NCT00772603
Evaluation of Efficacy and Safety of OXC XR as Adjunctive Therapy for Partial Seizures treatment 3 completed NCT03446664
Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study No drug interventions treatment Not Available completed NCT06534502
Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset Seizures treatment 4 not_yet_recruiting NCT00151879
Safety and Tolerability of Intravenous SPM 927 as Replacement for Oral SPM 927 in Subjects With Partial Seizures treatment 2 / 3 completed NCT03882151
Added Value of Automated Electrical Source Localization (EPILOG PreOp®) to Presurgical Evaluation of Refractory Epilepsy No drug interventions diagnostic Not Available unknown_status NCT00918047
Study of PK and Safety of OXC (Oxcarbazepine) XR (Extended Release) as Adjunctive Therapy in Pediatric Epilepsy Patients treatment 1 completed NCT00212745
Pilot Trial of a Behavioral Treatment for Epilepsy No drug interventions treatment 1 / 2 completed NCT00230698
A Study of the Effectiveness and Safety of Topiramate Monotherapy in Patients With Recently Diagnosed Partial-Onset Seizure treatment 3 completed NCT00351611
Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo treatment 4 completed NCT00215215
Effectiveness Study Comparing Treatment With Drug(s) or Adjunctive VNS Therapy for Pharmacoresistant Partial Seizures No drug interventions treatment 4 terminated NCT00643136
A Study of Lyrica as Treatment for Sleep Problems in Patients With Sleep Problems and Seizures treatment 3 completed NCT00072813
MRI in Autosomal Dominant Partial Epilepsy With Auditory Features No drug interventions Not Available Not Available completed NCT00512317
Open-label Extension to Protocol 1042-0600 treatment 2 completed NCT00280696
A Double-blind Confirmatory Trial of Levetiracetam in Epilepsy Patients With Partial Onset Seizures treatment 3 completed NCT00236886
Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy Patients treatment 3 completed NCT00524030
Efficacy And Safety Study Of Pregabalin (Lyrica) As Monotherapy In Patients With Partial Seizures treatment 3 terminated NCT00236730
A Study of the Efficacy and Safety of Topiramate in the Treatment of Patients With Difficult to Control Epilepsy treatment 2 completed NCT00991757
An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures. treatment 3 completed NCT06550726
High-resolution Multi-parametric Magnetic Resonance Imaging for Focal Epilepsy No drug interventions diagnostic Not Available not_yet_recruiting NCT03559673
Compassionate Use Program With Lacosamide in Patients With Partial-onset or Generalized Tonic-clonic Seizures Not Available Not Available no_longer_available NCT00771927
Post-Authorization Safety Study to Assess the Safety of Vimpat as add-on Therapy in Patients With Partial-onset Seizures Not Available Not Available completed NCT00236691
A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures. treatment 2 completed NCT00537940
Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures treatment 4 completed NCT00319501
Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures. treatment 3 completed NCT01441401
Safety and Efficacy of Gabapen for Pediatric (Regulatory Post Marketing Commitment Plan) Not Available Not Available completed NCT00567268
Drug Use Investigation Of Gabapentin Not Available Not Available completed NCT05015868
Contribution of Genetics, Non-invasive Methods and Neuropsychology in Focal Cryptogenic Epilepsies No drug interventions diagnostic Not Available recruiting NCT05248269
Thermocoagulation in Drug Resistant Focal Epilepsy No drug interventions treatment Not Available active_not_recruiting NCT04309812
Transcranial Direct Current to Treat Epilepsy at Home No drug interventions treatment 0 enrolling_by_invitation NCT00422110
A Study to Evaluate the Efficacy and Safety of Seletracetam in Adult Patients With Refractory Partial Onset Seizures treatment 2 / 3 withdrawn NCT00236743
A Study of the Effectiveness and Safety of Topiramate in the Treatment of Children With Epilepsy treatment 3 completed NCT02635633
Continuous Thetaburst Stimulation for the Treatment of Refractory Epilepsy - Safety, Feasibility and Proof-of-concept No drug interventions treatment Not Available terminated NCT01262677
Once-A-Day Pregabalin For Partial Seizures treatment 3 completed NCT00236847
A Study of the Efficacy and Safety of Topiramate in the Treatment of Patients With Epilepsy. treatment 2 completed NCT01663545
Brain P-gp and Inflammation in People With Epilepsy No drug interventions Not Available Not Available completed NCT05273398
Effects of Diazepam on RNS Detections diagnostic 4 completed NCT03054961
Cerebral Oxygen Saturation and Cytochrome Oxidase REDOX State in Children With Epilepsy: A Pilot Study No drug interventions Not Available Not Available completed NCT03949478
Treating Postictal Symptoms Using Ibuprofen and Nifedipine treatment 2 recruiting NCT00231556
A Study on Safety and Efficacy of Two Doses of Topiramate as Monotherapy in the Treatment of Newly Diagnosed or Recurrent Epilepsy treatment 3 completed NCT01745952
Treatment of Difficult to Control Focal Epilepsy With Repetitive Transcranial Magnetic Stimulation (rTMS) No drug interventions treatment Not Available completed NCT00210652
An Open-Label Extension Study to Evaluate the Safety and Effectiveness of RWJ 333369 in Patients With Epilepsy No drug interventions treatment 2 completed NCT00050934
Pediatric Epilepsy Study treatment 3 completed NCT00448916
Open-Label Extension Study Of Safety And Tolerability Of Pregabalin In Pediatric Patients With Partial-Onset Seizures treatment 3 completed NCT00210522
An Open-Label Extension Study of the Effectiveness and Safety of the Investigational Compound RWJ-333369 in Patients With Epilepsy No drug interventions treatment 2 completed NCT03916848
Novel Network Analysis of Intracranial Stereoelectroencephalography No drug interventions basic_science Not Available unknown_status NCT06374966
Real-world Study of Efficacy and Safety of Zonisamide in add-on Therapy for Patients With Focal Epilepsy Not Available Not Available not_yet_recruiting NCT00236873
A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures. treatment 2 completed NCT00603473
A Phase III Open-Label Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures treatment 3 completed NCT00236860
A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures treatment 2 completed NCT01098162
Vimpat® Added as Adjunctive Therapy to One Baseline Antiepileptic Drug No drug interventions Not Available Not Available completed NCT00266604
A Study to Evaluate the Dosing, Effectiveness and Safety of Topiramate for the Treatment of Epilepsy treatment 4 completed NCT03200769
Study of the Efficacy of the Treatment of Sleep Apnea Syndrome by CPAP in Pharmacoresistant Epilepsy No drug interventions treatment Not Available completed NCT00437281
Safety, Tolerability, and Pharmacokinetic Study of Pregabalin in Pediatric Patients With Partial Onset Seizures treatment 1 / 2 completed NCT03689114
Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW) treatment 4 active_not_recruiting NCT00620555
A Phase III Open-Label Extension Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures treatment 3 completed NCT00143143
Pregabalin Open-Label Extension Trial in Patients With Partial Seizures treatment 3 completed NCT04383028
MELD as an Adjunct for SEEG Trajectories No drug interventions diagnostic Not Available unknown_status NCT00425282
A Study of the Efficacy and Safety of RWJ-333369 as add-on Therapy in the Treatment of Partial Onset Seizures. No drug interventions treatment 3 completed NCT00175929
A Study of Brivaracetam in Subjects With Partial Onset Seizures treatment 2 completed NCT00433667
A Study of the Efficacy and Safety of RWJ-333369 as add-on Therapy in the Treatment of Partial Onset Seizures. No drug interventions treatment 3 completed NCT04061707
Subcutaneous EEG: Forecasting of Epileptic Seizures No drug interventions Not Available Not Available completed NCT05198882
Clinical Evaluation of Interstitial Laser Thermal Therapy Under Continuous MRI Monitoring as a Minimally Invasive Treatment of Patients With Medically Unbalanced Partial Epilepsy No drug interventions treatment 1 unknown_status NCT03268824
Impact of Epileptic Discharge on the Structural Connectivity of the Developing Brain No drug interventions Not Available Not Available recruiting NCT00175890
A Placebo-controlled Study of Levetiracetam In Children (1mo to 4yrs of Age) With Partial Onset Seizures. treatment 3 completed NCT00160654
Open Label Safety and Efficacy Study of Levetiracetam in Patients With Epilepsy treatment 4 completed NCT00152451
Study With Seletracetam (Ucb 44212) in Adult Subjects (18 to 65 Years) With Partial Onset Seizures treatment 2 completed NCT00160628
Open Label Safety and Efficacy Study of Levetiracetam in Korean Patients With Epilepsy Not Available 3 completed NCT00160615
Follow-up Study of L059 (Levetiracetam) in Epileptic Patients With Partial Onset Seizures by Open Label Method treatment 3 completed NCT00280059
Study Of The Safety And Efficacy Of Lyrica In The Treatment Of Newly Diagnosed Partial Epilepsy treatment 3 completed NCT00245713
Determine Effects of Adjunctive Levetiracetam on Sleep Architecture in Adults With Partial Onset Epilepsy. Not Available 4 completed NCT00152516
Long-Term, Follow-Up Study Of the Safety And Efficacy Of Levetiracetam In Children With Partial Onset Seizures treatment 3 completed NCT01332539
An Observational Study to Assess the Burden of Drug-resistant Partial Epilepsy in Italy No drug interventions Not Available Not Available completed NCT01375374
Hormonal and Lipid Levels in Male Subjects After a Switch From Carbamazepine to Lacosamide treatment 3 terminated NCT00105040
A 19-week Cognition Study of Levetiracetam in Children With Partial Onset Seizures treatment 2 completed NCT01691872
Pharmacokinetic Study of Retigabine Extended Release (XR) Formulation in Healthy Adult Japanese and Caucasian Subjects other 1 withdrawn NCT02220972
To Evaluate the Effect of Perampanel on Objective and Subjective Sleep in Subjects With Insomnia and Partial Onset Seizures treatment 4 withdrawn NCT00152503
Study With Subjects 18-65 Years Old With Partial Onset Seizures Who Are Currently Taking Levetiracetam treatment 2 completed NCT01891890
Cognitive AED Outcomes in Pediatric Localization Related Epilepsy (COPE) treatment 3 terminated NCT00150709
A Study Of The Safety And Efficacy Of Levetiracetam (Keppra®) (Ucb L059) In Children With Epilepsy treatment 3 completed NCT00643500
Pharmacovigilance Study of Keppra. SPAIN - SKATE : Safety of Keppra as Adjunctive Therapy in Epilepsy treatment 4 completed NCT01545518
IVIG Treatment for Refractory Immune-Related Adult Epilepsy No drug interventions treatment 2 terminated NCT00113165
Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Partial Seizures treatment 3 completed NCT00355082
Conversion To Monotherapy With Lamictal Extended Release Tablets For Treatment Of Partial Epilepsy treatment 3 completed NCT00152373
Double-blind, Placebo-controlled Study of Levetiracetam in Adults With POS Not Available 3 completed NCT01457989
Meta-Analysis Plan for Pooled Data for Studies VRX-RET-E22-303 and VRX-RET-E22-304 Not Available Not Available completed NCT00141414
To Evaluate the Long-Term Safety of Pregabalin in Refractory Partial Epilepsy. treatment 2 completed NCT00552305
To Determine Tolerability and Efficacy of Long-term Oral Lacosamide in Patients With Partial Seizures treatment 2 completed NCT00655486
Study to Assess the Long-term Safety of Oral Lacosamide in Subjects With Partial-onset Seizures treatment 3 completed NCT01235403
Trial to Assess Optimized Dosage of Lacosamide as add-on Therapy in Patients With Partial Onset Seizure treatment 4 completed NCT00655551
Safety of Intravenous Lacosamide Dose Followed by Twice Daily Oral Lacosamide in Subjects With Partial-onset Seizures treatment 3 completed NCT00522275
Determine Safety and Efficacy of Long-term Oral Lacosamide in Patients With Partial Seizures treatment 3 completed NCT00955357
Trial to Assess Lacosamide as the First add-on Anti-epileptic Drug Treatment in Patients With Partial-onset Seizures treatment 4 completed NCT00982787
Safety and Anticonvulsant Efficacy of Passiflora Incarnata Extract in Patients With Partial Epilepsy No drug interventions treatment 2 withdrawn NCT02076698
Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Epilepsy No drug interventions treatment 3 completed NCT01866111
A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures treatment 2 completed NCT01281956
PRX-00023 Therapy in Localization-Related Epilepsy treatment 2 terminated NCT00900237
Study to Evaluate Pharmacokinetics and Tolerability of Multiple Doses of Eslicarbazepine Acetate and Oxcarbazepine treatment 1 completed NCT03478852
Investigating Epilepsy: Screening and Evaluation No drug interventions Not Available Not Available recruiting NCT01527513
Effects of Eslicarbazepine Acetate (Esl, Bia 2-093) on Cognitive Function in Children With Partial Onset Seizures treatment 2 completed NCT00391534
EXTENT: EXtended Tolerability and Efficacy of a Novel Formulation of Oxcarbazepine in a Trial in Partial Epilepsy treatment 3 terminated NCT01090934
Localizing the Epileptogenic Zone With High Resolution Electroencephalography No drug interventions diagnostic Not Available completed NCT00001325
Metabolic Abnormalities in Children With Epilepsy No drug interventions Not Available Not Available completed NCT00001666
Transcranial Magnetic Stimulation for the Treatment of Poorly Controlled Partial Epilepsy No drug interventions Not Available Not Available completed NCT00898560
Effect of Repeat Administration of Eslicarbazepine Acetate on the Pharmacokinetics of a Combined Oral Contraceptive treatment 1 completed NCT00706160
Language Mapping in Patients With Epilepsy No drug interventions Not Available Not Available completed NCT04513860
Cenobamate Expanded Access Program (EAP) Not Available Not Available approved_for_marketing NCT00957372
Efficacy and Safety of Eslicarbazepine Acetate as Adjunctive Therapy for Refractory Partial Epilepsy treatment 3 completed NCT01397968
Efficacy and Safety of YKP3089 in Subjects With Treatment Resistant Partial Onset Seizures treatment 2 completed NCT04903314
Dose-Escalation Study of Cenobamate (YKP3089) in Pediatric Subjects With Partial-Onset Seizures treatment 1 recruiting NCT01373190
Thermographic Examination of Skin Temperatures in Individuals With Focal Onset Epilepsy No drug interventions Not Available Not Available completed NCT00957047
Efficacy and Safety Study of BIA 2-093 in Combination With Other Anti-Epileptic Drugs to Treat Partial Epilepsy treatment 3 completed NCT01190098
Randomized Controlled Trial to Assess Effects of Lacosamide on Sleep and Wake in Adults With Focal Epilepsy treatment 4 completed NCT00894478
Improving Lesion Detection in Children With Magnetic Resonance Imaging (MRI)-Negative Partial Epilepsy Using Diffusion Tensor Imaging No drug interventions Not Available Not Available completed NCT01735032
Multimodal Imaging in Pre-surgical Evaluation of Epilepsy No drug interventions Not Available Not Available unknown_status NCT00001932
Serotonin Receptors in Seizure Disorders No drug interventions Not Available Not Available completed NCT00908349
Safety and Tolerability of OXC XR as Adjunctive Therapy in Subjects With Refractory Partial Epilepsy treatment 3 completed NCT00522418
Study Comparing Best Medical Practice With or Without VNS Therapy in Pharmacoresistant Partial Epilepsy Patients No drug interventions treatment 4 terminated NCT00465517
A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures treatment 2 completed NCT05067634
Safety and Efficacy Study of Cenobamate in Pediatric Subjects 2-17 Years of Age With Partial-onset (Focal) Seizures treatment 3 recruiting NCT02535091
Safety and Pharmacokinetic Study of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures treatment 3 completed NCT01273129
Surgery as a Treatment for Medically Intractable Epilepsy No drug interventions Not Available Not Available recruiting NCT00988429
Efficacy and Safety of Eslicarbazepine Acetate (BIA 2-093) as Adjunctive Therapy for Refractory Partial Seizures treatment 3 completed NCT01496612
Buspirone Therapy for Localized Epilepsy treatment 2 terminated NCT01048255
Study of VX-765 in Subjects With Treatment-resistant Partial Epilepsy treatment 2 completed NCT04986683
Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery No drug interventions diagnostic Not Available recruiting NCT02245061
Cortical Excitability Assessment Using Paired Pulses No drug interventions diagnostic Not Available unknown_status NCT06132893
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy No drug interventions treatment 2 / 3 recruiting NCT06366009
Assessment of Patients With Drug-resistant Temporal Lobe Epilepsy With EEG Extended With Intra-auricular Electrodes No drug interventions Not Available Not Available not_yet_recruiting NCT05673915
Study of Transcranial Direct Current Stimulation to Treat Epilepsy No drug interventions treatment Not Available recruiting NCT03644732
Atlas of Human Cognition by SEEG (MAPCOG-SEEG) No drug interventions Not Available Not Available recruiting NCT05748236
The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal Epilepsy treatment 4 enrolling_by_invitation NCT01724918
Lacosamide IV and EEG/EKG (LIVE) Study treatment 2 terminated NCT05180916
Priming the Epileptic Brain: tVNS to Improve Efficacy of add-on AED in Patients With Focal Epilepsy No drug interventions treatment Not Available unknown_status NCT02898935
Improvement of the Accuracy of Spatial Representation of Invasive Exploratory Electrodes in Focal Epilepsy No drug interventions Not Available Not Available completed NCT03082222
ZEDEBAC: Zebinix Effects in Dependency of Baseline Conditions No drug interventions Not Available Not Available completed NCT06210022
Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy No drug interventions Not Available Not Available recruiting NCT06309966
Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy No drug interventions treatment 2 / 3 recruiting NCT03796962
A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy No drug interventions treatment 2 active_not_recruiting NCT03321240
Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia No drug interventions Not Available Not Available unknown_status NCT04839601
RNS System RESPONSE Study No drug interventions treatment Not Available recruiting NCT05981755
Breathing Rescue for SUDEP Prevention No drug interventions basic_science Not Available recruiting NCT05278221
TMS Combined With EEG/EMG as a Biomarker Predicting Antiepileptic Drug Response No drug interventions diagnostic Not Available recruiting NCT04879433
Prospective Open-label Evaluation of Cenobamate Adjunctive Treatment of Adults With Refractory Focal Epilepsy No drug interventions Not Available Not Available unknown_status NCT04529954
Anti-Epilepsy Medication Valproate Administered Via ICV Route and Catheters and Pumps for CSF Infusion treatment 1 / 2 terminated NCT01772654
Arterial Spin Labeling MRI Focal Abnormalities in Refractory Epilepsy No drug interventions diagnostic Not Available completed NCT03607851
Efficacy and Safety of Rapid Titration Protocols of Lacosamide treatment 4 completed NCT00438451
Study on the Treatment of Elderly Patients With Older and Newer Antiepileptic Drugs treatment 4 completed NCT05481905
ENACT: A Study of ENX-101 as Adjunctive Treatment in Patients With Focal Seizures No drug interventions treatment 2 withdrawn NCT03457961
Post-market Study of AMPA Receptor Antagonists for Epilepsy Patients in Hong Kong Not Available Not Available unknown_status NCT05497193
Clinical Efficacy and Safety of Perampanel Monotherapy in the Treatment of Children With Focal Epilepsy Not Available Not Available unknown_status NCT05100771
Optimized Volumetry in Radiology: Interest in Pediatric Brain MRI in the Exploration of Focal Epilepsy No drug interventions Not Available Not Available recruiting NCT03955432
Long-term Cardiac Monitoring in Epilepsy No drug interventions treatment Not Available terminated NCT06453759
Thalamic Recordings in Children Undergoing SEEG No drug interventions basic_science Not Available not_yet_recruiting NCT05081518
A Study of Lu AG06466 in Participants With Treatment Resistant Focal Epilepsy No drug interventions treatment 1 terminated NCT05718817
An Open-label Study of XEN1101 in Epilepsy No drug interventions treatment 3 enrolling_by_invitation NCT05635396
Seizures Detection in Real Life Setting No drug interventions other Not Available not_yet_recruiting NCT06443463
Long-term Safety and Tolerability of BHV-7000 No drug interventions treatment 2 enrolling_by_invitation NCT02126774
The Human Epilepsy Project No drug interventions Not Available Not Available completed NCT06205160
Evaluation of New Flexible High-density Intra-operative ECoG Electrodes for Epilepsy Surgery. ( EpiGrid ) No drug interventions diagnostic Not Available not_yet_recruiting NCT02208492
The Effects on Cognitive Function of Levetiracetam (Keppra®) Compared to Carbamazepine (Tegretol®, Carmazepine®) as Monotherapy for Children With Partial Seizure; A Multicentric Randomized Controlled Study treatment 4 completed NCT01311440
Modified Atkins Diet Treatment for Adults With Drug-resistant Epilepsy No drug interventions treatment Not Available completed NCT04653012
Multi-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic Patients No drug interventions basic_science Not Available not_yet_recruiting NCT03278210
National Study on the Interest of EEG-fMRI in the Presurgical Evaluation of Partial Epilepsies Drug No drug interventions Not Available Not Available unknown_status NCT04998123
Efficacy of Intersectional Short Pulse Stimulation for Terminating Seizures No drug interventions treatment Not Available not_yet_recruiting NCT00855738
A Prospective, Observational Study On The Effectiveness Of New Antiepileptic Drugs As First Bitherapy In The Daily Clinical Practice treatment 4 completed NCT00552045
Epilepsy Phenome/Genome Project No drug interventions Not Available Not Available completed