted
NCT06352554
Susceptibility Testing In Neisseria Gonorrhoeae (STING) Study, Assessing the Performance of a New Rapid Test for Gonorrhoea Antibiotic Resistance, in a Cohort of 100 Culture Positive Neisseria Gonorrhoeae InfectionsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05873751
A Study to Learn About How Trumenba Vaccine Shots Work Against Gonorrhea Infection in Teenagers and Young Adults in the United States.Not AvailableNot Availablecompleted
NCT02019771
Gonorrhea and Chlamydia HIV-infected Men Who Have Sex With MenNo drug interventionsNot AvailableNot Availablecompleted
NCT04966507
Antibacterial Mouthwash for Pharyngeal Gonorrhea Preventionprevention2recruiting
NCT01465607
Implementation of an Efficacious Intervention for High Risk Women in MexicoNo drug interventionshealth_services_researchNot Availablecompleted
NCT02015637
Comparison of Delafloxacin Versus Ceftriaxone for the Treatment of Uncomplicated Gonorrheatreatment3terminated
NCT01638637
Prospective Collection of Female and Male Specimens for PANTHER® System TestingNo drug interventionsNot AvailableNot Availablecompleted
NCT06188442
Superiority of On-demand PrEP Versus PEP on Using Doxycycline for Preventing STI in MSMprevention4not_yet_recruiting
NCT04268342
Gonorrhoea Resistance Assessment by Nucleic Acid Detection (GRANDII)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT00207506
Lay Health Advisors for Sexually Transmitted Disease PreventionNo drug interventionsprevention1 / 2completed
NCT04297436
Gonococcal Vaccine Study in Key Populations in Kenyabasic_scienceNot Availablecompleted
NCT04955717
Antenatal Chlamydia Trachomatis and Neisseria Gonorrhoeae Testing to Prevent Adverse Neonatal ConsequencesNo drug interventionsscreeningNot Availablecompleted
NCT03186534
Randomized Trial of an HIV Prevention and Relationship Education Program for Young Male CouplesNo drug interventionsprevention2completed
NCT03715335
Adolescent Sexually Transmitted Infection Screening in the Emergency DepartmentNo drug interventionsscreeningNot Availableactive_not_recruiting
NCT05723263
Pay-it-forward Gonorrhea and Chlamydia Testing Among Men in ChinaNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT06154239
Screening With Tampons: Evaluating Diagnostic Accuracy and HPV and Assessing Participant ViewsNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT04010539
A Study Evaluating Efficacy and Safety of Gepotidacin Compared With Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrheatreatment3completed
NCT05613725
OptiGon - Optimising Laboratory Assays for Immune Responses to GonococcusNo drug interventionsNot AvailableNot Availablecompleted
NCT02513225
Trial of an Adapted STD Screening and Risk Reduction InterventionNo drug interventionspreventionNot Availablecompleted
NCT01184157
Randomized Trial of Home Versus Clinic-based Screening for Sexually Transmitted InfectionsNo drug interventionsscreeningNot Availablecompleted
NCT06090565
Cefixime Plus Doxycycline Compared to Ceftriaxone Plus Azithromycin for Treatment of Gonorrhoeatreatment4completed
NCT02294682
A Dose-Ranging Study Evaluating the Efficacy, Safety, and Tolerability of GSK2140944 in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria Gonorrhoeaetreatment2completed
NCT03896776
A Pragmatic Trial of Two Strategies for Implementing an Effective eHealth HIV Prevention Program (Keep It Up! 3.0)No drug interventionspreventionNot Availablecompleted
NCT03098329
Check it: A New Approach to Controlling Chlamydia Transmission in Young PeopleNo drug interventionsscreeningNot Availablecompleted
NCT05766904
Efficacy Trial on Meningococcal B Vaccine for Preventing Gonorrhea Infectionsprevention3recruiting
NCT03980223
Evaluation of Doxycycline Post-exposure Prophylaxis to Reduce Sexually Transmitted Infections in PrEP Users and HIV-infected Men Who Have Sex With Menprevention4completed
NCT01728103
Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) AssaysNo drug interventionsNot AvailableNot Availableterminated
NCT00187902
Evaluation of NAATs for Detection of C. Trachomatis and N. Gonorrhoeae From Pharynx, Rectum, Glans & Urethra of MSMNo drug interventionsNot AvailableNot Availablecompleted
NCT03090802
MAMAS: Mentoring Adolescent Mothers at SchoolNo drug interventionspreventionNot Availablecompleted
NCT02447484
Texting Intervention to Sustain HIV Prevention in Women in High-drug-use ContextsNo drug interventionspreventionNot Availablecompleted
NCT05727033
Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted InfectionsNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT01720654
Expedited Partner Therapy for MSM in PeruNo drug interventionspreventionNot Availablecompleted
NCT06566677
Point of Care Rapid STI Test Optimization and Validation ExtensionNo drug interventionsNot AvailableNot Availablecompleted
NCT01167777
Multi-center Evaluation of the VERSANT® CT/GC DNA 1.0 Assay (kPCR)in Detecting C. Trachomatis and N. GonorrhoeaeNo drug interventionsNot AvailableNot Availableterminated
NCT01836445
Keep It Up! 2.0: A Comparison of Two Online HIV Intervention Programs for Young Men Who Have Sex With MenNo drug interventionspreventionNot Availablecompleted
NCT05870098
Meatal Swab Yourself With Testing for Infections CollectivelyNo drug interventionsdiagnosticNot Availablerecruiting
NCT00827697
A Validation Study for Detecting Chlamydia and Gonorrhea in Rectal SamplesNo drug interventionsNot AvailableNot Availablecompleted
NCT05326061
Vienna HIV Infection Via Sex StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00124878
Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the CommunityNo drug interventionsprevention3unknown_status
NCT05678556
Effectiveness of Relationship Education for Reducing HIV Incidence Among SGMNo drug interventionspreventionNot Availablerecruiting
NCT00177437
Home Screening for Chlamydia SurveillanceNo drug interventionsprevention3completed
NCT06446752
BIYELA - Bexsero Immunisation in Young Women in Africaprevention3not_yet_recruiting
NCT02795975
Clinical Evaluation of the Aptima® Combo 2® Assay Using the Panther® System in Female Urine SamplesNo drug interventionsNot AvailableNot Availableterminated
NCT00120770
Cellulose Sulfate (CS) Gel and HIV in NigeriaNo drug interventionsprevention3terminated
NCT02055742
Detection of Chlamydia (CT) and Gonorrhea (NG)No drug interventionsNot AvailableNot Availablecompleted
NCT03718806
Study to Investigate Effect of Food and Safety of a New Formulation of Zoliflodacintreatment1completed
NCT00262106
Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infectionprevention3completed
NCT04398849
Immunisation for Adolescents Against Serious Communicable Diseases (B Part of it NT)No drug interventionsNot AvailableNot Availablerecruiting
NCT03284541
Online HIV Prevention for Young Male CouplesNo drug interventionsprevention2completed
NCT01708317
Computer-Assisted Self-Interviews and Health Screening in the Pediatric Emergency DepartmentNo drug interventionsscreeningNot Availablecompleted
NCT03867734
Aztreonam for Pharyngeal Gonorrheatreatment2 / 3completed
NCT00252096
Nucleic Acid Amplification Tests (NAATs) for the Diagnosis of Pharyngeal and Rectal Chlamydia and Gonorrhea InfectionsNo drug interventionsdiagnosticNot Availablecompleted
NCT00692822
Antimicrobial Susceptibility Patterns of N. Gonorrhea Isolates in an Era of Quinolone ResistanceNo drug interventionsNot AvailableNot Availablecompleted
NCT01195220
Project AWARE: Using the Emergency Department (ED) to Prevent Sexually Transmitted Infections (STIs) in YouthNo drug interventionspreventionNot Availablewithdrawn
NCT03895320
Protecting Our Future Generation: Promotion of Protective Sexual Health Practices Among Native American Youth and Young Adults Through an Assets-based Self-care InterventionNo drug interventionsbasic_scienceNot Availablecompleted
NCT03959527
Zoliflodacin in Uncomplicated Gonorrhoeatreatment3completed
NCT04902560
Response Rate to Ceftriaxone 1g IM in Gonorrhoea : a French Retrospective Monocentric StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02099760
Cepheid Rectal Sample Validation StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02122094
Implementation of a Sexual Health Intervention for Young Men Who Have Sex With Men (MSM) in Two Vietnamese CitiesNo drug interventionstreatmentNot Availablecompleted
NCT01654991
Randomized Trial of Home Versus Clinic-Based STD TestingNo drug interventionsscreeningNot Availablecompleted
NCT00381992
Risk Assessment of Long-Haul Truck DriversNo drug interventionsNot AvailableNot Availablecompleted
NCT04484740
Penetration of the Innovative Antibiotic Gepotidacin Into Prostate and Tonsillar Tissuetreatment1completed
NCT04553068
Evaluation of EVO100 for Prevention of Urogenital Chlamydia Trachomatis and Neisseria Gonorrhoeae InfectionNo drug interventionsprevention3completed
NCT04202068
A Study Evaluating Efficacy and Safety of CRO-SBT in the Treatment of Gonorrheatreatment4completed
NCT03071510
Evaluation of the Atlas Genetics io® CTNG SystemNo drug interventionsNot AvailableNot Availablecompleted
NCT05541081
Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in ZimbabweNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT03294395
New AntiBiotic Treatment Options for Uncomplicated Anogenital GOnorrhoeatreatment3completed
NCT04325555
Pre-exposure Prophylaxis: A Miracle Drug or a Moral HazardNo drug interventionsNot AvailableNot Availablecompleted
NCT06100250
Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection ScreeningNo drug interventionshealth_services_researchNot Availablerecruiting
NCT00644150
Effectiveness of HIV/Sexually Transmitted Infection Training for Physicians in ChinaNo drug interventionspreventionNot Availablecompleted
NCT06428643
A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis DisparitiesNo drug interventionsscreeningNot Availablenot_yet_recruiting
NCT04722003
Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB VaccinationNo drug interventionsprevention2completed
NCT03596151
Clinical Study of a Single-Use, Point-of-Care Molecular Diagnostic Device for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) Utilizing Vaginal SwabsNo drug interventionsdiagnosticNot Availableterminated
NCT02350907
Rapid Diagnosis of Antibiotic Resistance in GonorrhoeaNo drug interventionsNot AvailableNot Availablecompleted
NCT02257918
Randomized, Open-label Phase 2 Study of Oral AZD0914 in the Treatment of Gonorrheatreatment2completed
NCT00926796
Efficacy of Combination Therapies for Gonorrhea Treatmenttreatment4completed
NCT02708992
Cefixime / Azithromycin pK Studytreatment1completed
NCT03404167
A Study to Evaluate the Safety, Tolerability and Plasma PK of a Single Oral Dose of Zoliflodacin in Healthy Male and Female Volunteerstreatment1completed
NCT02348424
Genitourinary and Pharyngeal Pharmacokinetics of Solithromycintreatment1completed
NCT01949363
The Pharmacokinetics of Extended Duration High-dose Cefixime for the Decreased Susceptibility of Neisseria Gonorrhoeae: A Phase I Pilot Studytreatment1completed