Postherpetic Neuralgia (DBCOND0029450)

Identifiers

Synonyms
Post-Herpetic Neuralgia / Post Herpetic Neuralgia (PHN) / Postherpetic Neuralgia (PHN) / Post-Herpetic Neuralgia (PHN) / Neuralgia, Postherpetic / PHN / Post herpetic neuralgia / Postherpetic neuralgia / Postherpetic neuralgia (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Botulinum toxin type A
A purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.
Capsaicin
A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
Clonidine
An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
Desipramine
A tricyclic antidepressant used in the treatment of depression.
Gabapentin
An anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures.
Gabapentin enacarbil
A gabapentin prodrug used to treat Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).
Lidocaine
A local anesthetic used in a wide variety of superficial and invasive procedures.
Methotrimeprazine
A phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
Methyl salicylate
A topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
Nortriptyline
A tricyclic antidepressant used in the treatment of depression.
Pregabalin
An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.
Triamcinolone
A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01748877
Efficacy, Tolerability, and Safety of NXN-462 in Patients With Post-Herpetic NeuralgiaNo drug interventionstreatment2completed
NCT05496205
A SAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy VolunteersNo drug interventionstreatment1completed
NCT03765697
A Study With Lidocaine 5% Medicated Plaster in Patients Suffering From Postherpetic Neuralgiatreatment3completed
NCT01270828
Safety And Efficacy Study Of Once Daily Controlled Release Pregabalin In The Treatment Of Patients With Postherpetic Neuralgiatreatment3completed
NCT01752699
Methadone in Post-Herpetic Neuralgia Paintreatment3completed
NCT01426230
Phase IV Study of FDA Approved, Once-Daily GRALISE™(Gabapentin) Tablets for the Treatment of Postherpetic NeuralgiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01848730
Efficacy and Safety of CNV2197944 Versus Placebo in Patients With Post-herpetic Neuralgiatreatment2completed
NCT00159666
Study of Pregabalin Therapy for Pain Relief in Subjects With Post-Herpetic Neuralgiatreatment4completed
NCT02701374
Efficacy and Safety of TRK-700 in Patient With Post-Herpetic NeuralgiaNo drug interventionstreatment2completed
NCT03745404
A Study With Lido-Patch and Placebo Plaster in Patients Suffering From Postherpetic Neuralgia (PHN)treatment3completed
NCT04144972
Closed-Loop Deep Brain Stimulation for Refractory Chronic PainNo drug interventionstreatmentNot Availablerecruiting
NCT03094195
Dose Response Study of EMA401 in Patients With Post-herpetic Neuralgia (PHN)treatment2terminated
NCT06130514
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Sympathetic Ganglion BlockNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01944150
Association of Transcutaneous Electrical Nerve Stimulation and HypnosisNo drug interventionssupportive_careNot Availablecompleted
NCT05754190
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMANo drug interventionsNot AvailableNot Availablerecruiting
NCT06218784
A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.No drug interventionstreatment1recruiting
NCT06155487
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male SubjectsNo drug interventionstreatment1recruiting
NCT01124097
Eslicarbazepine Acetate as Therapy in Post-Herpetic Neuralgiatreatment3terminated
NCT01250561
Reduction of Postherpetic Neuralgia in Herpes ZostertreatmentNot Availablecompleted
NCT03584061
Treatment of Chronic Postherpetic Pain With Fat GraftingNo drug interventionstreatmentNot Availablecompleted
NCT01037088
Effects of Vaporized Marijuana on Neuropathic Paintreatment1 / 2completed
NCT03447756
Titration Study of ABX-1431treatment1completed
NCT05593237
Transcranial Magnetic Stimulation for Chronic Neuropathic PainNo drug interventionstreatmentNot Availablerecruiting
NCT02633306
Transcranial Magnetic Stimulation for Facial PainNo drug interventionstreatmentNot Availablecompleted
NCT02318719
DS-5565 Phase III Study for Post-herpetic NeuralgiatreatmentNot Availablecompleted
NCT06410222
Predictive Models for the Treatment of Recurrent Herpes Zoster Neuralgia Following Spinal Cord Electrical Stimulation.No drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00305357
Evolution of Pain From Herpes ZosterNo drug interventionsNot AvailableNot Availablecompleted
NCT06241820
The Success of Lumbar Sympathetic Ganglion Block Using Lower Extremity Perfusion IndexNo drug interventionstreatmentNot Availablecompleted
NCT03120962
Effect of Early Use of Oxycodone During the Acute Phase of Herpes Zoster on Preventing Postherpetic NeuralgiatreatmentNot Availableunknown_status
NCT02607280
DS-5565 Phase III Study for Renal Impairment in Japanese Subjectstreatment3completed
NCT00475904
A Comparison of EpiCept™ NP-1 Topical Cream vs. Oral Gabapentin in Postherpetic Neuralgia (PHN)treatment2completed
NCT03974438
Acupuncture as Treatment of Post-herpetic Neuralgia: A RCT A Double-blinded Randomized Clinical Trial.No drug interventionstreatmentNot Availablecompleted
NCT03865953
Oral LAT8881 in Neuropathic PainNo drug interventionstreatment2completed
NCT01455428
Pregabalin for Treatment of Patients With Postherpetic Neuralgia (PHN)treatment4completed
NCT05881811
The Drug-drug Interaction of HSK16149 Capsule With Probenecid Tablets or Cimetidine Tablets in Healthy Subjectsother1completed
NCT05444413
Platelet-rich Plasma in the Treatment of Intractable Postherpetic Neuralgiatreatment1completed
NCT00407511
Pregabalin Treatment Of Peripheral Neuropathic Pain Associated With Diabetic Peripheral NeP (DPN), Postherpetic Neuralgia (PHN), HIV-related NeP (HIV), and Chemotherapy Induced NePtreatment4completed
NCT01713426
A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatmenttreatment4completed
NCT02065349
A Study Into Pain Relief Given by ASP8477 for Peripheral Neuropathic Pain (Either Post-herpetic Neuralgia or Painful Diabetic Peripheral Neuropathy) and Its SafetyNo drug interventionstreatment2completed
NCT01305538
Crossover Post-herpetic Neuralgia (PHN)No drug interventionstreatment2completed
NCT00674687
A Study Of The Efficacy Of Gabapentin In Neuropathic Pain Patients As Measured By Quantitative Sensory TestingNo drug interventionstreatmentNot Availablecompleted
NCT00335933
Safety and Efficacy of Gabapentin in Postherpetic Neuralgiatreatment3completed
NCT00377598
Efficacy, Safety and Tolerability Study of TAK-583 in Subjects With Postherpetic NeuralgiaNo drug interventionstreatment2 / 3completed
NCT03315598
Evaluation of an Effectiveness and Safety of the Electroacupuncture in the Management of Intractable Neuropathic PainNo drug interventionstreatmentNot Availablecompleted
NCT00614705
PH-797804 Versus Placebo For The Treatment Of Neuropathic Pain Associated With Post-Herpetic Neuralgiatreatment2completed
NCT00617461
A Clinical Study in Subjects With Neuropathic Pain From PHN Who Have Had an Inadequate Response to Gabapentin Treatmenttreatment2completed
NCT02426411
Dose Ranging Trial to Determine the Safety and Efficacy of EMA401 in Patients With PHNtreatment2withdrawn
NCT04488835
Pulsed Electromagnetic Field Therapy Versus Transcutaneous Electrical Nerve Stimulation in on Post-herpetic Neuralgia of the Sciatic NerveNo drug interventionstreatmentNot Availablecompleted
NCT00295776
Lamictal in the Treatment of Post-Herpetic NeuralgiaNot Available2 / 3terminated
NCT01252160
Safety and Effectiveness of Repeated Administration of QUTENZA Patches for Treatment of Pain Caused by Nerve Damagetreatment4completed
NCT00245544
Safety and Preliminary Efficacy of MK0759 in Postherpetic Neuralgia (PHN)(0759-004)No drug interventionstreatment2terminated
NCT00160667
A Study Assessing Efficacy of Brivaracetam in Subjects With Persistent Pain After Shingles (Post-herpetic Neuralgia)treatment2completed
NCT01102101
Effect of Opioids in Neuropathic Pain in Postherpetic Patientsbasic_science3unknown_status
NCT00394901
A 13-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Postherpetic Neuralgiatreatment3completed
NCT00160511
A 16 Week Study Evaluating Levetiracetam in the Treatment of Post Herpetic Neuralgia (PHN)Not Available2completed
NCT02484170
Mannitol Cream for Post Herpetic Neuralgiatreatment1 / 2completed
NCT00636636
Safety and Efficacy of Gabapentin in Postherpetic Neuralgiatreatment3completed
NCT01678924
A Safety and Efficacy Study of AGN-214868 in Patients With Postherpetic Neuralgiatreatment2terminated
NCT00282763
A Research Study to Evaluate the Safety and Effectiveness of MK0686 for the Treatment of Postherpetic Neuralgia (Also Known as PHN or Post Shingles Pain) (0686-005)treatment2terminated
NCT03995563
The Effect of Epidural Steroid Use in Patients With Continous Epidural Block in PHN Patients.treatment4unknown_status
NCT01129531
A Study of the Safety and Efficacy of AGN-214868 in Patients With Postherpetic Neuralgiatreatment2completed
NCT00619476
A Study In Patients With Neuropathic Pain From Post-Herpetic Neuralgia (PHN)treatment2completed
NCT00424372
A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Postherpetic Neuralgiatreatment3completed
NCT00570310
Neuropathic Pain Syndrome Patient Study (MK-0000-072)treatment1completed
NCT00964990
A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 in Patients With Neuropathic Pain (Postherpetic Neuralgia and Post-traumatic Neuralgia)treatment2terminated
NCT00568321
RN624 For Pain Of Post-Herpetic Neuralgiatreatment2completed
NCT03708653
Single Nucleotide Polymorphisms (SNPs) Associated With Postherpetic NeuralgiaNo drug interventionsNot AvailableNot Availablecompleted
NCT05357677
To Evaluate the Efficacy and Safety of SR419 in Patients With Postherpetic Neuralgia (PHN)No drug interventionstreatment2completed
NCT01251211
Botulinum Toxin in Peripheral Neuropathic Paintreatment4completed
NCT00238511
An Open-Label Follow-on Trial to Assess the Long-Term Safety and Efficacy of Oral SPM 927 in Subjects With Postherpetic Neuralgia (PHN)treatment2completed
NCT01264237
Evaluation of the Efficacy, Tolerability and Safety of Etoricoxib (Arcoxia) in Patients With Neuropathic Paintreatment4unknown_status
NCT01058642
Study to Assess the Efficacy, Safety, and Tolerability of ADL5747 in Participants With Postherpetic Neuralgiatreatment2terminated
NCT04099706
Treatment of Chronic Postherpetic Pain With Autologous Fat Grafting - A RCTNo drug interventionstreatmentNot Availablecompleted
NCT01195636
A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN)No drug interventionstreatment2completed
NCT02365636
A Study to Evaluate the Safety and Efficacy of Topically Applied TV 45070 Ointment in Patients With Postherpetic Neuralgia (PHN)treatment2completed
NCT05208918
Combined Application of Pulsed RF and Steroids to the DRG for PHNNo drug interventionstreatmentNot Availablecompleted
NCT00168441
A Study Evaluating Botulinum Toxin Type A in Subjects With Postherpetic Neuralgiatreatment2completed
NCT02412917
A Comparative Study of FV-100 vs. Valacyclovir for the Prevention of Post-Herpetic Neuralgiaprevention3terminated
NCT01124617
A Phase 2 Study of Tapentadol Extended-Release (JNS024ER) ) in Japanese Participants With Chronic Pain Due to Diabetic Neuropathic Pain or Postherpetic Neuralgiatreatment2completed
NCT04546334
Erector Spinae Plane Block in Post-herpetic NeuralgiaNo drug interventionssupportive_careNot Availablecompleted
NCT01544296
A Comparative Study of KHK6188No drug interventionstreatment2completed
NCT04774458
Prospective Observation of the Fluoroscopy-guided Cervical Epidural Approach Using the Contralateral Oblique ViewNo drug interventionstreatmentNot Availablecompleted
NCT05140863
To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Postherpetic Neuralgiatreatment3completed
NCT06232486
Relationship Between Serum Vitamin D Levels and Postherpetic Neuralgia.No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00885586
Acupuncture in Herpes Zoster Neuralgia (ACUZoster)treatment4completed
NCT01744522
Leech Therapy for Postherpetic NeuralgiaNo drug interventionsNot AvailableNot Availableterminated
NCT00813826
Efficacy and Safety Study of SLC022 in Treating Pain Associated With Post Herpetic NeuralgiaNo drug interventionstreatment2unknown_status
NCT01318226
Study to Evaluate the Safety and Analgesic Activity of ATx08-001 in Subjects With Postherpetic NeuralgiaNo drug interventionstreatment2completed
NCT01116531
Efficacy, Safety, Tolerability and Pharmacokinetics of Concomitant Administration of Tramadol With Duloxetine or Pregabalintreatment4withdrawn
NCT01757873
Efficacy and Safety Study of Z160 in Subjects With Postherpetic NeuralgiaNo drug interventionstreatment2completed
NCT00981227
Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Post-Herpetic Neuralgiatreatment2completed
NCT02737527
Comparison of the Efficacy of the Ultrasound With Fluoroscopy in Guidance of Lumbar Sympathetic BlocktreatmentNot Availableunknown_status
NCT00007501
Shingles Prevention Studyprevention3completed
NCT00566904
New Topical Treatment for Continued Pain After Shinglestreatment1completed
NCT00861068
A Multi-Centre, Randomized, Double-Blind, Placebo Controlled Pilot Trial to Assess the Efficacy, Safety, and Tolerability of SPM 927 in Subjects With Postherpetic Neuralgia (PHN).treatment2completed
NCT01557010
Evaluate the Efficacy and Safety of DWP05195 in Subjects With Post-Herpetic NeuralgiaNo drug interventionstreatment2completed
NCT00506610
A Study to Determine if an Investigational Pain Medicine Provides Relief of Chronic Pain After a Shingles OutbreakNo drug interventionstreatment2withdrawn
NCT00492323
An Effectiveness and Safety Study With RWJ-333369 (Carisbamate) for the Study of Postherpetic Neuralgia (PHN).treatment2completed
NCT00845923
Evaluation of Civamide Patch in Treatment of Postherpetic Neuralgia and Post-Incisional Neuralgiatreatment2completed
NCT00527202
Efficacy Study of Botox to Treat Neuropathic Paintreatment4completed
NCT00904202
A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditionstreatment4completed
NCT00478179
Study of a Bupivacaine Patch (Eladur™) to Treat Post- Herpetic Neuralgiatreatment2completed
NCT00809679
Analgesic Efficacy and Safety Study of T-62 in Subjects With Postherpetic NeuralgiaNo drug interventionstreatment2terminated
NCT00352651
Study to Find Out if Therapy With the Drug Pregabalin Relieves Pain During Shingles Compared With Placebotreatment2terminated
NCT01008553
A Confirmatory Study of Fentanyl in Participants With Post-herpetic Neuralgia, Complex Regional Pain Syndrome or Postoperative Pain Syndrometreatment3completed
NCT01688947
Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)treatment2completed
NCT04467398
Incidence of Intravascular (IV) Injection During Trigeminal Nerve BlocksNo drug interventionsNot AvailableNot Availablerecruiting
NCT00612105
Safety/Efficacy Study of Retigabine vs. Placebo in Post-Herpetic Neuralgia (PHN)treatment2completed
NCT06290661
Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Postherpetic Neuralgia.No drug interventionstreatmentNot Availablerecruiting
NCT04560361
The Analgesic Effect of Electroacupuncture on Postherpetic NeuralgiaNo drug interventionstreatmentNot Availablerecruiting
NCT02228928
Study of Capsaicin Patch for the Management of Peripheral Neuropathic Paintreatment1 / 2completed
NCT06420778
The Treatment of Postherpetic Neuralgia in the Head and Face With Superficial Needling Combined With ElectroacupuncturetreatmentNot Availablerecruiting
NCT01088256
Efficacy of Etoricoxib on Peripheral Hyperalgesiatreatment2terminated
NCT01302275
Oxcarbazepine for the Treatment of Chronic Peripheral Neuropathic Paintreatment4completed
NCT00916942
Study of NGX-4010 With the Use of Open Label Lidocaine (2.5%)/Prilocaine (2.5%) Cream for the Treatment of Postherpetic Neuralgia (PHN)treatment2completed
NCT01886313
Civamide Nasal Solution for Postherpetic Neuralgia of the Trigeminal Nervetreatment2terminated
NCT01106716
Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgiatreatment2completed
NCT01379716
Evaluation of Five Selected Markers in Skin Biopsies of Patients With Postherpetic Neuralgia and Healthy ControlsNo drug interventionsdiagnosticNot Availablecompleted
NCT03106896
Involvement of Reorganization of Cerebral Functional Connectivity in the Process of Transition to Postherpetic NeuralgiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04313335
Duloxetine for PHNpreventionNot Availablecompleted
NCT05517486
Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjectstreatment1unknown_status
NCT05568186
Correlation Between Thermal Patterns of Infrared Thermal Imaging and Clinical Phenotype in Patients With Postherpetic NeuralgiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT04664530
The Study on the Esketamine in the Treatment of Postherpetic Neuralgiatreatment4unknown_status
NCT02597257
Efficacy and Safety of Lidocaine Infusion Treatment in Management of Neuropathic Paintreatment2unknown_status
NCT04594226
Electroacupuncture Therapy for Treating Postherpetic NeuralgiaNo drug interventionstreatmentNot Availablecompleted
NCT00904020
A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralgia, Diabetic Neuropathy, or Low Back Paintreatment4completed
NCT01508676
Effects of Pennsaid on Clinical Neuropathic PainNot AvailableNot Availablecompleted
NCT06225960
Dorsal Root Ganglion Stimulation in Postherpetic NeuropathyNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT01603394
Pilot Study Of Pregabalin And Prediction Of Treatment Response In Patients With Postherpetic Neuralgiatreatment4terminated
NCT01596491
Study of Possible Changes in QST After Application of Capsaicin on Patients With Peripheral Neuropathic PainNo drug interventionsNot AvailableNot Availablecompleted
NCT04876989
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral BlockNo drug interventionstreatmentNot Availablecompleted
NCT02868801
Efficacy and Safety of Pregabalin Sustained Release Tablet for Postherpetic Neuralgiatreatment3unknown_status
NCT04662281
Efficacy and Safety of LX9211 in Participants With Postherpetic NeuralgiaNo drug interventionstreatment2completed
NCT03789955
The Superiority of Contralateral Oblique View for Mid-thoracic Epidural AssessNo drug interventionsdiagnosticNot Availablecompleted
NCT02336555
The Efficacy of MK-8291 in Participants With Post-herpetic Neuralgia (PHN) With Allodynia (MK-8291-012)No drug interventionstreatment1completed
NCT00609323
Lidocaine and Tetracaine Cream to Treat Postherpetic Neuralgia (PHN)treatment2completed
NCT00576108
A 2 Week Study of Topical KD7040 in the Treatment of Postherpetic Neuralgia (PHN)treatment2completed
NCT00599638
A Study To Compare Pregabalin/PF-00489791 Combination Versus Pregabalin Alone In Post-Herpetic Neuralgiatreatment2completed
NCT01228838
Study of NGX-1998 for the Treatment of Postherpetic Neuralgiatreatment2completed
NCT00652184
Study to Compare Efficacy of Topical ARYS-01 (Sorivudine) Cream 3%, Oral Valaciclovir and Combination ARYS-01 Cream 3%/Oral Valaciclovir for Treatment of Herpes Zoster (Shingles)treatment2unknown_status