Soft Tissue Sarcoma (DBCOND0029966)

Identifiers

Synonyms
Sarcoma of Soft Tissue / Soft-tissue Sarcomas / Soft-Tissue Sarcoma / Sarcoma, Soft-tissue / Soft Tissue Sarcoma (STS) / Soft Tissue Sarcomas / Sarcoma,Soft Tissue / Sarcoma, Soft Tissue / Soft tissue sarcoma / Non-rhabdomyosarcoma soft-tissue sarcoma / Sarcoma of soft tissue (disorder) / Sarcoma (morphologic abnormality) / Sarcoma NOS / Sarcoma / Sarcoma (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Docetaxel
A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
Epirubicin
An anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer.
Ifosfamide
An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
Methotrexate
An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
Olaratumab
A platelet-derived growth factor receptor alpha blocking antibody used with doxorubicin to treat patients with certain types of soft tissue sarcoma (STS).
Temozolomide
An alkylating agent used to treat glioblastoma multiforme and refractory anaplastic astrocytoma.
Vinorelbine
A vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03284320
Retrospective Study in Sarcoma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02805725
Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly Trabectedin Combined With Metronomic Cyclophosphamidetreatment1 / 2completed
NCT02789384
CINSARC Signature and Correlation With Hemotherapy Efficacy in Soft-tissue Sarcomas. A Biomarker Study.No drug interventionsotherNot Availablerecruiting
NCT06535997
Descriptive Cohort of French Patients Treated With Carbonetherapy Since October 2010 Outside PHRC-ETOILENo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06308419
A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or DeletionsNo drug interventionstreatment1recruiting
NCT03602833
Phase I Study Compound 451238 and Radiotherapy in Soft-tissue SarcomaNo drug interventionstreatment1 / 2unknown_status
NCT02787642
A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue Sarcomatreatment1completed
NCT03242382
Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression.treatment2recruiting
NCT05741944
The Value of a Risk Prediction Tool (PERSARC) for Effective Treatment Decisions of Soft-tissue Sarcomas PatientsNo drug interventionssupportive_careNot Availablerecruiting
NCT02630368
A Study of Metronomic CP and JX-594 in Patients With Advanced Breast Cancer and Advanced Soft-tissue Sarcoma (METROmaJX)No drug interventionstreatment1 / 2recruiting
NCT01389050
High Precision RT For Soft-Tissue SarcomaNo drug interventionstreatment2completed
NCT01438554
Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and CholangiocarcinomaNo drug interventionsother1completed
NCT03475953
A Phase I/II Study of Regorafenib Plus Avelumab in Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT03007771
Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild HyperthermiaNo drug interventionsdevice_feasibility1withdrawn
NCT02987959
Study of TAK-228 (MLN0128) in Soft Tissue SarcomasNo drug interventionstreatment2terminated
NCT04181970
Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORKNo drug interventionsNot AvailableNot Availablerecruiting
NCT03175718
INPWT on Wound Complications & Clinical Outcomes After Lower Extremity Sarcoma Surgery Preop Radiation Therapy PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT03016819
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)No drug interventionstreatment3active_not_recruiting
NCT03096912
A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated LiposarcomaNo drug interventionstreatment2unknown_status
NCT01543802
Study of Preoperative Therapy With Pazopanib (Votrient®) to Treat High-risk Soft Tissue SarcomaNo drug interventionstreatment2terminated
NCT01594203
Contribution of F18-FDG PET/CT to the Early Assessment of Pazopanib Therapy Efficacy in Advanced Soft Tissue SarcomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05497843
Chiauranib for Advanced or Unresectable Soft Tissue Sarcoma(STS)No drug interventionstreatment2active_not_recruiting
NCT04318964
TAEST16001 in the Treatment of Soft Tissue SarcomaNo drug interventionstreatment1active_not_recruiting
NCT05301764
A Study of LVGN6051 Combined With Anlotinib in Patient With Soft Tissue SarcomaNo drug interventionstreatment1 / 2recruiting
NCT05111964
HIFU Ablation of Soft Tissue SarcomaNo drug interventionstreatmentNot Availablerecruiting
NCT00629343
Phase I Dose-Escalation Study Of Azacitidine In Combination With TemozolomideNo drug interventionstreatment1unknown_status
NCT02192333
Survivorship Care in Reducing Symptoms in Young Adult Cancer SurvivorsNo drug interventionssupportive_careNot Availablecompleted
NCT05761054
Sarcoma Preoperative Radiation With Simultaneous INTegrated Boost (SPRINT)No drug interventionstreatmentNot Availablerecruiting
NCT01575951
Pilot Study: Dynamic Contrast-enhanced Magnetic Resonance Imaging(DCE-MRI)for Assessing Tumor Vascularity and Permeability in Soft Tissue Sarcoma Treated With Preoperative Radiotherapy Followed by Surgical ResectionNo drug interventionsscreeningNot Availablecompleted
NCT05539677
Biobank and Register of Patients With Agresive Tumors for Translational and Analytical ResearchNo drug interventionsNot AvailableNot Availablerecruiting
NCT02300545
Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapytreatment2completed
NCT05655598
TAS-116 Plus Palbociclib in Breast and Rb-null Cancertreatment1recruiting
NCT03524898
NAPAGE: NAb-PAclitaxel and GEmcitabine in Advanced Soft Tissue Sarcomatreatment1 / 2terminated
NCT06264505
Investigative Analysis of Soft Tissue Sarcoma Clinical Trials: An Observational StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04040205
Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alterationtreatment2recruiting
NCT05955105
A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignanciestreatment1 / 2recruiting
NCT06526897
Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue SarcomaNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT00087997
A Study of STA-4783 in Combination With Weekly Paclitaxel for Treatment of Patients With Soft Tissue Sarcomastreatment2completed
NCT04733183
Efficacy and Safety of L19TNF in Previously Treated Patients With Advanced Stage or Metastatic Soft-tissue Sarcomatreatment2recruiting
NCT05189483
Albumin-bound Paclitaxel Plus Camrelizumab for Advanced Soft Tissue Sarcoma.treatment2recruiting
NCT02267083
Efficacy and Safety Study of GPX-150 to Treat Soft Tissue Sarcomatreatment2completed
NCT00998361
Hematopoietic Stem Cell Transplantation From Human Leukocyte Antigen (HLA) Compatible Donor in Ewing Sarcomas and Soft Tissues SarcomasNo drug interventionstreatment2unknown_status
NCT02204111
Patient Directed Intervention to Improve the Quality of Life for Patients With Soft Tissue SarcomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02706171
Stereotactic Radiosurgery for Soft Tissue SarcomaNo drug interventionstreatmentNot Availablewithdrawn
NCT00611078
Environmental Pollutants and the Risk of Soft Tissue Sarcoma: A Pilot StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02624388
Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)supportive_care2terminated
NCT03867188
Liposomal Bupivacaine (Exparel) in Sarcomassupportive_care0terminated
NCT02584309
Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcomatreatment2completed
NCT00102609
A Safety Study Utilizing Yondelis and Doxorubicin in Patients With a Type of Cancer Called Soft Tissue Sarcomatreatment1completed
NCT03345485
Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumorstreatment1 / 2completed
NCT01803152
Dendritic Cell Vaccine for Children and Adults With Sarcomatreatment1completed
NCT02945800
Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcomatreatment2active_not_recruiting
NCT05926700
Efficacy and Safety of Cadonilimab Plus Anlotinib in Advanced STS That Failed the Previous First-line Standard TreatmentNo drug interventionstreatment2recruiting
NCT06022159
A Study to Evaluate Pre- or Post-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.No drug interventionstreatment2recruiting
NCT03338959
Pembrolizumab and Radiation Therapy in Treating Patients With Intermediate or High-Grade Soft Tissue Sarcomatreatment1 / 2completed
NCT01296659
Study of Oral Ridaforolimus in Combination With Standard Chemotherapy for Soft Tissue Sarcomatreatment1withdrawn
NCT03520959
A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)treatment3terminated
NCT05051059
Assessment of the Functional Outcome and Quality of Life in Sarcoma PatientsNo drug interventionsotherNot Availablerecruiting
NCT04288375
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and LegsNo drug interventionstreatment2recruiting
NCT01259375
Amrubicin Chemotherapy as First Line in Metastatic or Unresectable Soft Tissue Sarcomatreatment2completed
NCT03468075
Gemcitabine Plus Ascorbate for Sarcoma in Adultstreatment2terminated
NCT03792542
Anlotinib Hydrochloride For Advanced Soft Tissue Sarcoma Patients Who Do Not Receive Chemotherapytreatment2unknown_status
NCT02783599
A Study of Olaratumab (LY3012207) in Participants With Soft Tissue Sarcomatreatment1completed
NCT02775799
National Swiss Sarcoma Cohort StudyNo drug interventionsNot AvailableNot Availableterminated
NCT03913806
FLuoresence Image Guided Surgery With A VEGF-targeted Tracer in Soft-tissue Sarcomas in Humans Approach With Bevacizumab-IRDye 800CWdiagnostic1 / 2completed
NCT01299506
Study in Patients With Advanced Soft Tissue Sarcoma (STS) After Failure of Anthracyclines and/or IfosfamideNo drug interventionsNot AvailableNot Availablecompleted
NCT01458249
An Open-label, Multicenter, Phase 2 Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Previously Treated Subjects With Advanced or Metastatic Soft Tissue Sarcoma (Study E7389-J081-217)treatment2completed
NCT05944913
Study Comparing Negative Pressure Dressing vs Conventional in Patients With Resected STS After RadiotherapyNo drug interventionsotherNot Availablerecruiting
NCT05171413
Predictive Models of Treatment Responses and Survival Outcomes in Patients With Soft Tissue SarcomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05755113
A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcomatreatment2recruiting
NCT01812018
Endostar + GT in Pulmonary Metastases of Soft Tissue Sarcomatreatment2unknown_status
NCT03042819
Study of Selinexor and Doxorubicin in Advanced Soft Tissue Sarcomastreatment1completed
NCT02795819
Study of the Pan-DAC Inhibitor AR-42 and Pazopanib in Advanced Sarcoma and Kidney Cancertreatment1terminated
NCT04589741
Toripalimab Combined With CAV/IE Regimentreatment2recruiting
NCT04921917
Exercise and Soft Tissue SarcomaNo drug interventionstreatmentNot Availablerecruiting
NCT01347034
Radiation Therapy and Intratumoral Autologous Dendritic Cells in Soft Tissue Sarcomas (STS)No drug interventionstreatment2completed
NCT03967834
Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma GroupNo drug interventionsotherNot Availablerecruiting
NCT05886634
A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcomatreatment2recruiting
NCT03277924
Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomastreatment1 / 2completed
NCT06537596
89Zr-olaratumab Dosimetry in Participants With Soft Tissue Sarcomadiagnostic1not_yet_recruiting
NCT03916796
Rehabilitation and Quality of Life Assessment for Soft Tissue Sarcoma Treated With Radiotherapy and SurgeryNo drug interventionssupportive_careNot Availableterminated
NCT05328258
Use of GnRHa During Chemotherapy for Fertility Protectiontreatment3recruiting
NCT02890758
Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803treatment1completed
NCT04969835
A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid TumoursNo drug interventionstreatment1recruiting
NCT01498835
Safety Study of Preoperative Sunitinib and Radiation in Soft Tissue Sarcomatreatment1completed
NCT02432963
Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapytreatment1active_not_recruiting
NCT02982486
A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinomatreatment2unknown_status
NCT00188422
Study of Low Dose CT in Sarcoma PatientsNo drug interventionsdiagnostic1completed
NCT04776525
Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcomatreatment2recruiting
NCT03085225
Trabectedin Combined With Durvalumab in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas.treatment1completed
NCT04165330
Evaluation of AL3818 in Combination With Nivolumab in Solid Tumorstreatment1 / 2active_not_recruiting
NCT01382030
Neoadjuvant and Adjuvant Chemotherapy in High-risk Soft Tissue SarcomaNo drug interventionstreatment2completed
NCT02632448
A Study of LY2880070 in Participants With Advanced or Metastatic Cancerbasic_science1 / 2recruiting
NCT00525057
Dalteparin in Preventing DVT in Participants With CancerNo drug interventionspreventionNot Availablecompleted
NCT04579757
Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumorstreatment1 / 2active_not_recruiting
NCT04946357
Neoadjuvant Irradiation of Extremity Soft Tissue Sarcoma With IonsNo drug interventionstreatmentNot Availablerecruiting
NCT03508726
High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomastreatment1 / 2completed
NCT05518526
Phase 1b/2 Study of Liposomal Annamycin (L-Annamycin) in Subjects With Previously Treated Soft-Tissue Sarcomas (STS) With Pulmonary Metastasestreatment1 / 2recruiting
NCT01095926
Pharmacokinetic Study of Doxorubicin in Children With Cancertreatment2completed
NCT03217266
Navtemadlin and Radiation Therapy in Treating Patients With Soft Tissue Sarcomatreatment1active_not_recruiting
NCT01626066
Cathepsin Activatable Fluorescent ProbeNo drug interventionsdiagnostic1completed
NCT04118166
Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcomatreatment2completed
NCT06500065
68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue SarcomasNo drug interventionsdiagnosticNot Availablerecruiting
NCT01904565
Hyperthermia and Proton Therapy in Unresectable Soft Tissue SarcomaNo drug interventionstreatment1 / 2unknown_status
NCT05596565
The Effects of Observer Presence and Type on Patients' Perception of Exercise in Patients With Soft Tissue SarcomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05938374
Preoperative Moderately Fractionated IMRT for Locally Extremity or Trunk Sarcomatreatment2recruiting
NCT03244020
LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncologyprevention4enrolling_by_invitation
NCT00580320
Safety Study of Dacarbazine and Bortezomib in Melanoma and Soft Tissue SarcomaNo drug interventionstreatment1completed
NCT01427582
YONDELIS (Trabectedin) Single Patient Compassionate Use / Expanded AccessNot AvailableNot Availableno_longer_available
NCT00876031
Trial for Localised High-risk Rhabdomyosarcoma and Rhabdomyosarcoma-like Soft Tissue Sarcomatreatment3completed
NCT05142631
Fruquintinib in the Treatment of Soft Tissue Sarcomatreatment2unknown_status
NCT05821231
Study Evaluating the Safety and Efficacy of MEDI5752 in Combination With Stereotactic Radiotherapy in Patients With Metastatic Sarcomatreatment1recruiting
NCT04725331
A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumorstreatment1 / 2recruiting
NCT00931931
HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid TumorsNo drug interventionstreatment1completed
NCT05582031
Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancerstreatment2withdrawn
NCT05420727
Theranostics in Soft Tissue Sarcoma Using a Vascular Disruption Approachtreatment1completed
NCT04634227
Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)No drug interventionstreatment0recruiting
NCT03994627
Olaratumab (LY3012207) Patient Access for Soft Tissue SarcomaNot AvailableNot Availableavailable
NCT06252727
Fluorescent Aided Resection and Evaluation of Soft Tissue Sarcomas (FLARES)treatment1withdrawn
NCT04037527
Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremitiestreatment1suspended
NCT01696760
Aspirin and Compression Devices for VTE Prophylaxis in Orthopaedic Oncologysupportive_careNot Availablecompleted
NCT05000294
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Typestreatment1 / 2recruiting
NCT05712694
Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)treatment3recruiting
NCT05109494
Hypofractionated vs Conventional Fractionated RT in Soft Tissue SarcomasNo drug interventionstreatment2recruiting
NCT05950594
IVIM & OLINK in SarcomaNo drug interventionsdiagnostic2recruiting
NCT03365791
PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignanciestreatment2completed
NCT05688280
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STSNo drug interventionstreatment1 / 2recruiting
NCT03116529
Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue SarcomaNo drug interventionstreatment1 / 2active_not_recruiting
NCT02571829
A Phase II Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcomatreatment2unknown_status
NCT00615329
Huntsman Biopsy StudyNo drug interventionsNot AvailableNot Availableterminated
NCT00413192
E7389 Administered as an IV Bolus Infusion Day 1 and Day 8 Every 3 Weeks in Pre-Treated Patients With Advanced and/or Metastatic Soft Tissue SarcomaNo drug interventionstreatment2completed
NCT06566092
Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult ParticipantsNo drug interventionstreatment1recruiting
NCT03899792
A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) TumorsNo drug interventionstreatment1 / 2recruiting
NCT04553744
Identification of Surgical Management of Lymph Node Basins and Surgical Practice Patterns Among Sarcoma SurgeonsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03452644
US-Guided Biopsy in the Diagnosis of Musculoskeletal Soft-Tissue TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT00288444
Interaction of Docetaxel and Lonafarnib in Patients With Advanced CancerNo drug interventionstreatment1terminated
NCT00541840
Phase I-II Trial of Sorafenib in Combination With Ifosfamide in Soft Tissue SarcomaNo drug interventionstreatment1 / 2unknown_status
NCT05917301
Pre-operative Hypofractionated Proton TherapyNo drug interventionstreatmentNot Availablerecruiting
NCT03449901
ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung CancerNo drug interventionstreatment2completed
NCT00626704
Phase 1b/2 Study of AMG 655 With Doxorubicin for the First-Line Treatment of Unresectable Soft Tissue SarcomaNo drug interventionstreatment1 / 2completed
NCT03076372
A Study Evaluating MM-310 in Patients With Solid TumorsNo drug interventionstreatment1unknown_status
NCT01106872
Bevacizumab, Chemotherapy and Valproic Acid in Advanced SarcomasNo drug interventionstreatment1completed
NCT02890368
Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis FungoidesNo drug interventionstreatment1terminated
NCT03890068
Anlotinib Maintenance Treatment for Advanced Soft Tissue SarcomaNo drug interventionstreatment2recruiting
NCT01807468
Haploidentical Stem Cell Transplantation and NK Cell Therapy in Patients With High-risk Solid TumorsNo drug interventionstreatment2unknown_status
NCT01505569
Auto Transplant for High Risk or Relapsed Solid or CNS TumorsNo drug interventionsotherNot Availablecompleted
NCT01612481
Phase II Study Evaluating Strategies of Lung Surveillance of Patients Operated of High Grade Soft Tissue SarcomaNo drug interventionsprevention2terminated
NCT03514381
Pharmacologic Interaction Between Ifosfamide and Aprepitant in Treated Patients With Soft Tissue SarcomaNo drug interventionstreatment4completed
NCT02910895
A Platform of Patient Derived Xenografts (PDX) and 2D/3D Cell Cultures of Soft Tissue Sarcomas (STS)No drug interventionsbasic_scienceNot Availablerecruiting
NCT05057195
Wide Excision of Soft Tissue Sarcomas in Combination With Interstitial Radiation TherapyNo drug interventionstreatmentNot Availablerecruiting
NCT02784795
A Study of LY3039478 in Participants With Advanced or Metastatic Solid TumorsNo drug interventionstreatment1completed
NCT00898755
Collecting and Storing Tissue From Young Patients With CancerNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02811523
In Vivo Lung Perfusion for Pulmonary Metastases of SarcomaNo drug interventionstreatment1recruiting
NCT04606108
Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of High-risk Soft Tissue SarcomaNo drug interventionstreatment2unknown_status
NCT03064243
A Phase II Study of Apatinib in STS PatientsNo drug interventionstreatment2unknown_status
NCT04239443
Clinical Study of PD-1 Monoclonal Antibody SHR-1210 and Apatinib in Advanced NSCLC, Soft Tissue Sarcoma, and Uterine CancerNo drug interventionstreatment2unknown_status
NCT02449343
Study of Anlotinib in Patients With Soft Tissue Sarcoma(STS)(ALTER0203)No drug interventionstreatment2 / 3unknown_status
NCT04995003
HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced SarcomaNo drug interventionstreatment1recruiting
NCT06129903
Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With SarcomaNo drug interventionspreventionNot Availablerecruiting
NCT06216990
Metastatic or Refractory Soft Tissue Sarcomas and Metronomic Cyclophosphamide: Further Assessment of Efficacy and SafetyNo drug interventionsNot AvailableNot Availablecompleted
NCT01663090
Ferumoxytol-Enhanced MRI in Adult/Pedi SarcomasNo drug interventionsdiagnosticNot Availablewithdrawn
NCT04032964
Dose Finding Study of L19TNF and Doxorubicin in Patients With STSNo drug interventionstreatment1active_not_recruiting
NCT05747521
Anrotinib Hydrochloride Combined With Adriamycin for Neoadjuvant Treatment of High-grade Soft Tissue SarcomaNo drug interventionstreatmentNot Availablerecruiting
NCT05549921
Phase II Study of TAEST16001 in Soft Tissue SarcomaNo drug interventionstreatment2recruiting
NCT05679921
Pazopanib With or Without Pembrolizumab for Metastatic Soft Tissue SarcomaNo drug interventionstreatment2not_yet_recruiting
NCT00003521
Antineoplaston Therapy in Treating Patients With Soft Tissue Sarcomatreatment2terminated
NCT04897321
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)No drug interventionstreatment1recruiting
NCT04650984
A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue SarcomaNo drug interventionstreatment3recruiting
NCT00718484
A Study of Palifosfamide Tris Plus Doxorubicin Versus Doxorubicin in Unresectable or Metastatic Soft-tissue SarcomaNo drug interventionstreatment2unknown_status
NCT02581384
Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms TumorsNo drug interventionstreatment1 / 2terminated
NCT04877587
Gemcitabine With Ascorbate Including AdolescentsNo drug interventionstreatment0withdrawn
NCT06494787
A Phase 2 Study Using Aliya PEF Plus Pembro for SarcomaNo drug interventionstreatment2not_yet_recruiting
NCT04589754
Adriamycin and Ifosfamide Combined With SintilimabNo drug interventionstreatment2recruiting
NCT01861951
A Trial Comparing Two Medications as First Treatment in Elderly Patients With Metastatic or Advanced Soft Tissue SarcomaNo drug interventionstreatment2completed
NCT05355753
A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null TumorsNo drug interventionstreatment1 / 2terminated
NCT04055753
Study to Assess TOPO2A as a Biomarker for Sensitivity to Doxorubicin/Doxil in Soft Tissue SarcomaNot AvailableNot Availableactive_not_recruiting
NCT01650077
Therapeutic Response of Patients With Soft Tissue Sarcoma According to CHOI CriteriaNo drug interventionsNot AvailableNot Availablecompleted
NCT03730077
FMISO PET/CT Imaging Trial for Assessing Hypoxia in Soft Tissue SarcomasNo drug interventionsother1terminated
NCT04307277
Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue SarcomaNo drug interventionstreatment3recruiting
NCT05697198
PRospective rEgistry OF Advanced Stage cancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision MedicineNo drug interventionsNot AvailableNot Availablerecruiting
NCT03944798
Surveillance AFter Extremity Tumor surgerYNo drug interventionspreventionNot Availablerecruiting
NCT03725605
LTX-315 and Adoptive T-cell Therapy in Advanced Soft Tissue Sarcoma (ATLAS-IT-04)No drug interventionstreatment2completed
NCT01005797
Study of Panobinostat in Combination With Sorafenib in Kidney, Soft Tissue or Lung CancersNo drug interventionstreatment1completed
NCT02080897
Evaluating Quality of Life in Patients With Soft Tissue Sarcoma Presenting With Metastatic Lung DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00755261
Phase II Study of Doxorubicin and Avastin® in Sarcoma.No drug interventionstreatment2terminated
NCT06087861
5-Day Preoperative Radiation for Soft Tissue SarcomaNo drug interventionstreatment2recruiting
NCT03168061
Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue SarcomaNo drug interventionstreatment1 / 2unknown_status
NCT01055028
Paclitaxel + Bevacizumab (Avastin) for the Treatment of Metastatic or Unresectable AngiosarcomaNo drug interventionstreatment2terminated
NCT04791228
A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid TumorsNo drug interventionstreatment2recruiting
NCT04126811
Apatinib Combined With Chemotherapy in the Treatment of Soft Tissue SarcomaNo drug interventionstreatment2unknown_status
NCT00502411
Post-Operative Chemoradiation for Extremity & Trunk Soft Tissue SarcomaNo drug interventionstreatment1completed
NCT05432193
FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER)No drug interventionstreatment1active_not_recruiting
NCT04483778
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young AdultsNo drug interventionstreatment1active_not_recruiting
NCT01896778
Body Warming in Improving Blood Flow and Oxygen Delivery to Tumors in Patients With CancerNo drug interventionsbasic_scienceNot Availablecompleted
NCT06117878
Safety and Efficacy of NK510 to Treat Osteosarcoma and Soft Tissue SarcomaNo drug interventionstreatment0recruiting
NCT05718778
Piamprilizumab (AK105) Combined With Radiotherapy for Neoadjuvant Treatment of Soft Tissue SarcomaNo drug interventionstreatmentNot Availablerecruiting
NCT02923778
Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by SurgeryNo drug interventionstreatment2active_not_recruiting
NCT03900078
Incisional Negative Pressure Wound Therapy for Resection of Soft Tissue TumorsNo drug interventionstreatmentNot Availablecompleted
NCT01440088
A Trial of TH-302 in Combination With Doxorubicin Versus Doxorubicin Alone to Treat Patients With Locally Advanced Unresectable or Metastatic Soft Tissue SarcomaNo drug interventionstreatment3completed
NCT04518488
Prehabilitation Soft-Tissue Sarcoma of Lower LimbNo drug interventionsotherNot Availableunknown_status
NCT00038207
Liposomal Vincristine for Pediatric and Adolescent Patients With Relapsed Malignanciestreatment2completed
NCT05560009
An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue SarcomasNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01327885
Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Dacarbazine in Subjects With Soft Tissue SarcomaNo drug interventionstreatment3completed
NCT05602415
Anlotinib and Radiotherapy in Resectable Soft Tissue SarcomaNo drug interventionstreatment2recruiting
NCT01140737
A Study of Axitinib in Patients With Advanced Angiosarcoma and Other Soft Tissue SarcomasNo drug interventionstreatment2completed
NCT03375437
RNASARC - Molecular Screening Program of Soft Tissue Sarcomas With Complex Genomic Profile to Detect NTRK1/2/3, ROS1 or ALK Gene Fusions.No drug interventionsscreeningNot Availableactive_not_recruiting
NCT00864032
Trial of Neoadjuvant Conformal Radiotherapy Plus Sorafenib for Patients With Soft Tissue Sarcoma of the Extremity and Body WallNo drug interventionstreatment1 / 2completed
NCT01392352
HYPAZ: Hypertension Induced by PazopanibNo drug interventionsbasic_science2terminated
NCT05116800
Phase 2 Study of 9-ING-41 With Chemotherapy in SarcomaNo drug interventionstreatment2withdrawn
NCT01136499
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment FailureNo drug interventionstreatment2completed
NCT06202599
Fruquintinib-based Treatment for Refractory Bone and Soft Tissue Sarcomas After Several Lines of TKIs' ResistanceNo drug interventionsNot AvailableNot Availablecompleted
NCT04166006
A Phase II Study on Adjuvant Vaccination With Dendritic Cells Loaded With Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.No drug interventionstreatment2recruiting
NCT01135849
B-Receptor Signaling in CardiomyopathyNo drug interventionsNot AvailableNot Availablecompleted
NCT06514313
Clinical Trial of VIM With VIT in Children With Relapsed and Refractory Soft Tissue Sarcoma.No drug interventionstreatment2recruiting
NCT06409013
Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With SarcomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT04383119
Trial in Patients With Metastatic or Locally Advanced LeiomyosarcomaNo drug interventionstreatment2recruiting
NCT05597917
tTF-NGR Randomized Study - STSNo drug interventionstreatment3recruiting
NCT05526417
Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue SarcomaNo drug interventionssupportive_careNot Availablerecruiting
NCT05224934
Preoperative Ultra-hypofractionated Radiotherapy Followed by Surgery for Retroperitoneal SarcomaNo drug interventionstreatment2recruiting
NCT06050434
Prospective Study to Evaluate Patient Reported Outcomes (PRO) During Rechallenge With Trabectedin in Sarcoma PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01136824
Chemotherapy-induced Symptoms in Sarcoma Patients and the Impact of Tumor BurdenNo drug interventionsNot AvailableNot Availablecompleted
NCT02367924
Efficacy and Safety of Trabectedin (Yondelis®) in Patients With Advanced Soft Tissue SarcomaNo drug interventionsNot AvailableNot Availablecompleted
NCT03462316
NY-ESO-1-specific T Cell Receptor (TCR) T Cell in SarcomaNo drug interventionstreatment1active_not_recruiting
NCT00179816
Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumorstreatment1 / 2unknown_status
NCT04811196
A Study of Different Dosing Schedules of Selinexor in Sarcoma PatientsNo drug interventionstreatment1active_not_recruiting
NCT03957096
A Safety Study of SGN-CD47M in Patients With Solid TumorsNo drug interventionstreatment1terminated
NCT06551896
Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid TumorNo drug interventionstreatment2not_yet_recruiting
NCT03283696
A Study of Olaratumab (LY3012207), Doxorubicin, and Ifosfamide in Participants With Advanced or Metastatic Soft Tissue SarcomaNo drug interventionstreatment1completed
NCT02398058
Trabectedin Plus Olaparib in Metastatic or Advanced Sarcomas (TOMAS)No drug interventionstreatment1completed
NCT02628535
Safety Study of MGD009 in B7-H3-expressing TumorsNo drug interventionstreatment1terminated
NCT03220035
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)No drug interventionstreatment2active_not_recruiting
NCT00742963
Dose-Escalation Study of TH-302 in Combination With Doxorubicin to Treat Patients With Advanced Soft Tissue SarcomaNo drug interventionstreatment1 / 2completed
NCT02270086
Evaluating Bacterial Response in Sarcoma Management Using Fluorescence ImagingNo drug interventionsNot AvailableNot Availablecompleted
NCT05131386
Multicohort Trial of Trabectedin and Low-dose Radiation Therapy in Advanced/Metastatic SarcomasNo drug interventionstreatment2recruiting
NCT02301039
SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced SarcomasNo drug interventionstreatment2completed
NCT00717522
Efficacy and Safety Study of CC-4047 (Pomalidomide) to Treat Advanced Soft Tissue SarcomaNo drug interventionstreatment2terminated
NCT01802125
Biomarker Differences in Samples From Patients With Undifferentiated SarcomasNo drug interventionsNot AvailableNot Availablecompleted
NCT03719430
APX005M and Doxorubicin in Advanced SarcomaNo drug interventionstreatment2active_not_recruiting
NCT03972930
Hypofractionated Radiotherapy for Soft Tissue SarcomasNo drug interventionstreatment2active_not_recruiting
NCT04616248
In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid TumorsNo drug interventionstreatment1recruiting
NCT04910126
Camrelizumab Plus Doxorubicin for the First Line Treatment of Adcanced Soft Tissue SarcomaNo drug interventionstreatment2unknown_status
NCT00194766
Continuous Temozolomide in Patients With Advanced or Metastatic Soft Tissue Sarcoma or Metastatic Breast Cancertreatment2completed
NCT05684874
Multiparametric Quantitative MRI and Response to Neoadjuvant Radiotherapy for Soft-tissue SarcomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT06332274
tislelizUMaB in canceR Patients With molEcuLar residuaL DiseaseNo drug interventionstreatment3not_yet_recruiting
NCT05448820
YH001 Plus Envafolimab With or Without Doxorubicin in Patients With Advanced or Metastatic SarcomaNo drug interventionstreatment1 / 2active_not_recruiting
NCT02659020
A Study of Olaratumab (LY3012207) in Participants With Advanced Soft Tissue SarcomaNo drug interventionstreatment1 / 2completed
NCT06171282
A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Bone and Soft Tissue TumorsNo drug interventionstreatment0recruiting
NCT01819831
A Phase II Trial of Preoperative Proton Therapy in Soft-tissue Sarcomas of the Extremities and Body WallNo drug interventionstreatmentNot Availablecompleted
NCT00356031
Bevacizumab and Radiation Therapy for SarcomasNo drug interventionstreatment2completed
NCT03546127
Molecular Profiling to Improve Outcome of Patients in Cancer. A Pilot StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00753727
Sunitinib and Radiation in Patients With Resectable Soft-tissue SarcomaNo drug interventionstreatment1 / 2unknown_status
NCT04012827
Apatinib Mesylate Combined With Doxorubicin and Ifosfamide in Advanced Soft-tissue SarcomaNo drug interventionstreatment2unknown_status
NCT02672527
Trial Comparing Trabectedin to the Best Supportive Care in Patients With SarcomaNo drug interventionstreatment3completed
NCT05813327
Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue SarcomaNo drug interventionstreatment1 / 2recruiting
NCT03114527
Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)No drug interventionstreatment2active_not_recruiting
NCT02547376
Genetic and Telomere Characteristics of High of Grade Soft Tissue SarcomasNo drug interventionsNot AvailableNot Availableterminated
NCT04906876
A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced SarcomasNo drug interventionstreatment2withdrawn
NCT03960060
A Study of CCT301-59 CAR T Therapy in Adult Subjects With Recurrent or Refractory Solid TumorsNo drug interventionstreatment1unknown_status
NCT01303094
Continuing vs Intermittent Trabectedin in Patients With Advanced Soft Tissue SarcomaNo drug interventionstreatment2completed
NCT06500091
TQB2916 Injection Combined With Chemotherapy or Penpulimab Injection in the Treatment of Solid TumorsNo drug interventionstreatment2not_yet_recruiting
NCT03126591
A Study of Olaratumab (LY3012207) Plus Pembrolizumab in Participants With Advanced or Metastatic Soft Tissue SarcomaNo drug interventionstreatment1completed
NCT01168791
Study of Palifosfamide-tris in Combination With Doxorubicin in Patients With Front-line Metastatic Soft Tissue SarcomaNo drug interventionstreatment3completed
NCT02453191
TVEC and Preop Radiation for Sarcoma (4 ml Dose)No drug interventionstreatment1 / 2completed
NCT04599062
TVEC and Preop Radiation for Sarcoma (8 ml Dose)No drug interventionstreatment1 / 2active_not_recruiting
NCT06317480
Outcomes Comparison Between Bone Resection and Subperiosteal Dissection for Specific Type of Soft Tissue SarcomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00633789
Phase II Study of Brivanib (BMS-582664) to Treat Multiple Tumor TypesNo drug interventionstreatment2completed
NCT00918489
Study on Efficacy and Tolerability of Vorinostat in Patients With Advanced, Metastatic Soft Tissue Sarcoma (STS)No drug interventionstreatment2completed
NCT02867592
Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare TumorsNo drug interventionstreatment2active_not_recruiting
NCT00186992
Radiation Therapy to Treat Musculoskeletal TumorsNo drug interventionstreatment2active_not_recruiting
NCT00790244
A Scandinavian Sarcoma Group Protocol for Patients With High-risk Soft Tissue Sarcoma of the Extremities and Trunk WallNo drug interventionstreatment2unknown_status
NCT05656144
Cadonilimab in the Treatment of Advanced Soft Tissue SarcomaNo drug interventionstreatment2not_yet_recruiting
NCT01719744
Study of ENMD-2076 in Patients With Advanced/Metastatic Soft Tissue SarcomaNo drug interventionstreatment2completed
NCT00441467
Safety and Efficacy Study of Glufosfamide in Previously Treated Advanced Soft Tissue SarcomaNo drug interventionstreatment2completed
NCT02712567
SARC021C: A Continuation Study of TH-CR-406/SARC021No drug interventionsNot AvailableNot Availableno_longer_available
NCT05776667
Feasibility Trial of Preoperative 5-Day Hypofractionated Radiotherapy for Primary Soft Tissue SarcomaNo drug interventionstreatmentNot Availablerecruiting
NCT05229601
A Study of HFB301001 in Adult Patients With Advanced Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT02527304
Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT00365872
External Beam Radiation With Intratumoral Injection of Dendritic Cells As Neo-Adjuvant Treatment for SarcomaNo drug interventionstreatment2completed
NCT03268772
PLD and IFO As First-line Treatment for Patients With Advanced or Metastatic STSNo drug interventionstreatment2unknown_status
NCT05563272
89Zr-girentuximab for PET Imaging of CAIX Positive Solid TumorsNo drug interventionsdiagnostic2recruiting
NCT03997968
A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid TumorsNo drug interventionstreatment1 / 2active_not_recruiting
NCT05621668
A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone SarcomaNo drug interventionstreatment1recruiting
NCT06436846
Genomic Risk in Retroperitoneal SarcomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03818412
Circulating Tumor DNA in Soft Tissue SarcomaNo drug interventionsotherNot Availablerecruiting
NCT02255110
A Japanese Trial of TH-302 in Subjects With Locally Advanced Unresectable or Metastatic Soft Tissue SarcomaNo drug interventionstreatment2terminated
NCT02634710
Hypofractionated Pre-operative Radiation Therapy for Soft Tissue Sarcomas of the Extremity and Chest-wallNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03618381
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young AdultsNo drug interventionstreatment1recruiting
NCT04091295
BLESSED: Expanded Access for DeltaRex-G for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of BreastNo drug interventionsNot AvailableNot Availableavailable
NCT06413095
PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STSNo drug interventionsbasic_science0completed
NCT03784014
Molecular Profiling of Advanced Soft-tissue SarcomasNo drug interventionshealth_services_research3active_not_recruiting
NCT04577014
Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue SarcomaNo drug interventionstreatment1 / 2active_not_recruiting
NCT06333314
Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSINo drug interventionstreatment2recruiting
NCT05121350
A Clinical Trial to Evaluate the Efficacy and Safety of Anotinib Hydrochloride Capsule Combined With Epirubicin Hydrochloride Versus Placebo Combined With Epirubicin Hydrochloride in First-line Treatment of Advanced Soft Tissue SarcomaNo drug interventionstreatment3unknown_status
NCT01102608
Neoadyuvant High-dose of Ifosfamide and Concurrent Radiotherapy in Soft Tissue SarcomaNo drug interventionstreatment2completed
NCT03449108
LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue SarcomasNo drug interventionstreatment2active_not_recruiting
NCT02199938
Identification and Characterization of Molecular Markers in Musculoskeletal TumorsNo drug interventionsNot AvailableNot Availableterminated
NCT06506838
Anlotinib Combined With Doxorubicin and Radiotherapy as Neoadjuvant Treatment for Soft Tissue SarcomaNo drug interventionstreatment4recruiting
NCT02451943
A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue SarcomaNo drug interventionstreatment3active_not_recruiting
NCT05542433
Phase II Study of Chiauranib Capsule in Advanced or Unresectable Soft Tissue Sarcomatreatment2recruiting
NCT00385203
The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).No drug interventionstreatment2completed
NCT00276302
Safety Study of IPI-504 in Patients With Gastrointestinal Stromal Tumors (GIST) or Soft Tissue Sarcomas (STS)No drug interventionstreatment1completed
NCT00423254
Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.No drug interventionstreatment1completed
NCT02536183
A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumorstreatment1terminated
NCT00687778
11C-Acetate PET/CT Non-FDG-Avid TumorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04425967
Short Course Of Preoperative Radiotherapy in Head and Neck-, Trunk- and Extremity Soft Tissue SarcomasNo drug interventionstreatmentNot Availablerecruiting
NCT04506008
Hypofractionated Radiotherapy Followed by Surgical Resection in the Treatment of Soft Tissue SarcomasNo drug interventionstreatment2recruiting
NCT03946943
Study of Anlotinib Hydrochloride and Toripalimab in Subjects With Unresectable or Metastatic Undifferentiated Pleomorphic SarcomaNo drug interventionstreatment2unknown_status
NCT05739084
Gene Signatures Searching of Sensitivity/Resistance to Neoadjuvant Radiotherapy in Patients With Resectable STSNo drug interventionsNot AvailableNot Availablerecruiting
NCT01830153
RAD001 in Advanced SarcomaNo drug interventionstreatment2completed
NCT04223583
Study on the Treatment of Soft Tissue Sarcoma With First-line Chemotherapy Failure by Anrotenil Hydrochloride CapsuleNo drug interventionstreatment4completed
NCT02636725
Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue SarcomasNo drug interventionstreatment2completed
NCT02575066
Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma PatientsNo drug interventionstreatment2terminated
NCT03149120
Study of Nivolumab With or Without Pazopanib in Metastatic or Unresectable Soft Tissue SarcomasNo drug interventionstreatment2withdrawn
NCT00881595
Proton Chemoradiotherapy for High-Risk Soft Tissue SarcomasNo drug interventionstreatment2withdrawn
NCT01962103
Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid TumorsNo drug interventionstreatment1 / 2completed
NCT03985722
Olaratumab Plus Trabectedin in Advanced Soft-tissue Sarcoma Patients Soft-tissue Sarcoma Patientstreatment1active_not_recruiting
NCT03680430
Evaluation of Adaptive Radiation Therapy in Pre-operative or Exclusive Radiation Therapy for Limb Soft Tissues SarcomasNo drug interventionstreatmentNot Availableunknown_status
NCT02812654
Ifosfamide, Doxorubicin and Hypofractionated Radiotherapy in Neoadjuvant Sarcoma Treatmenttreatment2unknown_status
NCT02897128
Transcutaneous Oxygen as a Predictor of Wound Healing Complications in Preoperatively Radiated Soft Tissue SarcomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02464332
Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing SurgeryNot Available1withdrawn
NCT00860015
Alimta Plus Gemcitabine for Advanced Sarcomatreatment2completed
NCT00753688
Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior TherapyNo drug interventionstreatment3completed
NCT00243685
Chemotherapy Drug Sensitivity Microculture (MiCK) Assay for ApoptosisNo drug interventionstreatment2 / 3completed
NCT00189137
Evaluation of Side Effects and Relative Activity of Two Chemotherapy Regimens in the Treatment Soft Tissue Sarcomatreatment2completed
NCT04216953
MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcomatreatment1 / 2active_not_recruiting
NCT04887298
Study of Liposomal Annamycin for the Treatment of Subjects With Soft-Tissue Sarcomas (STS) With Pulmonary Metastasestreatment1 / 2active_not_recruiting
NCT05515575
A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNAtreatment2active_not_recruiting
NCT04605770
Pemetrexed, Cisplatin With Soft Tissue Sarcomatreatment2unknown_status
NCT04673942
A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid TumorsNo drug interventionstreatment2recruiting
NCT05894018
Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcomatreatment2recruiting
NCT06480396
High Versus Lower Intensity Surveillance Following Resection of Retroperitoneal SarcomaNo drug interventionsdiagnostic3not_yet_recruiting
NCT06128863
Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO Trialtreatment2recruiting
NCT06550765
Safety and Efficacy of Degradable Magnesium Metal Clips in Surgical Margins of Radical Surgery for Malignant Bone and Soft Tissue TumorsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05488366
Immunotherapy Combined With Radiotherapy for Metastatic Sarcomatreatment0recruiting
NCT03815474
Anlotinib Hydrochloride Combined With Epirubicin and Ifosfamide for Soft Tissue Sarcoma Patientstreatment2unknown_status
NCT03798795
Radiomics for Tumor Grading of Soft Tissue Sarcomas.No drug interventionsNot AvailableNot Availablecompleted
NCT03480399
Long Term Morbidity and Quality of Life in Retroperitoneal SarcomasNo drug interventionsNot AvailableNot Availableunknown_status
NCT05138146
A Phase 2 Clinical Study of Evaluation of Recombinant Anti-PD-1 Humanized Monoclonal Antibody Injection (609A) Combined With Doxorubicin Hydrochloride in the Treatment of Metastatic/Unresectable Non-specific Soft Tissue SarcomaNo drug interventionstreatment2not_yet_recruiting
NCT03058406
A Study on Safety and Efficacy in Patients With Soft Tissue SarcomasNo drug interventionsNot AvailableNot Availablecompleted
NCT02793050
Retrospective Study of Trabectedin in Soft Tissue SarcomasNo drug interventionsNot AvailableNot Availablecompleted
NCT02808247
Ph II Nintedanib vs. Ifosfamide in Soft Tissue SarcomaNo drug interventionstreatment2terminated
NCT02929394
Trabectedin Maintenance Post 1st-line in STStreatment3terminated
NCT02309242
Long Term Neurotoxic Effects of Chemotherapy in Survivors of Bone and Soft Tissue Sarcomas. A Retrospective StudyNo drug interventionsscreeningNot Availableunknown_status
NCT02367651
Study of Pazopanib Versus Placebo as Maintenance Therapy for Advanced Soft Tissue SarcomaNo drug interventionstreatment2withdrawn
NCT01995981
Individualizing Pazopanib Therapy by exploRing the Role of Early Metabolic responsE and Drug Exposure as a preDICTor for Treatment Outcome in Patients With STSNo drug interventionsNot AvailableNot Availablecompleted
NCT01185964
A Study of Olaratumab in Soft Tissue SarcomaNo drug interventionstreatment1 / 2completed
NCT00859456
Sunitinib in Certain Subtypes of Soft Tissue SarcomasNo drug interventionstreatment2terminated
NCT00490451
A Study of LY573636-Sodium in the Treatment of Patients With Metastatic Soft Tissue SarcomaNo drug interventionstreatment2completed
NCT00289809
TLC D-99 and Ifosfamide in Metastatic Soft Tissue Sarcoma PatientsNo drug interventionstreatment1 / 2completed
NCT00093080
Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)treatment2completed
NCT00142571
Comparison of Gemcitabine v. Gemcitabine Plus Docetaxel in Unresectable Soft Tissue Sarcomatreatment3completed
NCT00061659
Study Evaluating the Safety and Efficacy of ABT-510 in Subjects With Locally Advanced or Metastatic Soft Tissue Sarcomatreatment2completed
NCT00079950
Efficacy and Safety Evaluation of Pegamotecan (PEG-camptothecin) in Advanced or Metastatic Soft Tissue Sarcomatreatment2suspended
NCT05522257
PSMA Expression and PSMA PET Imaging in Soft Tissue Sarcomas and Urothelial Cell CarcinomasNo drug interventionsdiagnosticNot Availablerecruiting
NCT06263231
A Study to Investigate Efficacy & Safety of INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)treatment3recruiting
NCT01985295
Combined Modality Treatment of Sarcomas of the ExtremitiesNo drug interventionstreatment1completed
NCT05813808
Low-dose Computer Tomography in Follow-up of Soft Tissue SarcomasNo drug interventionsdiagnosticNot Availablecompleted
NCT02994264
A Study to Compare Adjuvant Concurrent Chemoradiation (CCRT) to Adjuvant Radiation Therapy (RT) in Grade 2 and 3 Extremity Soft Tissue SarcomasNo drug interventionsNot AvailableNot Availablecompleted
NCT05296564
Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic CancersNo drug interventionstreatment1 / 2recruiting
NCT04219202
Neoadjuvant Irradiation of Retroperitoneal Soft Tissue Sarcoma With Ions Retro-IonNo drug interventionstreatmentNot Availablerecruiting
NCT04028479
The Registry of Oncology Outcomes Associated With Testing and TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT04172805
Anlotinib Combined With Toripalimab in Refractory and Advanced Soft-tissue SarcomaNo drug interventionstreatment2recruiting
NCT04991883
Analysis of the Molecular Profile of the Mixofibrosarcoma of the ExtremitiesNo drug interventionsNot AvailableNot Availablecompleted
NCT05851456
A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Bone and Soft Tissue TumorsNo drug interventionstreatment0recruiting
NCT05235100
Preoperative IMRT With Concurrent Apatinib for Localised Extremity or Trunk SarcomaNo drug interventionstreatment2recruiting
NCT04248959
Prehabilitation to Improve Cancer Surgery Outcomes in AYA Patients With Extremity SarcomasNo drug interventionssupportive_careNot Availablecompleted
NCT05614375
Endoscopic Surgery in the Treatment of Soft Tissue Sarcoma in Nasal and Paranasal SinusNo drug interventionsNot AvailableNot Availablerecruiting
NCT01949506
(SBRT) and (ART) for Pulmonary Metastases From Soft Tissue SarcomasNo drug interventionstreatmentNot Availablecompleted
NCT03600649
Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related SarcomasNo drug interventionstreatment1active_not_recruiting
NCT06114173
Efficacy and Safety Study of Cardunilizumab in Soft Tissue SarcomaNo drug interventionstreatment0active_not_recruiting
NCT04356872
The Combination of Sintilimab and AI (Doxorubicin, ADM/Ifosfamide, IFO) for the First Line Treatment of Select Type of Metastatic/Unresectable Soft Tissue SarcomaNo drug interventionstreatment2unknown_status
NCT03759704
Metabolic Characteristics of Sarcoma In Vivo Using HP 13-C Magnetic Resonance Spectroscopic Imaging (MRSI)No drug interventionsNot AvailableNot Availablewithdrawn
NCT05193214
A Phase II Study for 609A in the Treatment of Advanced Undifferentiated Pleomorphic SarcomaNo drug interventionstreatment2not_yet_recruiting
NCT05858710
Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue SarcomaNo drug interventionstreatment1recruiting
NCT02415816
Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue SarcomasNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT02326025
A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue SarcomaNo drug interventionsbasic_science1completed
NCT02275286
Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma PatientsNo drug interventionstreatment1 / 2recruiting
NCT01491594
Eltrombopag for the Prevention of Chemotherapy Induced ThrombocytopeniaNo drug interventionsprevention1terminated
NCT00406601
BAY-43-9006 in Advanced, Metastatic Soft Tissue SarcomasNo drug interventionstreatment2completed
NCT00297258
Pazopanib In Patients With Relapsed Or Refractory Soft Tissue SarcomaNo drug interventionstreatment2completed
NCT00204646
Neoadjuvant Adriamycin and Ifosfamide Plus High-Dose ICE in Patients With Soft Tissue Sarcoma (STS)No drug interventionstreatment2completed
NCT00204568
Trofosfamide Versus Adriamycin in Elderly Patients With Soft Tissue Sarcoma (STS)treatment2unknown_status
NCT00204620
Bendamustin Hydrochloride in Patients With Soft Tissue Sarcoma (STS)No drug interventionstreatment2completed
NCT00187174
Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumorstreatment1completed
NCT00130858
a Multicenter Clinical Trial for the Treatment of Children and Adolescents With Soft Tissue Sarcoma Stage 4treatment2completed
NCT00134641
Study of Gemcitabine and Vinorelbine in Soft Tissue Sarcomastreatment2completed
NCT06408441
The Epithelioid Hemangioendothelioma Registry of the European Reference Network on Rare Adult Solid Cancers (EURACAN)No drug interventionsNot AvailableNot Availablerecruiting
NCT04347122
Tranexamic Acid in Radical Resection and Endoprosthetic ReconstructionNo drug interventionstreatment4completed
NCT05167994
Preoperative IMRT With Concurrent Anlotinib for Localised Extremity or Trunk SarcomaNo drug interventionstreatment2unknown_status
NCT04595994
Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma and OsteosarcomaNo drug interventionstreatment1recruiting
NCT03474094
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