Mucopolysaccharidosis Type VII (DBCOND0063470)

Identifiers

Synonyms
MPS VII / Mucopolysaccharidosis VII / Mucopolysaccharidosis Type 7 / Mucopolysaccharidosis type VII / Other mucopolysaccharidoses / Mucopolysaccharidosis, MPS-VII (disorder) / Deficiency of beta-glucuronidase (disorder) / Sly's syndrome

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Vestronidase alfa
A recombinant beta-glucuronidase used to treat mucopolysaccharidosis VII.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04532047
In Utero Enzyme Replacement Therapy for Lysosomal Storage Diseasestreatment1recruiting
NCT03604835
Mucopolysaccharidosis VII Disease Monitoring ProgramNo drug interventionsNot AvailableNot Availablerecruiting
NCT03775174
Expanded Access to MepseviiNot AvailableNot Availableavailable
NCT02418455
Study of UX003 Recombinant Human Beta-Glucuronidase (rhGUS) Enzyme Replacement Treatment in Mucopolysaccharidosis Type 7, Sly Syndrome (MPS 7) Patients Less Than 5 Years of Agetreatment2completed
NCT02230566
A Phase 3 Study of UX003 Recombinant Human Betaglucuronidase (rhGUS) Enzyme Replacement Therapy in Patients With Mucopolysaccharidosis Type 7 (MPS 7)treatment3completed
NCT02432144
A Study of UX003 Recombinant Human Beta-Glucuronidase (rhGUS) Enzyme Replacement Therapy in Subjects With Mucopolysaccharidosis Type 7, Sly Syndrome (MPS 7)treatment3completed
NCT01870375
Longitudinal Studies of Brain Structure and Function in MPS DisordersNo drug interventionsNot AvailableNot Availablecompleted
NCT05368038
ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening ProgramNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT06036693
MPS (RaDiCo Cohort) (RaDiCo-MPS)No drug interventionsNot AvailableNot Availablerecruiting
NCT05619900
Registry of Patients Diagnosed With Lysosomal Storage DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT05687474
Baby Detect : Genomic Newborn ScreeningNo drug interventionsNot AvailableNot Availablerecruiting
NCT03655223
Early Check: Expanded Screening in NewbornsNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02097251
An Open-Label Treatment Protocol With UX003 rhGUS Enzyme Replacement Therapy for an Advanced Stage MPS 7 PatientNot AvailableNot Availableno_longer_available
NCT01856218
An Open-Label Phase 1/2 Study to Assess the Safety, Efficacy and Dose of Study Drug UX003 Recombinant Human Beta-glucuronidase (rhGUS) Enzyme Replacement Therapy in Patients With Mucopolysaccharidosis Type 7 (MPS 7)treatment1 / 2completed