NCT06619561
A Phase 2 Study to Evaluate Vimseltinib in Adults with Active Chronic Graft-Versus-Host Disease (cGVHD) treatment 2 not_yet_recruiting NCT05885451
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of AMG 592 in Healthy Japanese Participants basic_science 1 completed NCT05873907
A Study to Evaluate the Safety, Tolerability, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AMG 592 in Healthy Participants basic_science 1 completed NCT06279585
Physical Therapy in Patients Undergoing Allo-HSCT With cGVHD No drug interventions treatment Not Available not_yet_recruiting NCT05919511
Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease No drug interventions Not Available Not Available recruiting NCT05214066
Efficacy and Safety Study of 4-Day ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT prevention 2 unknown_status NCT06244628
Safety and Efficacy of Iguratimod in the Treatment of Chronic GVHD treatment 3 recruiting NCT05604742
Belimumab for Treatment of cGVHD Following Allo-HCT treatment 1 / 2 withdrawn NCT06364319
Efficacy and Safety of Anti-CD25 rhMAb in the Treatment of Steroid-Refractory cGVHD treatment 4 not_yet_recruiting NCT01221766
Impact of Adnexal Involvement of the Severity and Prognosis of Chronic Graft-versus-Host Disease No drug interventions Not Available Not Available completed NCT06458127
Tele-Palliative Care Intervention for Patients With Chronic Graft-Versus-Host Disease No drug interventions supportive_care Not Available not_yet_recruiting NCT06186804
A Phase II Study Evaluating the Efficacy and Safety of ABSK021 (Pimicotinib)) in the Treatment of cGvHD Chronic Graft Versus Host Disease (cGvHD) treatment 2 enrolling_by_invitation NCT05509582
Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias treatment 2 enrolling_by_invitation NCT05502783
Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias treatment 2 recruiting NCT04146207
SHR0302 and Steroid as First Line Therapy for Chronic GVHD treatment 0 recruiting NCT06169722
TDI01 Suspension in the Treatment of Chronic Graft-versus-host Disease (cGVHD)) No drug interventions treatment 1 / 2 recruiting NCT06462365
Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) No drug interventions prevention 1 recruiting NCT06279676
Improvement of Women's Health After Allogeneic Stem Cell Transplantation No drug interventions Not Available Not Available not_yet_recruiting NCT03042676
Electronic Database for the Follow up of the ATG_FamilyStudy No drug interventions Not Available Not Available completed NCT04930562
Efficacy and Safety of BN101 in Subjects With Chronic Graft Versus Host Disease (cGVHD) treatment 2 completed NCT04932564
Leflunomide for Musculoskeletal GVHD After Allogeneic Stem Cell Transplant treatment 2 unknown_status NCT01106833
Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801) treatment 2 / 3 completed NCT04107675
A Safety Study of Liposomal Cyclosporine A to Treat Bronchiolitis After Hematopoietic Transplant (BOSTON-4) treatment 2 terminated NCT04294641
Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease treatment 2 active_not_recruiting NCT02611180
Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease No drug interventions Not Available Not Available recruiting NCT04884204
Systematic Symptom Identification With Disease Specific PROM to Assess Symptoms of Chronic GVHD in Outpatient Care in Patients Post HSCT No drug interventions supportive_care Not Available completed NCT01937468
Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease treatment 1 active_not_recruiting NCT05401955
Physiotherapy and Therapeutic Exercise Program in Graft-versus-host Disease (GvHD) No drug interventions supportive_care Not Available unknown_status NCT00092235
Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease No drug interventions Not Available Not Available recruiting NCT02669251
Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation No drug interventions treatment 1 / 2 recruiting NCT02759731
Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation treatment 1 / 2 completed NCT02322190
Biomarkers in Acute Graft-Versus-Host Disease and Extracorporeal Photopheresis Added to Investigator Chosen Therapies of Steroid Refractory Acute GVHD treatment 2 terminated NCT03683498
Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-host-Disease No drug interventions treatment 1 completed NCT04852692
A Study to Investigate the Comparative Effectiveness of Ibrutinib in Steroid Dependent/Refractory cGVHD Participants No drug interventions Not Available Not Available terminated NCT00495755
Campath in Chronic GVHD treatment 1 completed NCT05544032
Expanded Access Program for Axatilimab in Chronic Graft Versus Host Disease (GVHD) Not Available Not Available available NCT02067832
Predictive Biomarkers For Pediatric Chronic Graft-Versus-Host Disease No drug interventions Not Available Not Available active_not_recruiting NCT05095649
Donor Regulatory T-cells for cGVHD in Patients Who do Not Obtain Complete Remission With Ruxolitinib No drug interventions treatment 2 recruiting NCT06046248
Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease treatment 2 recruiting NCT06143891
A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease. treatment 3 recruiting NCT06388564
A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease treatment 2 recruiting NCT06616415
A Clinical Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Belumosudil in Chinese Adolescents With cGVHD Who Have Had an Inadequate Response to Glucocorticoids or Other Systemic Therapies treatment 4 not_yet_recruiting NCT01804686
A Long-term Extension Study of PCI-32765 (Ibrutinib) treatment 3 enrolling_by_invitation NCT04710576
A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD) treatment 2 active_not_recruiting NCT06263478
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Axatilimab Monotherapy in Japanese Participants With Recurrent or Refractory Active Chronic Graft-Versus-Host Disease treatment 3 recruiting NCT04640025
A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib treatment 2 active_not_recruiting NCT06233110
Ruxolitinib Plus Fostamatinib for Steroid Refractory CGvHD treatment 1 not_yet_recruiting NCT06585774
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease treatment 3 not_yet_recruiting NCT01956903
Treatment of Refractory Acute Graft-Versus-Host Disease by Sequential Infusion of Allogenic Mesenchymal Stem Cell. No drug interventions treatment 1 / 2 completed NCT02749084
Multiple Donor Treg DLI for Severe Refractory Chronic GVHD No drug interventions treatment 1 / 2 completed NCT04431479
Predicting the Quality of Response to Specific Treatments in Patients With cGVHD, PQRST Study No drug interventions Not Available Not Available recruiting NCT03190733
A Optimal Anti-Thymoglobuline (ATG) Dose Decrease cGVHD But Not Increase Leukemia Relapse for Haplo-HSCT prevention 4 unknown_status NCT01898377
Imatinib Mesylate and Mycophenolate Mofetil for Steroid-Refractory Sclerotic/Fibrotic cGVHD in Children treatment 2 terminated NCT04232397
Anlotinib Treatment in Steroid Depenent/Refractory cGVHD treatment 2 terminated NCT04111497
Glasdegib for Chronic Graft-Versus-Host Disease treatment 1 / 2 terminated NCT05993611
Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation treatment 1 recruiting NCT05690971
Psychosocial Mobile App for Chronic Graft-Versus-Host Disease No drug interventions health_services_research Not Available recruiting NCT02491359
Carfilzomib in Treating Patients With Chronic Graft-Versus-Host Disease treatment 2 completed NCT03483675
Discontinuation or Continuation of Immunosuppressive Therapy in Participants With Chronic Graft Versus Host Disease No drug interventions treatment 2 completed NCT04716075
Acalabrutinib in CLL and MCL Patients Subjected to Allogeneic Hematopoietic Stem Cell Transplantation (alloSCT) treatment 2 active_not_recruiting NCT05692713
Polyomic Biomarker Verification in Adult Chronic Graft-Versus-Host Disease (ABLE3.0/CTTC2201) No drug interventions Not Available Not Available recruiting NCT01810718
Phase I/II for Safety and Efficacy of Nilotinib in a Population Steroid-refractory/or Steroid-dependent cGVHD treatment 1 completed NCT02337517
Vismodegib in Treating Patients With Steroid-Refractory Chronic Graft-Versus-Host Disease treatment 2 terminated NCT02701634
Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD) treatment 2 terminated NCT02461134
Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of Ponesimod in Subjects With Symptomatic Chronic GVHD treatment 2 terminated NCT06271616
Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant prevention 2 not_yet_recruiting NCT03584516
GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease treatment 2 / 3 terminated NCT05348096
Efficacy and Safety of Low-dose Ibrutinib and Itraconazole in Chronic Graft Versus Host Disease treatment 2 unknown_status NCT01380535
Extracorporeal Photopheresis (ECP) With Methoxsalen for Chronic Graft Versus Host Disease (cGVHD) treatment 0 completed NCT04202835
ATG Plus PTCy vs ATG for CGVHD Prophylaxis prevention 2 recruiting NCT01964625
Positron Emission Tomography - Computed Tomography (PET-CT) Scanning in Chronic Graft Versus Host Disease (cGvHD) No drug interventions diagnostic Not Available terminated NCT01680965
Ofatumumab as Primary Therapy of Chronic Graft Versus Host Disease treatment 1 / 2 completed NCT01862965
Treatment of Newly Diagnosed Moderate or Severe Chronic Graft-versus-host Disease With Prednisone and Everolimus No drug interventions treatment 2 completed NCT06300320
A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease No drug interventions treatment 2 recruiting NCT02318082
Study of Individual Adult and Pediatric Patient Dose-escalated Interleukin-2 Therapy for Refractory Chronic GVHD treatment 1 completed NCT01903473
Donor Regulatory T Cells Infusion in Patients With Chronic Graft-versus-host Disease (GVHD) prevention 2 terminated NCT05996627
Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease treatment 2 recruiting NCT02340676
A Phase II Trial of Low-Dose Interleukin-2 (IL-2) Added to Extra-Corporeal Photopheresis for Steroid-Refractory cGVHD treatment 2 active_not_recruiting NCT05236062
Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial No drug interventions supportive_care Not Available recruiting NCT02359929
BMT Autologous MSCs for GvHD treatment 1 completed NCT00637689
Improving Outcomes Assessment in Chronic GVHD No drug interventions Not Available Not Available active_not_recruiting NCT05305989
Extended Treatment and Follow-up of Subjects Treated With Belumosudil in Study KD025-208 or Study KD025-213 treatment 2 completed NCT03604692
A Phase 1/2 Study to Evaluate SNDX- 6352 in Participants With Active cGVHD treatment 1 / 2 active_not_recruiting NCT02959944
Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD) treatment 3 completed NCT02966301
Treatment of Chronic Graft Versus Host Disease With Arsenic Trioxide treatment 2 completed NCT03839069
Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis No drug interventions treatment Not Available unknown_status NCT02991846
A Prospective Observational Study for Evaluating CGVHD No drug interventions Not Available Not Available completed NCT01526850
Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Chronic Graft Versus Host Disease treatment 2 / 3 unknown_status NCT02352064
Evaluation of the Diagnostic Value of PET (18F-FDG) in Chronic Graft Versus Host Disease (cGVH) No drug interventions diagnostic Not Available unknown_status NCT01954979
Abatacept to Treat Steroid Refractory Chronic Graft Versus Host Disease (cGVHD) treatment 1 completed NCT04540133
Dexamethasone Solution and Dexamethasone in Mucolox™ treatment 2 completed NCT02513498
Ixazomib Citrate in Treating Patients With Chronic Graft-versus-Host Disease treatment 2 completed NCT01158105
Bortezomib for the Treatment of Refractory Chronic Graft-vs-Host Disease(cGVHD) treatment 2 unknown_status NCT05922761
BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP) treatment 2 recruiting NCT01161628
Rituximab for the Primary Treatment of Denovo Extensive Chronic Graft Versus Host Disease (GVHD) treatment 2 completed NCT02918188
Therapeutic Effects of Hydrogen on Steroid-refractory/or Steroid-dependent cGVHD treatment 2 recruiting NCT04189432
Efficacy and Safety of SCM-CGH in Patients With Steroid-Refractory or Dependent Chronic Graft-Versus-Host Disease No drug interventions treatment 2 active_not_recruiting NCT03790332
Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD) treatment 1 / 2 active_not_recruiting NCT05355675
The Association of Microbiota Composition With cGVHD After Allo-HSCT No drug interventions Not Available Not Available recruiting NCT02291770
Treatment of Chronic Graft-Versus-Host Disease With Mesenchymal Stromal Cells treatment 3 unknown_status NCT05121142
Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease treatment 1 completed NCT05567406
Safety and Efficacy of Oral Belumosudil in Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander Male and Female Participants Aged 12 Years and Above With Chronic Graft Versus Host Disease (cGVHD) After At Least 2 Prior Lines of Systemic Therapy treatment 2 recruiting NCT03557749
Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies No drug interventions Not Available Not Available terminated NCT01028313
A Study of Panobinostat (LBH589) as Second-Line Therapy in Patients With Chronic Graft-Versus-Host Disease treatment 2 withdrawn NCT00815919
Bortezomib Plus Prednisone for Initial Therapy of Chronic Graft Versus Host Disease treatment 2 completed NCT04372524
Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study No drug interventions Not Available Not Available recruiting NCT04212416
Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease treatment 1 active_not_recruiting NCT00656058
Montelukast to Treat Bronchiolitis Obliterans treatment 2 completed NCT01036958
Development and Validation of a Symptom Scale for Children With Chronic Graft-versus-Host Disease No drug interventions Not Available Not Available completed NCT02123966
An Open Label Phase II Trial of Topical Sirolimus for the Treatment of Refractory Oral Chronic Graft-versus-Host-Disease supportive_care 2 terminated NCT04200365
A Study of Itacitinib for the Treatment of Chronic Graft Versus Host Disease (cGVHD) treatment 2 terminated NCT02411474
Tear Cytokine Analysis as a Prediction or Diagnostic Marker in Ocular GvHD No drug interventions Not Available Not Available completed NCT01226420
Alefacept in Subjects With Steroid-Refractory Chronic Graft-versus-Host Disease treatment 2 terminated NCT04446182
Itacitinib (INCB039110) and Extracorporeal Photopheresis (ECP) for First-Line Treatment in Chronic GVHD treatment 2 terminated NCT03422627
Safety and Efficacy of Efavaleukin Alfa in Subjects With Steroid Refractory Chronic Graft Versus Host Disease treatment 1 / 2 terminated NCT04692376
MSC for Treatment of cGVHD After Allo-HSCT treatment 2 unknown_status NCT01765660
Mesenchymal Stem Cells for Treatment of Refractory Chronic Graft-versus-host Disease No drug interventions treatment 2 unknown_status NCT03689894
Ibrutinib Plus Rituximab for cGVHD Following Allo-SCT treatment 1 / 2 terminated NCT01366092
Daily IL-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease treatment 2 active_not_recruiting NCT00271869
Treatment of Chronic GVHD of Liver or Lungs by ECP No drug interventions treatment 2 unknown_status NCT03640481
Efficacy and Safety of KD025 in Subjects With cGVHD After At Least 2 Prior Lines of Systemic Therapy treatment 2 terminated NCT06247150
Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD) No drug interventions other Not Available recruiting NCT01758250
Microvascular and Fibrosis Imaging Study No drug interventions Not Available Not Available completed NCT02040623
Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2) No drug interventions treatment 2 completed NCT03007238
Extracorporeal Photopheresis and Low Dose Aldesleukin in Treating Patients With Steroid Refractory Chronic Graft-Versus-Host Disease treatment 2 completed NCT04944043
A Study of TQ05105 in Patients With Chronic Graft Versus Host Disease No drug interventions treatment 1 / 2 active_not_recruiting